Troglitazone

insulin ; Homo sapiens







200 Article(s)
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1 35059243 The forgotten type 2 diabetes mellitus medicine: rosiglitazone. 2022 Jan 1
2 23024191 Glitazones exert multiple effects on β-cell stimulus-secretion coupling. 2013 Jan 1
3 21081660 A gene expression signature for insulin resistance. 2011 Feb 11 1
4 21779873 Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes Prevention Program. 2011 Oct 2
5 20805226 Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes. 2010 Nov 5 1
6 21105563 Metformin and troglitazone in the treatment of female infertility associated with polycystic ovarian syndrome. 2009 Oct-Dec 1
7 18284435 Adiponectin and its response to thiazolidinediones are associated with insulin-mediated glucose metabolism in type 2 diabetic patients and their first-degree relatives. 2008 Nov 2
8 17716671 Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. 2007 Sep 4 1
9 16246375 Effect of ecdysterone on glucose metabolism in vitro. 2006 Feb 2 2
10 16483873 Effect of troglitazone on tumor necrosis factor alpha and transforming growth factor beta expression and action in human adipocyte precursor cells in primary culture. 2006 Mar 3
11 16677059 Thiazolidinediones for the therapeutic management of polycystic ovary syndrome : impact on metabolic and reproductive abnormalities. 2006 3
12 16801577 Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. 2006 Jul 3
13 15793255 Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. 2005 Apr 2
14 15798962 Improvement of liver function parameters in patients with type 2 diabetes treated with thiazolidinediones. 2005 Apr 1
15 15834551 Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells. 2005 May 1
16 16020878 Insulin resistance contributes to obesity-related proteinuria. 2005 Jun 2
17 16039647 Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase. 2005 Aug 22 1
18 16093575 Anti-inflammatory effects of troglitazone in nondiabetic obese subjects independent of changes in insulin sensitivity. 2005 Jul-Aug 1
19 16115720 Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction. 2005 Dec 1
20 16179348 Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors. 2005 Nov 18 3
21 16232315 Prevalence, predisposition and prevention of type II diabetes. 2005 Oct 18 1
22 16388091 The metabolic effects of troglitazone in patients with diabetes and end-stage renal disease. 2005 Nov 1
23 14693409 Decrease in serum C-reactive protein levels by troglitazone is associated with pretreatment insulin resistance, but independent of its effect on glycemia, in type 2 diabetic subjects. 2004 Jan 3
24 14693981 Effects of troglitazone in young first-degree relatives of patients with type 2 diabetes. 2004 Jan 4
25 15117549 Ethanol impairs insulin's actions through phosphatidylinositol 3-kinase. 2004 Spring 1
26 15161789 Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabetes (TRIPOD) study. 2004 Jun 1
27 15311105 Improvement of insulin resistance by troglitazone ameliorates cardiac sympathetic nervous dysfunction in patients with essential hypertension. 2004 Sep 4
28 15316457 Therapeutic approaches in the prevention of cardiovascular disease in metabolic syndrome and in patients with type 2 diabetes. 2004 Sep 1
29 15733404 [Ovarian insulin resistance and insulin sensitizer effect on polycystic ovary syndrome]. 2004 Dec 3
30 12574183 Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome. 2003 Feb 2
31 12601628 The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial. 2003 Feb 1
32 12639698 Acute effects of troglitazone and nitric oxide on glucose uptake in L929 fibroblast cells. 2003 Apr 11 2
33 12728539 Long-term cardiovascular effects of insulin sensitizer troglitazone on non-diabetic individuals with insulin resistance: double blind, prospective randomized study. 2003 Apr 6
34 12732844 A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. 2003 May 1
35 12749433 Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome. 2003 Apr 4
36 12914525 Insulin-sparing effects of troglitazone in rat pancreatic islets. 2003 Aug 3
37 12917943 Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome. 2003 1
38 14506629 The impact of an insulin sensitizer, troglitazone, on glucose metabolism in African Americans at risk for type 2 diabetes mellitus: a placebo-controlled, 24-month randomized study. 2003 Sep 1
39 14556818 Selective ovary resistance to insulin signaling in women with polycystic ovary syndrome. 2003 Oct 2
40 14570054 [A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus]. 2003 1
41 14602740 Minimal response of circulating lipids in women with polycystic ovary syndrome to improvement in insulin sensitivity with troglitazone. 2003 Nov 5
42 11751282 Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. 2002 Jan 3
43 11756319 Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. 2002 Jan 4
44 11812753 Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects. 2002 Feb 4
45 11833043 Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus. 2002 Feb 2
46 11874944 Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes. 2002 Mar 3
47 11889176 Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro. 2002 Mar 8
48 11947963 Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus. 2002 Jun 4
49 12009391 Troglitazone: a possible modulator of ovarian steroidogenesis. 2002 May-Jun 3
50 12145147 Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes. 2002 Aug 3