regorafenib

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







8 Article(s)
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1 33922992 Induction of Apoptosis, Inhibition of MCL-1, and VEGF-A Expression Are Associated with the Anti-Cancer Efficacy of Magnolol Combined with Regorafenib in Hepatocellular Carcinoma. 2021 Apr 25 2
2 32024199 Regorafenib Alteration of the BCL-xL/MCL-1 Ratio Provides a Therapeutic Opportunity for BH3-Mimetics in Hepatocellular Carcinoma Models. 2020 Feb 1 3
3 32724460 Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer. 2020 8
4 31238539 Protein Kinase B and Extracellular Signal-Regulated Kinase Inactivation is Associated with Regorafenib-Induced Inhibition of Osteosarcoma Progression In Vitro and In Vivo. 2019 Jun 24 2
5 31349793 Inhibition of cyclin E1 sensitizes hepatocellular carcinoma cells to regorafenib by mcl-1 suppression. 2019 Jul 26 1
6 29682179 Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma. 2018 Mar 30 1
7 27399335 FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation. 2017 Feb 9 2
8 26561209 Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy. 2015 1