| 1 |
34826616 | HuaChanSu suppresses tumor growth and interferes with glucose metabolism in hepatocellular carcinoma cells by restraining Hexokinase-2. | 2022 Jan |
2 |
| 2 |
34973450 | Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease. | 2022 Feb |
2 |
| 3 |
35563663 | Exploiting the Metabolic Consequences of PTEN Loss and Akt/Hexokinase 2 Hyperactivation in Prostate Cancer: A New Role for δ-Tocotrienol. | 2022 May 9 |
1 |
| 4 |
33744226 | Rabeprazole suppresses cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis. | 2021 Jun |
1 |
| 5 |
33753739 | SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis. | 2021 Mar 22 |
1 |
| 6 |
33760124 | HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin. | 2021 May |
1 |
| 7 |
33809182 | A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism. | 2021 Mar 12 |
2 |
| 8 |
34052833 | ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling. | 2021 May 29 |
1 |
| 9 |
34236032 | [Knockdown of hexokinase 2 (HK2) inhibits breast cancer cell proliferation and reduces their resistance to fluorouracil]. | 2021 Aug |
1 |
| 10 |
34737635 | Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma. | 2021 |
1 |
| 11 |
34954904 | Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic glycolysis. | 2021 Dec |
1 |
| 12 |
31628462 | Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain. | 2020 Jul 14 |
4 |
| 13 |
33160373 | Enhanced antitumor effects of follicle-stimulating hormone receptor-mediated hexokinase-2 depletion on ovarian cancer mediated by a shift in glucose metabolism. | 2020 Nov 7 |
1 |
| 14 |
33204264 | Upregulated Long Noncoding RNA UCA1 Enhances Warburg Effect via miR-203/HK2 Axis in Esophagal Cancer. | 2020 |
1 |
| 15 |
30144070 | Caveolin enhances hepatocellular carcinoma cell metabolism, migration, and invasion in vitro via a hexokinase 2-dependent mechanism. | 2019 Feb |
1 |
| 16 |
30462852 | 3-Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor André Goffeau. | 2019 Apr |
1 |
| 17 |
30770778 | Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis. | 2019 Feb 15 |
1 |
| 18 |
30871777 | Fubp1 supports the lactate-Akt-mTOR axis through the upregulation of Hk1 and Hk2. | 2019 Apr 23 |
1 |
| 19 |
30952834 | B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2. | 2019 Apr 5 |
1 |
| 20 |
31212816 | Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades. | 2019 Jun 12 |
2 |
| 21 |
31270843 | Hexokinase2 controls angiogenesis in melanoma by promoting aerobic glycolysis and activating the p38-MAPK signaling. | 2019 Dec |
1 |
| 22 |
31428701 | Compression-induced expression of glycolysis genes in CAFs correlates with EMT and angiogenesis gene expression in breast cancer. | 2019 |
1 |
| 23 |
31524259 | miR‑185 regulates the growth of osteosarcoma cells via targeting Hexokinase 2. | 2019 Sep |
1 |
| 24 |
29386513 | Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin. | 2018 Jan 31 |
1 |
| 25 |
29440331 | Dysregulated Pseudogene HK2P1 May Contribute to Preeclampsia as a Competing Endogenous RNA for Hexokinase 2 by Impairing Decidualization. | 2018 Apr |
1 |
| 26 |
29763606 | MiR-216a-5p/Hexokinase 2 axis regulates uveal melanoma growth through modulation of Warburg effect. | 2018 Jul 2 |
1 |
| 27 |
29777095 | Butein Inhibited In Vitro Hexokinase-2-Mediated Tumor Glycolysis in Hepatocellular Carcinoma by Blocking Epidermal Growth Factor Receptor (EGFR). | 2018 May 19 |
1 |
| 28 |
29864622 | Proteomics analysis demonstrating rosmarinic acid suppresses cell growth by blocking the glycolytic pathway in human HepG2 cells. | 2018 Sep |
1 |
| 29 |
30013360 | By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma. | 2018 |
1 |
| 30 |
30054337 | Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma. | 2018 Sep 15 |
1 |
| 31 |
30631356 | Glucose and Lactate Transport in Pancreatic Cancer: Glycolytic Metabolism Revisited. | 2018 |
1 |
| 32 |
27363977 | Hexokinase 2 in colorectal cancer: a potent prognostic factor associated with glycolysis, proliferation and migration. | 2017 Apr |
1 |
| 33 |
28025745 | MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells. | 2017 Mar |
1 |
| 34 |
28445971 | STAT3 regulates glycolysis via targeting hexokinase 2 in hepatocellular carcinoma cells. | 2017 Apr 11 |
1 |
| 35 |
28704425 | In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. | 2017 |
1 |
| 36 |
28915575 | Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer. | 2017 Aug 22 |
4 |
| 37 |
26607110 | miR-4458 suppresses glycolysis and lactate production by directly targeting hexokinase2 in colon cancer cells. | 2016 Jan 1 |
5 |
| 38 |
26831667 | Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway. | 2016 Aug |
1 |
| 39 |
25761777 | PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation. | 2015 Mar 12 |
1 |
| 40 |
26054020 | MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer. | 2015 Oct |
2 |
| 41 |
26116768 | PI3K/Akt signaling mediated Hexokinase-2 expression inhibits cell apoptosis and promotes tumor growth in pediatric osteosarcoma. | 2015 Aug 21 |
1 |
| 42 |
26607087 | [miR-181c inhibits glycolysis by targeting hexokinase 2 in cancer-associated fibroblasts]. | 2015 Nov |
3 |
| 43 |
22382780 | 3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue. | 2012 Feb |
1 |
| 44 |
19690031 | Evaluation of the role of hexokinase type II in cellular proliferation and apoptosis using human hepatocellular carcinoma cell lines. | 2009 Sep |
1 |