Threonine

insulin ; Homo sapiens







198 Article(s)
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51 19724894 Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance. 2009 Oct 2
52 19875456 The phosphatidylinositol 3-kinase/Akt pathway regulates transforming growth factor-{beta} signaling by destabilizing ski and inducing Smad7. 2009 Dec 18 1
53 18215134 Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes. 2008 May 1 1
54 18443205 siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. 2008 Aug 1
55 18469500 Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes. 2008 May 1
56 18577697 Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 Sep 4
57 18615850 Globular adiponectin stimulates glucose transport in type 2 diabetic muscle. 2008 Oct 1
58 18835939 Effect of endothelium-specific insulin resistance on endothelial function in vivo. 2008 Dec 1
59 18927238 Interplay and effects of temporal changes in the phosphorylation state of serine-302, -307, and -318 of insulin receptor substrate-1 on insulin action in skeletal muscle cells. 2008 Dec 2
60 19011679 Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight. 2008 2
61 17098211 Selective cyclooxygenase-2 inhibitors stimulate glucose transport in L6 myotubes in a protein kinase Cdelta-dependent manner. 2007 Feb 1 1
62 17192297 Single nucleotide polymorphisms of the melanocortin-3 receptor gene are associated with substrate oxidation and first-phase insulin secretion in offspring of type 2 diabetic subjects. 2007 Mar 2
63 17227757 Human biliverdin reductase, a previously unknown activator of protein kinase C betaII. 2007 Mar 16 1
64 17291451 Transgenic insulin released from G cells preferentially signals in the liver. 2007 Mar 30 1
65 17360977 Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. 2007 Jun 3
66 17540697 Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle. 2007 Aug 1 1
67 17556533 Molecular mechanism of bis(maltolato)oxovanadium(IV)-induced insulin signaling in 3T3-L1 and IM9 cells: impact of dexamethasone. 2007 Jun 1
68 17601993 Inhibition of lipolysis stimulates peripheral glucose uptake but has no effect on endogenous glucose production in HIV lipodystrophy. 2007 Aug 1
69 17881328 Pharmacology of insulin detemir. 2007 Aug 1
70 17884811 The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice. 2007 Nov 30 1
71 15990193 Extracellular superoxide dismutase gene polymorphism is associated with insulin resistance and the susceptibility to type 2 diabetes. 2006 Feb 1
72 16527823 Hormonal control of reversible translocation of perilipin B to the plasma membrane in primary human adipocytes. 2006 Apr 28 2
73 16839860 Insulin resistance and cardiovascular risk: New insights from molecular and cellular biology. 2006 Aug 1
74 16908951 Thr-encoding allele homozygosity at codon 54 of FABP 2 gene may be associated with impaired delta 6 desatruase activity and reduced plasma arachidonic acid in obese children. 2006 Aug 1
75 17130651 Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. 2006 Dec 1
76 15671481 Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance. 2005 Jan 25 1
77 15787606 Modulation of insulin signalling by insulin sensitizers. 2005 Apr 2
78 15797963 The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. 2005 Jun 2
79 16099431 Insulin-induced stimulation of JNK and the PI 3-kinase/mTOR pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes. 2005 Sep 30 1
80 16128672 A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration. 2005 Dec 1 1
81 16129678 The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal. 2005 Nov 11 1
82 16215634 Mutational analysis of the absolutely conserved B8Gly: consequence on foldability and activity of insulin. 2005 Oct 2
83 16356119 Proposed mechanisms for the induction of insulin resistance by oxidative stress. 2005 Nov-Dec 1
84 15069082 ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. 2004 Jun 11 1
85 15100098 Phosphatidylinositol 3,4,5-trisphosphate: an early mediator of insulin-stimulated sodium transport in A6 cells. 2004 Aug 1
86 15123681 Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus. 2004 Jul 2 4
87 15294058 The molecular mechanism linking muscle fat accumulation to insulin resistance. 2004 May 3
88 15379552 Identification of major ERK-related phosphorylation sites in Gab1. 2004 Sep 28 2
89 15494022 Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance. 2004 Nov 2
90 15610006 Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. 2004 Dec 28 1
91 12510059 Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation. 2003 Mar 7 1
92 12627878 Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats. 2003 Feb 1
93 12631734 Mutant proinsulin that cannot be converted is secreted efficiently from primary rat beta-cells via the regulated pathway. 2003 Mar 1
94 12763864 Phosphorylation of the Na+,K+-ATPase in skeletal muscle: potential mechanism for changes in pump cell-surface abundance and activity. 2003 Apr 1
95 12941788 Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits. 2003 Sep 1
96 13679012 The A54T polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of GIP that potentiates the adverse impact of fatty diets on insulin sensitivity. 2003 Oct 1
97 13679577 Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation. 2003 Sep 30 1
98 14584587 IRS-1 regulation in health and disease. 2003 Jul 2
99 14641043 Insulin signalling, exercise and cellular integrity. 2003 Dec 1
100 11792863 Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. 2002 Jan 22 1