Phorbol Esters

insulin ; Homo sapiens







57 Article(s)
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Pub. Year
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1 25002582 Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. 2014 Sep 5 1
2 21205932 Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains. 2011 Mar 1
3 21136963 Sensing the insulin signaling pathway with an antibody array. 2009 Dec 1
4 18215133 The binding of PRAS40 to 14-3-3 proteins is not required for activation of mTORC1 signalling by phorbol esters/ERK. 2008 Apr 1 1
5 12614163 Insulin induction of apolipoprotein AI, role of Sp1. 2003 Mar 11 1
6 12376314 Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms. 2002 Nov 2
7 11672436 Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression. 2001 Nov 1 4
8 11915930 Mechanisms of muscle insulin resistance in obese individuals. 2001 Dec 1
9 10830281 Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells. 2000 Jun 1
10 10373474 Multiple promoter elements are required for the stimulatory effect of insulin on human collagenase-1 gene transcription. Selective effects on activator protein-1 expression may explain the quantitative difference in insulin and phorbol ester action. 1999 Jun 25 1
11 9607141 Potentiation of insulin-induced phosphatidylinositol-3 kinase activity by phorbol ester is mediated by protein kinase C epsilon. 1998 Mar 1
12 9877233 Evidence for nitric oxide mediated effects on islet hormone secretory phospholipase C signal transduction mechanisms. 1998 Aug 1
13 9387094 Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase. 1997 Aug 1
14 9402139 Insulin-like growth factor binding protein-1: recent findings and new directions. 1997 Dec 1
15 8561786 Choline phosphate and phorbol ester potentiate the mitogenic effect of insulin by competitive mechanisms in NIH 3T3 fibroblasts. 1996 Jan 17 1
16 8650266 New connections in the regulation of PEPCK gene expression by insulin. 1996 Feb 29 1
17 8663368 Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release. 1996 Jul 26 1
18 8842533 Insulin translocates PKC-epsilon and phorbol esters induce and persistently translocate PKC-beta 2 in BC3H-1 myocytes. 1996 Jun 1
19 8897815 Nitric oxide donor SIN-1 inhibits insulin release. 1996 Oct 1
20 7770008 Effects of G-protein activator fluorides, protein kinase C activator phorbol ester and protein kinase inhibitor on insulin binding and hormonal imprinting of Tetrahymena. 1995 1
21 7797543 Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression. 1995 Jun 30 1
22 7857262 Glycerol-3-phosphate dehydrogenase activity in human lymphocytes: effects of insulin, obesity and weight loss. 1995 Feb 6 1
23 7523864 Identification of cis-elements mediating the stimulation of rat insulin-like growth factor-binding protein-1 promoter activity by dexamethasone, cyclic adenosine 3',5'-monophosphate, and phorbol esters, and inhibition by insulin. 1994 Jun 1
24 7929343 Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor. 1994 Oct 21 1
25 8063733 Insulin and other growth factors induce binding of the ternary complex and a novel protein complex to the c-fos serum response element. 1994 Aug 19 1
26 8382476 Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation. 1993 Feb 15 1
27 8384002 Regulation of System A amino-acid transport activity by phospholipase C and cAMP-inducing agents in skeletal muscle: modulation of insulin action. 1993 Mar 10 1
28 1322137 Control of insulin gene expression by glucose. 1992 Jul 15 1
29 1572414 Regulation of beta-actin gene transcription by insulin and phorbol esters. 1992 Jun 2
30 1650476 Signal transduction convergence: phorbol esters and insulin inhibit phosphoenolpyruvate carboxykinase gene transcription through the same 10-base-pair sequence. 1991 Aug 1 2
31 1946468 Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation. 1991 Nov 15 1
32 2018470 Phorbol ester only partially mimics the effects of insulin on glucose transport and glucose-transporter distribution in 3T3-L1 adipocytes. 1991 Apr 1 2
33 2110001 Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C. 1990 Feb 20 2
34 2163613 Phosphofructokinase 2 and glycolysis in HT29 human colon adenocarcinoma cell line. Regulation by insulin and phorbol esters. 1990 Jun 1 1
35 2173567 TPA inhibits insulin stimulated PIP hydrolysis in fat cell membranes: evidence for modulation of insulin dependent phospholipase C by proteinkinase C. 1990 Oct 30 1
36 2207658 Phorbol esters increase insulin binding in astrocytic glial but not neuronal cells in primary culture from the brain. 1990 Jun 25 4
37 2219271 Short-term effects of cyclosporine on secretagogue-induced insulin release by isolated islets. 1990 Oct 1
38 2547602 The insulin-like effects of phorbol myristate acetate (PMA) in the isolated fat cell. 1989 1
39 2557924 The phosphorylation of p68, a calcium-binding protein associated with the human syncytiotrophoblast submembranous cytoskeleton, is modulated by growth factors, activators of protein kinase C and cyclic AMP. 1989 Dec 14 1
40 2646943 Interactions of TPA and insulin on Na+ transport across frog skin. 1989 Mar 1
41 2690823 Comparison of effects of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets. 1989 Nov 15 1
42 2803236 Further evidence for a two-step model of glucose-transport regulation. Inositol phosphate-oligosaccharides regulate glucose-carrier activity. 1989 Aug 1 2
43 3276673 Identification of c-fos sequences involved in induction by insulin and phorbol esters. 1988 Feb 5 1
44 3280335 Effect of protein kinase C activation and depletion on insulin stimulation of glycogen synthesis in cultured hepatoma cells. 1988 Jan 15 1
45 2820811 Insulin receptor kinase defects as a possible cause of cellular insulin resistance. 1987 Jul 3
46 3300647 Insulin-dependent alterations of phorbol ester binding to adipocyte subcellular constituents. Evidence for the involvement of protein kinase C in insulin action. 1987 Jun 30 2
47 3304983 Phorbol ester inhibition of insulin-stimulated deoxyribonucleic acid synthesis in BC3H-1 myocytes. 1987 Sep 2
48 3526339 Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. 1986 Aug 1
49 3539101 Potentiation of specific association of insulin with HepG2 cells by phorbol esters. 1986 May 15 6
50 2864925 Phorbol ester inhibition of hormonal induction of tyrosine aminotransferase. 1985 Sep 16 1