7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







21 Article(s)
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1 28405246 Modulation of benzo[a]pyrene-DNA adduct formation by CYP1 inducer and inhibitor. 2017 1
2 27162022 Resveratrol ameliorates benzo(a)pyrene-induced testicular dysfunction and apoptosis: involvement of p38 MAPK/ATF2/iNOS signaling. 2016 Aug 3
3 23036853 Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells. 2013 Jan 20 2
4 22876118 CYP1A1 protein activity is associated with allelic variation in pterygium tissues and cells. 2012 1
5 20399842 The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation. 2010 Sep 15 2
6 20596254 CYP1A1 gene polymorphisms as a risk factor for pterygium. 2010 Jun 9 1
7 20700368 An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium. 2010 Apr 8 4
8 16557497 Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry. 2006 1
9 15808407 Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene. 2005 Apr 28 1
10 15298956 Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH. 2004 Aug 3
11 12507920 CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. 2002 Dec 5
12 23889309 Benzo(a)pyrene diolepoxide adducts to albumin in workers exposed to polycyclic aromatic hydrocarbons: association with specific CYP1A1, GSTM1, GSTP1 and EHPX genotypes. 2001 1
13 10607731 Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism. 2000 Jan 4
14 10571654 Genetic cancer susceptibility and DNA adducts: studies in smokers, tobacco chewers, and coke oven workers. 1999 1
15 9679569 Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection. 1998 Apr 24 1
16 9718223 Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide. 1998 Aug 1
17 10022748 High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes. 1998 Apr 1
18 10026994 Impact of adduct determination on the assessment of cancer susceptibility. 1998 1
19 8692183 DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationship. 1996 Jun 2
20 7581497 Cytochrome P450 mediated reactions studied in genetically engineered V79 Chinese hamster cells. 1995 1
21 7662121 Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts. 1995 Feb 2