Tetradecanoylphorbol Acetate

insulin ; Homo sapiens







79 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 21682666 Insulin targets the Na(+)/K(+) ATPase in enterocytes via PI3K, PKC, and MAPKS. 2011 Aug 2
2 20541543 Inhibitory effect on protein kinase Ctheta by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes. 2010 Sep 10 1
3 20826143 Phorbol 12-myristate 13-acetate inhibits the antilipolytic action of insulin, probably via the activity of protein kinase Cε. 2010 Dec 1 6
4 17647275 Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells. 2008 Feb 15 3
5 18713840 Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. 2008 Nov 1
6 17288985 Translational control of apolipoprotein B mRNA via insulin and the protein kinase C signaling cascades: evidence for modulation of RNA-protein interactions at the 5'UTR. 2007 Mar 1 2
7 14556646 Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo. 2004 Jan 15 1
8 15489127 The characteristics of spontaneously forming physically cross-linked hydrogels composed of two water-soluble phospholipid polymers for oral drug delivery carrier I: hydrogel dissolution and insulin release under neutral pH condition. 2004 Nov 1
9 12409308 Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. 2003 Jan 3 2
10 12376314 Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms. 2002 Nov 3
11 12474565 [Evaluation of the effect of obesity on selected haemostatic and fibrinolytic parameters in peri- and postmenopausal women]. 2002 Sep 1
12 11220710 The influence of weight loss on fibrinolytic and metabolic parameters in obese children and adolescents. 2001 Jan 1
13 11356718 Insulin-induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta. 2001 Jun 2
14 11523909 ATP-Sensitive potassium channels modulate glucose transport in cultured human skeletal muscle cells. 2001 Jun 2
15 11057852 Insulin sensitivity and hemostatic factors in clinically healthy 58-year-old men. 2000 Oct 1
16 11126343 Determinants of haemostatic risk factors for coronary heart disease in obese children and adolescents. 2000 Nov 1
17 10331419 Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells. 1999 May 2
18 10331492 Hyperglycemia in vitro attenuates insulin-stimulated chemokinesis in normal human neutrophils. Role of protein kinase C activation. 1999 May 1
19 10426567 Possible involvement of atypical protein kinase C (PKC) in glucose-sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive but phorbol 12-myristate 13-acetate (PMA) and Gö 6976-insensitive pathway. 1999 Feb 2
20 10494772 Gender differences in the relation between fibrinogen, tissue-type plasminogen activator antigen and markers of insulin resistance: effects of smoking. D.E.S.I.R. Study Group. Data from an Epidemiological Study on Insulin Resistance Syndrome. 1999 Sep 4
21 9519739 Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+. 1998 Mar 2
22 9600088 Phosphatidylinositol 3-kinase is required for the regulation of hepatitis B surface antigen production and mitogen-activated protein kinase activation by insulin but not by TPA. 1998 May 8 2
23 9607141 Potentiation of insulin-induced phosphatidylinositol-3 kinase activity by phorbol ester is mediated by protein kinase C epsilon. 1998 Mar 4
24 9618150 Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes. 1998 Jul 1
25 9877233 Evidence for nitric oxide mediated effects on islet hormone secretory phospholipase C signal transduction mechanisms. 1998 Aug 2
26 9020132 Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation. 1997 Feb 14 2
27 8561786 Choline phosphate and phorbol ester potentiate the mitogenic effect of insulin by competitive mechanisms in NIH 3T3 fibroblasts. 1996 Jan 17 2
28 8663368 Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release. 1996 Jul 26 3
29 8825422 Regulation of distinct pools of protein kinase C delta in beta cells. 1996 Jan 1
30 8843732 Regulation of insulin secretion by phospholipase C. 1996 Sep 2
31 7536887 Effects of chromium on basal and insulin-induced tyrosine phosphorylation in H4 hepatoma cells: comparison with phorbol-12-myristate-13-acetate and sodium orthovanadate. 1995 Apr 1
32 7607614 Effect of insulin on hydrogen peroxide production by human polymorphonuclear leukocytes. Studies with monoclonal anti-insulin receptor antibodies, and an agonist and an inhibitor of protein kinase C. 1995 2
33 7770008 Effects of G-protein activator fluorides, protein kinase C activator phorbol ester and protein kinase inhibitor on insulin binding and hormonal imprinting of Tetrahymena. 1995 2
34 7772059 Insulin inhibits the phosphorylation of alpha-Gi-2 in intact hepatocytes. 1995 Jun 1 1
35 7981246 Possible involvement of phosphatidylinositol-specific phospholipase C related to pertussis toxin-sensitive GTP-binding proteins during adipocyte differentiation of 3T3-L1 fibroblasts: negative regulation of protein kinase C. 1994 Nov 10 2
36 7988415 Evidence for diverse roles of protein kinase-C in the inhibition of gene expression by insulin: the tyrosine aminotransferase, albumin, and phosphoenolpyruvate carboxykinase genes. 1994 Dec 2
37 8139548 rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. 1994 Apr 1
38 8175693 Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf. 1994 Apr 29 2
39 8195229 Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation. 1994 Jun 3 2
40 8382476 Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation. 1993 Feb 15 7
41 8393875 Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells. 1993 Aug 5 1
42 1309816 Activation of insulin-epidermal growth factor (EGF) receptor chimerae regulates EGF receptor binding affinity. 1992 Feb 1
43 1322137 Control of insulin gene expression by glucose. 1992 Jul 15 2
44 1379255 Role of protein kinase-C in regulation of insulin-like growth factor-binding protein-1 production by HepG2 cells. 1992 Aug 1
45 1417911 Effects of insulin and a tumour promoter, TPA, on glucose transport and metabolism in retinal pigmented epithelium in vitro. 1992 Aug 2
46 1550850 Glucose transport by cultured human fibroblasts: regulation by phorbol esters and insulin. 1992 Feb 17 2
47 1576354 Fat-induced changes in mouse pancreatic islet insulin secretion, insulin biosynthesis and glucose metabolism. 1992 1
48 1735455 Stimulation of proliferation of HL60 cells by low concentrations of 12-O-tetradecanoylphorbol-13-acetate and its relationship to the mitogenic effects of insulin. 1992 Mar 4
49 1665832 Tumor-promoting phorbol ester acts synergistically with insulin to induce lutropin receptor expression in rat granulosa cells. 1991 Oct 6
50 1703443 Possible involvement of pertussis toxin-sensitive GTP-binding protein(s) in c-fos expression during differentiation of 3T3-L1 fibroblasts to adipocytes. 1991 Jan 17 2