ethoxyresorufin

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







61 Article(s)
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1 33394027 Heteromeric complex formation between human cytochrome P450 CYP1A1 and heme oxygenase-1. 2021 Jan 29 2
2 34056284 Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling. 2021 May 4 2
3 34235626 Novel Synthetic Analogues of 19(S/R)-Hydroxyeicosatetraenoic Acid Exhibit Noncompetitive Inhibitory Effect on the Activity of Cytochrome P450 1A1 and 1B1. 2021 Sep 1
4 32741942 Incorporation of Gelatin Microspheres into HepG2 Human Hepatocyte Spheroids for Functional Improvement through Improved Oxygen Supply to Spheroid Core. 2020 1
5 31147316 Nitidine Chloride-Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism. 2019 Aug 1
6 28250275 Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size. 2017 1
7 27265259 Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1. 2016 Jul 15 1
8 27428168 Impaired dacarbazine activation and 7-ethoxyresorufin deethylation in vitro by polymorphic variants of CYP1A1 and CYP1A2: implications for cancer therapy. 2016 Oct 2
9 24667653 Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol. 2014 May 25 1
10 23886934 Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: selectivity, kinetic characterization, and molecular modeling. 2013 Nov 1 1
11 24047137 Generation, validation, and application of a P450 homology model. 2013 2
12 20583320 Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage. 2011 Jan 1
13 19919601 Inhibition of procarcinogen-bioactivating human CYP1A1, CYP1A2 and CYP1B1 enzymes by melatonin. 2010 Jan 1
14 20609060 Inhibition of human liver microsomal CYP by nateglinide. 2010 May 1
15 19575443 Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices. 2009 Oct 15 1
16 17582584 Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or N-nitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. 2008 Mar 1
17 18497090 Phytoestrogens modulate the expression of 17alpha-estradiol metabolizing enzymes in cultured MCF-7 cells. 2008 1
18 17060372 Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1. 2007 Jan 1
19 17630984 An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. 2007 Aug 3
20 17959138 Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis. 2007 Dec 1 3
21 16226778 Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1. 2006 May 15 1
22 16528449 Silybin and dehydrosilybin inhibit cytochrome P450 1A1 catalytic activity: a study in human keratinocytes and human hepatoma cells. 2006 Mar 1
23 16719376 Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. 2006 2
24 17177569 Cytochrome P450 1A1 expression and activity in Caco-2 cells: modulation by apple juice extract and certain apple polyphenols. 2006 Dec 27 1
25 15766589 Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers. 2005 Apr 8 1
26 15958656 Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone. 2005 Sep 1
27 16120791 Modulation of human cytochrome P450 1B1 expression by 2,4,3',5'-tetramethoxystilbene. 2005 Dec 1
28 15182955 Differential regulation of CYP1A1 and CYP1B1 expression in resveratrol-treated human medulloblastoma cells. 2004 Jun 17 1
29 12495659 The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line. 2003 Jan 1
30 12670496 In vitro assessment of inhibition by natural polyphenols of metabolic activation of procarcinogens by human CYP1A1. 2003 Apr 11 1
31 12699690 Human CYP1A1 allelic variants: baculovirus expression and purification, hydrodynamic, spectral, and catalytical properties and their potency in the formation of all-trans-retinoic acid. 2003 Apr 4
32 12818727 Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. 2003 Jul 18 1
33 14637189 Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin. 2003 Dec 15 1
34 11950788 Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. 2002 May 1
35 12023534 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine. 2002 Jun 1
36 12391268 Cytochrome P450 CYP1A1 accumulates in the cytosol of kidney and brain and is activated by heme. 2002 Nov 1
37 11489750 Human lung microsomal cytochrome P4501A1 (CYP1A1) activities: impact of smoking status and CYP1A1, aryl hydrocarbon receptor, and glutathione S-transferase M1 genetic polymorphisms. 2001 Aug 1
38 11599655 Detailed characterization of experimentally derived human hepatic CYP1A1 activity and expression using differential inhibition of ethoxyresorufin O-deethylation by fluvoxamine. 2001 Aug 2
39 11701226 Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. 2001 Dec 15 1
40 11714871 Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. 2001 Dec 1
41 11048673 Further immunochemical and biocatalytic characterization of CYP1A1 from feral leaping mullet liver (Liza saliens) microsomes. 2000 Jul 1
42 11162432 Targeting of active human cytochrome P4501A1 (CYP1A1) to the periplasmic space of Escherichia coli. 2000 Dec 29 1
43 10503941 Neuronal nitric oxide synthase catalyzes the reduction of 7-ethoxyresorufin. 1999 2
44 10647906 Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. 1999 Dec 1
45 9820175 Potent and non-specific inhibition of cytochrome P450 by JM216, a new oral platinum agent. 1998 Nov 1
46 14577217 Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. 1998 1
47 9041675 Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line. 1997 Jan 1
48 9070254 In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility. 1997 Feb 3 1
49 9105404 Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole. 1997 Feb 21 1
50 9152602 Oxidation of xenobiotics by recombinant human cytochrome P450 1B1. 1997 May 2