Omeprazole

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







27 Article(s)
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1 35062050 CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver. 2022 Feb 1
2 33355212 Evaluation of Tissue Stem Cell-Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut. 2021 Mar 1
3 25929522 The effects of drugs with immunosuppressive or immunomodulatory activities on xenobiotics-metabolizing enzymes expression in primary human hepatocytes. 2015 Aug 1
4 26187180 Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells. 2015 Sep 1 1
5 26441083 Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2-related factor 2. 2015 Nov 13 2
6 24382322 Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole. 2014 Feb 1
7 24887303 Differential effects of omeprazole and lansoprazole enantiomers on aryl hydrocarbon receptor in human hepatocytes and cell lines. 2014 1
8 22673034 Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers. 2012 1
9 21666223 Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures. 2011 Sep 1
10 18502397 Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements. 2008 Jul 1 7
11 18793272 Omeprazole alleviates benzo[a]pyrene cytotoxicity by inhibition of CYP1A1 activity in human and mouse hepatoma cells. 2008 Nov 7
12 15681896 Effects of NO-1886 (Ibrolipim), a lipoprotein lipase-promoting agent, on gene induction of cytochrome P450s, carboxylesterases, and sulfotransferases in primary cultures of human hepatocytes. 2004 Dec 1
13 12623754 Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+ -ATPase inhibitors and other xenobiotics. 2003 Feb 1
14 11754570 Black tea polyphenols, theaflavins, prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P450 1A1 in cell cultures. 2002 Jan 2 2
15 11849738 Induction of CYP1A1 and CYP1A2 expressions by prototypic and atypical inducers in the human lung. 2002 Apr 8 1
16 12040753 Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR. 2002 May 2
17 12438738 Presence on human chromosome 10 of omeprazole-sensitivity gene whose product mediates CYP1A1 induction. 2002 2
18 10859152 Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. 2000 Jul 1
19 10100022 Species differences in hepatocyte induction of CYP1A1 and CYP1A2 by omeprazole. 1999 Feb 4
20 10445394 Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells. 1999 Jul 4
21 9784250 Induction of cytochrome P-450 1A1 by omeprazole in human HepG2 cells is protein tyrosine kinase-dependent and is not inhibited by alpha-naphthoflavone. 1998 Oct 15 4
22 9041675 Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line. 1997 Jan 1
23 8647108 Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism. 1996 May 1 1
24 7840678 Different inducibility of cytochrome P-4501A1 mRNA of human and mouse by omeprazole in culture cells. 1995 Jan 10 1
25 8386305 Nuclear uptake of the Ah (dioxin) receptor in response to omeprazole: transcriptional activation of the human CYP1A1 gene. 1993 Apr 9
26 1280125 Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor. 1992 Oct 30 1
27 1426869 Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. 1992 Nov 2