| 1 |
35429653 | Novel biallelic mutations in the DUOX2 gene underlying very early-onset inflammatory bowel disease: A case report. | 2022 May |
4 |
| 2 |
32767144 | Oxidants in Physiological Processes. | 2021 |
1 |
| 3 |
34019632 | Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism. | 2021 Aug 1 |
2 |
| 4 |
34197086 | Conjugated Polymer-Ferrocence Nanoparticle as an NIR-II Light Powered Nanoamplifier to Enhance Chemodynamic Therapy. | 2021 Jul 14 |
1 |
| 5 |
31678720 | Proton channel blockers inhibit Duox activity independent of Hv1 effects. | 2020 Jan |
1 |
| 6 |
30318012 | NADPH Oxidase as a Target for Modulation of Radiation Response; Implications to Carcinogenesis and Radiotherapy. | 2019 |
1 |
| 7 |
31083324 | H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases. | 2019 May 10 |
3 |
| 8 |
31172466 | Purification and Characterization of DUOX Peroxidase Homology Domains (PHDs). | 2019 |
2 |
| 9 |
31172499 | DUOX Defects and Their Roles in Congenital Hypothyroidism. | 2019 |
1 |
| 10 |
31513783 | The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model. | 2019 Nov 1 |
4 |
| 11 |
31548328 | IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells. | 2019 Nov 1 |
3 |
| 12 |
29373314 | CRISPR/Cas9-mediated modification of the extreme C-terminus impairs PDGF-stimulated activity of Duox2. | 2018 Apr 25 |
3 |
| 13 |
29435108 | Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter. | 2018 Jan 12 |
5 |
| 14 |
29845893 | Conformation of the N-Terminal Ectodomain Elicits Different Effects on DUOX Function: A Potential Impact on Congenital Hypothyroidism Caused by a H2O2 Production Defect. | 2018 Aug |
3 |
| 15 |
28633507 | Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism. | 2017 Sep 1 |
2 |
| 16 |
28648510 | Disorders of H2O2 generation. | 2017 Mar |
2 |
| 17 |
29272487 | Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans. | 2017 Dec 19 |
1 |
| 18 |
26823467 | Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H2O2 Production. | 2016 Mar 18 |
3 |
| 19 |
27174022 | NADPH oxidases: new actors in thyroid cancer? | 2016 Aug |
1 |
| 20 |
27373512 | Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families. | 2016 Oct |
1 |
| 21 |
27637085 | Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A. | 2016 Oct 18 |
5 |
| 22 |
27864363 | Induction of Airway Allergic Inflammation by Hypothiocyanite via Epithelial Cells. | 2016 Dec 30 |
2 |
| 23 |
25761904 | When an Intramolecular Disulfide Bridge Governs the Interaction of DUOX2 with Its Partner DUOXA2. | 2015 Sep 20 |
1 |
| 24 |
25960956 | DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ. | 2015 Mar |
2 |
| 25 |
26207686 | Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells. | 2015 Aug |
2 |
| 26 |
26261005 | Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine. | 2015 Dec |
2 |
| 27 |
23962049 | Histamine stimulates hydrogen peroxide production by bronchial epithelial cells via histamine H1 receptor and dual oxidase. | 2014 Jan |
1 |
| 28 |
24053146 | Increased concentration of iodide in airway secretions is associated with reduced respiratory syncytial virus disease severity. | 2014 Feb |
2 |
| 29 |
24492313 | DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid. | 2014 Mar |
1 |
| 30 |
24518246 | An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. | 2014 Sep |
2 |
| 31 |
25248169 | High frequency of DUOX2 mutations in transient or permanent congenital hypothyroidism with eutopic thyroid glands. | 2014 |
2 |
| 32 |
23281318 | Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis. | 2013 May |
1 |
| 33 |
23404134 | Genetic defects of hydrogen peroxide generation in the thyroid gland. | 2013 Apr |
2 |
| 34 |
23404210 | Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. | 2013 Apr |
2 |
| 35 |
23545780 | IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response. | 2013 May |
1 |
| 36 |
22301785 | Mice deficient in dual oxidase maturation factors are severely hypothyroid. | 2012 Mar |
2 |
| 37 |
21321110 | Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines. | 2011 Apr 8 |
2 |
| 38 |
21367925 | A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletion. | 2011 May |
1 |
| 39 |
20122987 | Defects of thyroidal hydrogen peroxide generation in congenital hypothyroidism. | 2010 Jun 30 |
2 |
| 40 |
20187165 | Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2-generating enzyme DUOX2 associated with transient congenital hypothyroidism. | 2010 Apr |
1 |
| 41 |
20407074 | Dual oxidase, hydrogen peroxide and thyroid diseases. | 2010 Apr |
3 |
| 42 |
20511343 | All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium. | 2010 Aug |
1 |
| 43 |
19074510 | Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. | 2009 Apr |
2 |
| 44 |
19358684 | Mechanisms and function of DUOX in epithelia of the lung. | 2009 Oct |
1 |
| 45 |
18177232 | Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease. | 2008 Apr |
1 |
| 46 |
18511861 | Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. | 2008 |
1 |
| 47 |
17374849 | Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor. | 2007 Jun |
3 |
| 48 |
16987008 | Regulation of novel superoxide-producing NAD(P)H oxidases. | 2006 Sep-Oct |
1 |
| 49 |
16987011 | Physiology and pathophysiology of the DUOXes. | 2006 Sep-Oct |
1 |
| 50 |
15591162 | Dual oxidase2 is expressed all along the digestive tract. | 2005 May |
3 |