Nitrogen

UDP glucuronosyltransferase family 1 member A4 ; Homo sapiens







22 Article(s)
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1 35636643 Firm evidence for the detoxification of senecionine-induced hepatotoxicity via N-glucuronidation in UGT1A4-humanized transgenic mice. 2022 Jul 1
2 29572863 Enantioselective capillary electrophoresis provides insight into the phase II metabolism of ketamine and its metabolites in vivo and in vitro. 2018 Jun 1
3 28803208 N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification. 2017 Oct 25 5
4 23371966 Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics. 2013 Apr 2
5 21434773 N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases. 2011 Aug 2
6 20056725 Identification of the UDP-glucuronosyltransferase isozyme involved in senecionine glucuronidation in human liver microsomes. 2010 Apr 5
7 20713656 Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7. 2010 Nov 1
8 19372226 In vitro metabolism of the novel, highly selective oral angiogenesis inhibitor motesanib diphosphate in preclinical species and in humans. 2009 Jul 2
9 17998299 Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes. 2008 Feb 1
10 18256203 Contribution of the N-glucuronidation pathway to the overall in vitro metabolic clearance of midazolam in humans. 2008 May 1
11 17576790 Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. 2007 Sep 1
12 16480962 Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4. 2006 Apr 28 1
13 16713428 N-Glucuronidation of the antiepileptic drug retigabine: results from studies with human volunteers, heterologously expressed human UGTs, human liver, kidney, and liver microsomal membranes of Crigler-Najjar type II. 2006 Jun 1
14 15470160 Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes. 2005 Jan 1
15 15475412 Characterization of afloqualone N-glucuronidation: species differences and identification of human UDP-glucuronosyltransferase isoform(s). 2005 Jan 5
16 14709623 Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4. 2004 Jan 1
17 15135306 Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. 2004 Jun 1 3
18 12167564 N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases. 2002 Sep 1
19 12433823 Characterization of nicotine and cotinine N-glucuronidations in human liver microsomes. 2002 Dec 1
20 10901693 Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes. 2000 Aug 5
21 10506112 Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides. 1999 Oct 1
22 8820428 Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein. 1996 Mar 1