Olanzapine

UDP glucuronosyltransferase family 1 member A4 ; Homo sapiens







9 Article(s)
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1 32070304 The association of genetic polymorphisms in CYP1A2, UGT1A4, and ABCB1 with autonomic nervous system dysfunction in schizophrenia patients treated with olanzapine. 2020 Feb 18 3
2 30888624 A Phase I Open-Label Study to Evaluate the Effects of Rifampin on the Pharmacokinetics of Olanzapine and Samidorphan Administered in Combination in Healthy Human Subjects. 2019 May 1
3 23930678 Pharmacogenetics of olanzapine metabolism. 2013 Aug 2
4 22388157 Interindividual variation in olanzapine concentration influenced by UGT1A4 L48V polymorphism in serum and upstream FMO polymorphisms in cerebrospinal fluid. 2012 Apr 1
5 22713701 UGT1A4*3 encodes significantly increased glucuronidation of olanzapine in patients on maintenance treatment and in recombinant systems. 2012 Aug 5
6 21750471 Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants. 2011 Sep 1
7 20143052 Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients. 2010 May 4
8 17038872 Effect of adjunctive lamotrigine treatment on the plasma concentrations of clozapine, risperidone and olanzapine in patients with schizophrenia or bipolar disorder. 2006 Oct 2
9 12404680 Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes. 2002 Jul 2