| 1 |
35014047 | The pro-proliferative effect of insulin in human breast epithelial DMBA-transformed and non-transformed cell lines is PI3K-, mTOR- and GLUT1-dependent. | 2022 Mar |
1 |
| 2 |
35048556 | Engineering a Rapid Insulin Release System Controlled By Oral Drug Administration. | 2022 Mar |
1 |
| 3 |
32755490 | Does high dietary protein intake contribute to the increased risk of developing prediabetes and type 2 diabetes? | 2021 Jan |
1 |
| 4 |
33124663 | Rapamycin Plus Vildagliptin to Recover β-Cell Function in Long-Standing Type 1 Diabetes: A Double-Blind, Randomized Trial. | 2021 Jan 23 |
2 |
| 5 |
33382998 | The crosstalk of hedgehog, PI3K and Wnt pathways in diabetes. | 2021 Feb 15 |
1 |
| 6 |
33482580 | Methionine controls insulin/mammalian target of rapamycin complex 1 activity by modulating tuberous sclerosis complex 2 stability. | 2021 Feb 19 |
1 |
| 7 |
33497611 | G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. | 2021 Feb 4 |
1 |
| 8 |
33522203 | Effect of Shenzhu Tiaopi granule on hepatic insulin resistance in diabetic Goto-Kakizakirats via liver kinase B1/adenosine 5'-monophosphate/mammalian target of rapamycin signaling pathway. | 2021 Feb |
1 |
| 9 |
33977204 | Deletion of Rptor in Preosteoblasts Reveals a Role for the Mammalian Target of Rapamycin Complex 1 (mTORC1) Complex in Dietary-Induced Changes to Bone Mass and Glucose Homeostasis in Female Mice. | 2021 May |
1 |
| 10 |
34122092 | Kun-Dan Decoction Ameliorates Insulin Resistance by Activating AMPK/mTOR-Mediated Autophagy in High-Fat Diet-Fed Rats. | 2021 |
1 |
| 11 |
31794259 | Role of Grb10 in mTORC1-dependent regulation of insulin signaling and action in human skeletal muscle cells. | 2020 Feb 1 |
1 |
| 12 |
31941840 | Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable. | 2020 Jan 16 |
2 |
| 13 |
32655497 | Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues? | 2020 |
1 |
| 14 |
32759469 | Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity. | 2020 Aug 31 |
1 |
| 15 |
32779245 | Acne as an altered dermato-endocrine response problem. | 2020 Sep |
1 |
| 16 |
32865663 | Antioxidant Modulation of mTOR and Sirtuin Pathways in Age-Related Neurodegenerative Diseases. | 2020 Dec |
1 |
| 17 |
32879008 | Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling. | 2020 Sep 22 |
1 |
| 18 |
30647914 | Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates. | 2019 |
1 |
| 19 |
30863363 | Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes. | 2019 |
1 |
| 20 |
31044492 | Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris: A randomized open-labeled study. | 2019 Jul |
1 |
| 21 |
31115485 | Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model. | 2019 Jul |
1 |
| 22 |
31167878 | Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance. | 2019 Sep |
1 |
| 23 |
31406105 | Fasting and rapamycin: diabetes versus benevolent glucose intolerance. | 2019 Aug 13 |
3 |
| 24 |
28954814 | Adiponectin improves insulin sensitivity via activation of autophagic flux. | 2017 Nov |
1 |
| 25 |
29158477 | Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells. | 2017 Nov 20 |
2 |
| 26 |
29282029 | Docosahexaenoic acid reduces sterol regulatory element binding protein-1 and fatty acid synthase expression and inhibits cell proliferation by inhibiting pAkt signaling in a human breast cancer MCF-7 cell line. | 2017 Dec 28 |
1 |
| 27 |
26719046 | ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma. | 2016 Mar |
1 |
| 28 |
26733005 | Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice. | 2016 Mar |
1 |
| 29 |
27506738 | Autophagy protects human podocytes from high glucose-induced injury by preventing insulin resistance. | 2016 Sep |
1 |
| 30 |
27686967 | Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes. | 2016 Dec |
5 |
| 31 |
27826244 | Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives. | 2016 |
1 |
| 32 |
27922820 | Rapamycin treatment benefits glucose metabolism in mouse models of type 2 diabetes. | 2016 Nov 30 |
1 |
| 33 |
24755936 | Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver. | 2015 Apr |
1 |
| 34 |
24835482 | Engineered hair follicle mesenchymal stem cells overexpressing controlled-release insulin reverse hyperglycemia in mice with type L diabetes. | 2015 |
2 |
| 35 |
25643582 | Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure. | 2015 Mar |
1 |
| 36 |
25801056 | Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway. | 2015 |
1 |
| 37 |
25875045 | Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells. | 2015 Jun |
1 |
| 38 |
26449763 | Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo. | 2015 Oct 9 |
3 |
| 39 |
24650522 | Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. | 2014 Jul |
1 |
| 40 |
24810050 | Rapamycin reverses insulin resistance (IR) in high-glucose medium without causing IR in normoglycemic medium. | 2014 May 8 |
1 |
| 41 |
25242764 | Placental, lipid, and glucidic effects of mammalian target of rapamycin inhibitors: impact on fetal growth and metabolic disorders during pregnancy after solid organ transplantation. | 2014 Sep |
1 |
| 42 |
25330241 | Go-6976 reverses hyperglycemia-induced insulin resistance independently of cPKC inhibition in adipocytes. | 2014 |
1 |
| 43 |
23160140 | The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue. | 2013 Jan 30 |
2 |
| 44 |
23261705 | Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway. | 2013 Feb 5 |
2 |
| 45 |
23648089 | Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive. | 2013 Aug |
1 |
| 46 |
23762265 | Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway. | 2013 |
1 |
| 47 |
23863152 | Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2). | 2013 Aug |
1 |
| 48 |
24085506 | Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes. | 2013 Nov |
1 |
| 49 |
26120590 | Nutrient Excess in AMPK Downregulation and Insulin Resistance. | 2013 Jul-Sep |
1 |
| 50 |
22028412 | Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation. | 2012 Jan 15 |
1 |