Vitamin D

cytochrome P450, family 27, subfamily b, polypeptide 1 ; Mus musculus







48 Article(s)
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1 33535006 Effects of 1,25 and 24,25 Vitamin D on Corneal Fibroblast VDR and Vitamin D Metabolizing and Catabolizing Enzymes. 2021 Sep 1
2 31629064 Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression. 2020 Feb 1
3 31945466 25(OH)D3 stimulates the expression of vitamin D target genes in renal tubular cells when Cyp27b1 is abrogated. 2020 May 1
4 31702812 BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice. 2019 Dec 1
5 29371756 The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice. 2018 Jan 1
6 29488238 Potencies of vitamin D analogs, 1α-hydroxyvitamin D3 , 1α-hydroxyvitamin D2 and 25-hydroxyvitamin D3 , in lowering cholesterol in hypercholesterolemic mice in vivo. 2018 Apr 1
7 29653103 Sterol regulatory element binding protein 1 trans-activates 25-hydroxy vitamin D3 24-hydroxylase gene expression in renal proximal tubular cells. 2018 Jun 2 1
8 29710028 Vitamin D Deficiency Increases Lipogenesis and Reduces Beta-Oxidation in the Liver of Diet-Induced Obese Mice. 2018 1
9 29771914 Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)2D3. 2018 1
10 30281599 Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice. 2018 1
11 27535551 Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D. 2017 Feb 2
12 28025137 Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice. 2017 Jan 29 2
13 28107527 Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase. 2017 1
14 28808057 A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation. 2017 Oct 20 1
15 28922720 1,25(OH)2D3 deficiency increases TM40D tumor growth in bone and accelerates tumor-induced bone destruction in a breast cancer bone metastasis model. 2017 Nov 1
16 28938443 Microbiota-Dependent Induction of Colonic Cyp27b1 Is Associated With Colonic Inflammation: Implications of Locally Produced 1,25-Dihydroxyvitamin D3 in Inflammatory Regulation in the Colon. 2017 Nov 1 1
17 26704532 Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain. 2016 Apr 1
18 27119753 Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation. 2016 Jun 2
19 25237033 Inferences from genetically modified mouse models on the skeletal actions of vitamin D. 2015 Apr 1
20 26176830 Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype. 2015 Nov 2
21 24247221 Vitamin D and energy homeostasis: of mice and men. 2014 Feb 1
22 24314866 Murine CD8+ T cells but not macrophages express the vitamin D 1α-hydroxylase. 2014 Jan 1
23 24949660 The vitamin D receptor (VDR) is expressed in skeletal muscle of male mice and modulates 25-hydroxyvitamin D (25OHD) uptake in myofibers. 2014 Sep 1
24 22981997 The pleiotropic effects of vitamin D in bone. 2013 Jul 1
25 23858619 Vitamin D action: lessons from VDR and Cyp27b1 null mice. 2013 Jun 1
26 24019880 FGF-23 regulates CYP27B1 transcription in the kidney and in extra-renal tissues. 2013 1
27 22435627 Effects of bisphenol A administration to pregnant mice on serum Ca and intestinal Ca absorption. 2012 Mar 1
28 22454149 Dietary vitamin D₃ and 1,25-dihydroxyvitamin D₃ (calcitriol) exhibit equivalent anticancer activity in mouse xenograft models of breast and prostate cancer. 2012 Jun 1
29 22572998 Peripubertal vitamin D(3) deficiency delays puberty and disrupts the estrous cycle in adult female mice. 2012 Aug 1
30 22648952 VDR and CYP27B1 are expressed in C2C12 cells and regenerating skeletal muscle: potential role in suppression of myoblast proliferation. 2012 Aug 15 2
31 20965147 1,25-Dihydroxyvitamin D is not responsible for toxicity caused by vitamin D or 25-hydroxyvitamin D. 2011 Jan 15 1
32 21307571 The vitamin D3 1alpha-hydroxylase gene and its regulation by active vitamin D3. 2011 1
33 21482732 Vitamin D and the regulation of placental inflammation. 2011 May 15 2
34 19920212 Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney. 2010 Feb 4 1
35 20554701 Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activity. 2010 Sep 1
36 19320717 Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. 2009 Apr 1
37 19829383 DNA demethylation in hormone-induced transcriptional derepression. 2009 Oct 15 3
38 18029472 High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice. 2007 Dec 2
39 16371465 CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1alpha-hydroxylase promoter activity in the skin. 2006 Jan 3 2
40 15972816 Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1. 2005 Aug 26 1
41 16177194 Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice. 2005 Oct 3
42 15225761 Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model. 2004 May 1
43 15225794 Rescue of the phenotype of CYP27B1 (1alpha-hydroxylase)-deficient mice. 2004 May 3
44 12674324 Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: biochemical, histomorphometric, and biomechanical analyses. 2003 Apr 3
45 12689675 Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1). 2003 Apr 3
46 12421875 Phytoestrogens regulate vitamin D metabolism in the mouse colon: relevance for colon tumor prevention and therapy. 2002 Nov 1
47 11416220 Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. 2001 Jun 19 2
48 9295274 25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis. 1997 Sep 19 2