Threonine

insulin ; Homo sapiens







198 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33581131 Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study. 2021 May 2
2 34034636 Insulin reverses choriocarcinoma 5- fluorouracil resistance. 2021 Dec 2
3 34951366 Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B. 2021 1
4 32964344 Insulin Resistance the Hinge Between Hypertension and Type 2 Diabetes. 2020 Dec 1
5 33133020 Altered Serum Amino Acid and Acylcarnitine Profiles in Hyperinsulinemic Hypoglycemia and Ketotic Hypoglycemia. 2020 1
6 30261343 Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate. 2019 Jan 1
7 31039402 Expression, purification, and characterization of the Degludec precursor DesB30. 2019 Sep 1
8 29484855 Paternal high-fat diet enhances offspring whole-body insulin sensitivity and skeletal muscle insulin signaling early in life. 2018 Mar 2
9 30121911 Modulation of the Inflammatory Status of Macrophages and Their Paracrine Effect on the Sensitivity of Adipocytes to Insulin with Sirtuin and PPARγ Receptor Activators. 2018 Aug 1
10 26621633 Role of selected amino acids on plasma IGF-I concentration in infants. 2017 Mar 1
11 27207509 Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes. 2016 Aug 1
12 27422524 Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function. 2016 Jul 15 1
13 25627174 Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces. 2015 Mar 1
14 26201515 Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response. 2015 Oct 1 1
15 26321373 Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation. 2015 Nov 1 2
16 26604643 Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis. 2015 Nov 21 1
17 24652289 Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. 2014 May 2 5
18 24768767 GARNL1, a major RalGAP α subunit in skeletal muscle, regulates insulin-stimulated RalA activation and GLUT4 trafficking via interaction with 14-3-3 proteins. 2014 Aug 1
19 24876356 Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise. 2014 Aug 1 1
20 24879834 The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle. 2014 Nov 3
21 25224502 Calcium signaling in insulin action on striated muscle. 2014 Nov 1
22 25580119 Alternate Phosphorylation/O-GlcNAc Modification on Human Insulin IRSs: A Road towards Impaired Insulin Signaling in Alzheimer and Diabetes. 2014 4
23 23752133 Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle. 2013 Jun 10 3
24 23801578 Impairments in site-specific AS160 phosphorylation and effects of exercise training. 2013 Oct 2
25 22158866 Inhibition of insulin signaling in endothelial cells by protein kinase C-induced phosphorylation of p85 subunit of phosphatidylinositol 3-kinase (PI3K). 2012 Feb 10 1
26 22291472 Insulin detemir for the treatment of obese patients with type 2 diabetes. 2012 1
27 22728334 Protein phosphatase 1 regulatory subunit 12A and catalytic subunit δ, new members in the phosphatidylinositide 3 kinase insulin-signaling pathway. 2012 Sep 1
28 22869320 Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. 2012 Oct 2
29 22937917 Insulin-stimulated phosphorylation of protein phosphatase 1 regulatory subunit 12B revealed by HPLC-ESI-MS/MS. 2012 Sep 1 1
30 23093664 Plasma exposure to insulin glargine and its metabolites M1 and M2 after subcutaneous injection of therapeutic and supratherapeutic doses of glargine in subjects with type 1 diabetes. 2012 Dec 1
31 21189360 In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes. 2011 Mar 1
32 21296137 Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway. 2011 Jul 14 1
33 21355052 Activation of PI3-kinase stimulates endocytosis of ROMK via Akt1/SGK1-dependent phosphorylation of WNK1. 2011 Mar 1
34 21559284 Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load. 2011 May 3 1
35 21573217 ENPP1 affects insulin action and secretion: evidences from in vitro studies. 2011 May 5 1
36 21708268 Preparation of monomeric B27 Lys destripeptide insulin by intein mediated expression in Escherichia coli. 2011 Nov 1
37 21850561 Global IRS-1 phosphorylation analysis in insulin resistance. 2011 Nov 1
38 19925457 Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis. 2010 Jan 27 1
39 19940100 Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle. 2010 Feb 2
40 19959476 Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family. 2010 Feb 12 3
41 20022950 Dissecting the mechanism of insulin resistance using a novel heterodimerization strategy to activate Akt. 2010 Feb 19 1
42 20051528 Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation. 2010 Apr 1
43 20153289 Stearoyl-CoA desaturase and insulin signaling--what is the molecular switch? 2010 Jun-Jul 3
44 20181984 GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis. 2010 Jul 1
45 20515662 The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling. 2010 Jul 2 1
46 20594869 Label-free relative quantification of co-eluting isobaric phosphopeptides of insulin receptor substrate-1 by HPLC-ESI-MS/MS. 2010 Sep 1
47 20826143 Phorbol 12-myristate 13-acetate inhibits the antilipolytic action of insulin, probably via the activity of protein kinase Cε. 2010 Dec 1 1
48 18728222 Phosphorylation of IRS proteins, insulin action, and insulin resistance. 2009 Apr 1
49 19115062 Insulin enhances proliferation and viability of human umbilical vein endothelial cells. 2009 Feb 2
50 19150387 Angiotensin II and the development of insulin resistance: implications for diabetes. 2009 Apr 29 1