| 1 |
34990518 | Dendritic Polyglycerol-Conjugated Gold Nanostars for Metabolism Inhibition and Targeted Photothermal Therapy in Breast Cancer Stem Cells. | 2022 Apr |
1 |
| 2 |
35355227 | Role of endoplasmic reticulum stress in apoptosis induced by HK2 inhibitor and its potential as a new drug combination strategy. | 2022 May |
2 |
| 3 |
35427437 | Novel Hydrazone Derivatives of 3-Bromopyruvate: Synthesis, Evaluation of the Cytotoxic Effects, Molecular Docking and ADME Studies. | 2022 Jun |
4 |
| 4 |
34378321 | Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer. | 2021 Sep |
2 |
| 5 |
34763086 | lncRNA Linc00173 modulates glucosemetabolism and multidrug chemoresistancein SCLC: Potential molecular panel for targeted therapy. | 2021 Nov 8 |
1 |
| 6 |
32165307 | TRIM59 knockdown blocks cisplatin resistance in A549/DDP cells through regulating PTEN/AKT/HK2. | 2020 Jul 15 |
1 |
| 7 |
32330495 | 3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells. | 2020 Jul |
2 |
| 8 |
33149623 | Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy. | 2020 |
2 |
| 9 |
30875800 | Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma. | 2019 Mar 14 |
4 |
| 10 |
31506393 | Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin. | 2019 Sep 30 |
5 |
| 11 |
28980855 | Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2). | 2018 |
1 |
| 12 |
29320411 | Inihibition of Glycolysis by Using a Micro/Nano-Lipid Bromopyruvic Chitosan Carrier as a Promising Tool to Improve Treatment of Hepatocellular Carcinoma. | 2018 Jan 10 |
1 |
| 13 |
28433696 | FOXC2 positively regulates YAP signaling and promotes the glycolysis of nasopharyngeal carcinoma. | 2017 Aug 1 |
1 |
| 14 |
26740252 | The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. | 2016 Jan 6 |
1 |
| 15 |
26893781 | Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. | 2016 Feb |
4 |
| 16 |
26986252 | Hexokinase 2 is a determinant of neuroblastoma metastasis. | 2016 Mar 29 |
2 |
| 17 |
27983708 | The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate. | 2016 Dec 15 |
1 |
| 18 |
25229889 | Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro. | 2015 Jan |
1 |
| 19 |
25709804 | The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate. | 2015 Mar |
2 |
| 20 |
26185443 | Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis. | 2015 |
2 |
| 21 |
24738957 | 3-Bromopyruvic acid, a hexokinase II inhibitor, is an effective antitumor agent on the hepatoma cells : in vitro and in vivo findings. | 2014 Jun |
3 |
| 22 |
25053988 | Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cells. | 2014 Mar |
3 |
| 23 |
25372840 | The reversal effects of 3-bromopyruvate on multidrug resistance in vitro and in vivo derived from human breast MCF-7/ADR cells. | 2014 |
1 |
| 24 |
24071366 | Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect). | 2013 Nov |
1 |
| 25 |
22298254 | Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate. | 2012 Feb |
2 |
| 26 |
22322891 | Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase. | 2012 Feb |
1 |
| 27 |
22350012 | Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition. | 2012 Feb |
2 |
| 28 |
19101634 | Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy. | 2009 Feb |
2 |
| 29 |
19285479 | Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. | 2009 May |
3 |
| 30 |
19067133 | Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells : ROS-mediated cell death by 3-BrPA. | 2008 Dec |
4 |
| 31 |
17672972 | [Expression of hexokinase-II gene in human colon cancer cells and the therapeutic significance of inhibition thereof]. | 2007 Apr 17 |
2 |