Afatinib

neuregulin 1 ; Homo sapiens







9 Article(s)
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1 35135829 Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements. 2022 May 2 1
2 35400204 Plain language summary of publication: new information for the potential role of afatinib in treating people with NRG1 gene fusion-positive cancer. 2022 Jun 5
3 32852072 Therapeutic Potential of Afatinib in NRG1 Fusion-Driven Solid Tumors: A Case Series. 2021 Jan 7
4 34805369 Successful targeting of the NRG1 fusion reveals durable response to afatinib in lung adenocarcinoma: a case report. 2021 Oct 1
5 32916265 NRG1 fusion-driven tumors: biology, detection, and the therapeutic role of afatinib and other ErbB-targeting agents. 2020 Dec 2
6 31068372 NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma. 2019 Aug 1 4
7 30568455 Afatinib reverses ceritinib resistance (CR) in ALK/ROS1-positive non-small-cell lung cancer cell (NSCLC) via suppression of NRG1 pathway. 2018 5
8 28502724 Durable Response to Afatinib in Lung Adenocarcinoma Harboring NRG1 Gene Fusions. 2017 Aug 1
9 29169524 A Case of Invasive Mucinous Pulmonary Adenocarcinoma with a CD74-NRG1 Fusion Protein Targeted with Afatinib. 2017 Dec 1