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31776611 | Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure. | 2020 Jan |
3 |
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32730838 | Expression profile of cytochrome P450s and effects of polycyclic aromatic hydrocarbons and antiepileptic drugs on CYP1 expression in MOG-G-CCM cells. | 2020 Oct 1 |
5 |
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29980579 | Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 Induction. | 2018 Sep |
4 |
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28384415 | Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines. | 2017 Jun |
3 |
| 5 |
26970402 | Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor. | 2016 May 1 |
1 |
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26296470 | Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α. | 2015 Sep 25 |
6 |
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24663500 | Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells. | 2014 |
2 |
| 8 |
25112181 | Microfluidic geometric metering-based multi-reagent mixture generator for robust live cell screening array. | 2014 Dec |
4 |
| 9 |
23603339 | Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor. | 2013 May 25 |
1 |
| 10 |
23846855 | 3-methylcholanthrene induces neurotoxicity in developing neurons derived from human CD34+Thy1+ stem cells by activation of aryl hydrocarbon receptor. | 2013 Sep |
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| 11 |
24091107 | Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line. | 2013 Nov 25 |
3 |
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22673034 | Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers. | 2012 |
1 |
| 13 |
21666223 | Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures. | 2011 Sep |
1 |
| 14 |
20051482 | Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional activation of the CYP1A1 promoter. | 2010 Apr |
6 |
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20067464 | Augmentation of 3-methylcholanthrene-induced bioactivation in the human hepatoma cell line HepG2 by the calcium channel blocker nicardipine. | 2010 Mar |
2 |
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20350595 | Xenobiotic metabolism gene expression in the EpiDermin vitro 3D human epidermis model compared to human skin. | 2010 Aug |
1 |
| 17 |
20732958 | Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo. | 2010 Nov |
8 |
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19270430 | Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells. | 2009 Mar |
2 |
| 19 |
19280519 | Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells. | 2009 Mar |
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| 20 |
19336894 | Differentiation of monkey embryonic stem cells into hepatocytes and mRNA expression of cytochrome p450 enzymes responsible for drug metabolism: comparison of embryoid body formation conditions and matrices. | 2009 Apr |
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| 21 |
19465936 | Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells. | 2009 Jul 16 |
2 |
| 22 |
18502397 | Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements. | 2008 Jul 1 |
3 |
| 23 |
18559486 | Blood monocyte-derived neohepatocytes as in vitro test system for drug metabolism. | 2008 Sep |
1 |
| 24 |
17276403 | 3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells. | 2007 Mar 23 |
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| 25 |
16191477 | Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand. | 2006 Jan |
2 |
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16868070 | Cytochrome p450 expression of cultured rat small hepatocytes after long-term cryopreservation. | 2006 Oct |
1 |
| 27 |
16968971 | Novel functional association of serine palmitoyltransferase subunit 1-A peptide in sphingolipid metabolism with cytochrome P4501A1 transactivation and proliferative capacity of the human Glioma LN18 brain tumor cell line. | 2006 Sep |
4 |
| 28 |
15585370 | Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha. | 2005 Jan 15 |
1 |
| 29 |
15860653 | Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population. | 2005 Aug |
1 |
| 30 |
16137816 | PPARalpha activation potentiates AhR-induced CYP1A1 expression. | 2005 Dec 15 |
3 |
| 31 |
16167840 | Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2. | 2005 Sep |
4 |
| 32 |
16202979 | CYP1A1-mediated mechanism for atherosclerosis induced by polycyclic aromatic hydrocarbons. | 2005 Nov 18 |
3 |
| 33 |
16393856 | CCAAT/enhancer binding protein activation by PD98059 contributes to the inhibition of AhR-mediated 3-methylcholanthrene induction of CYP1A1. | 2005 Oct-Nov |
7 |
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14672759 | Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells. | 2004 Jan 9 |
2 |
| 35 |
14993811 | Polycyclic aromatic hydrocarbon increases mRNA level for interleukin 1 beta in human fibroblast-like synoviocyte line via aryl hydrocarbon receptor. | 2004 Mar |
1 |
| 36 |
15325265 | Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor. | 2004 Sep 17 |
3 |
| 37 |
15331414 | Near completely humanized liver in mice shows human-type metabolic responses to drugs. | 2004 Sep |
1 |
| 38 |
12490585 | Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic trioxide on CYP1A1 induction by polycyclic aromatic hydrocarbons. | 2003 Jan |
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| 39 |
12604190 | Transient induction of increased aldehyde dehydrogenase 3A1 levels in cultured human breast (adeno)carcinoma cell lines via 5'-upstream xenobiotic, and electrophile, responsive elements is, respectively, estrogen receptor-dependent and -independent. | 2003 Feb 1 |
1 |
| 40 |
12642474 | Thalidomide-induced suppression of embryo fibroblast proliferation requires CYP1A1-mediated activation. | 2003 Apr |
1 |
| 41 |
12941938 | Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation. | 2003 Nov 7 |
8 |
| 42 |
12237110 | Serum increases CYP1A1 induction by 3-methylcholanthrene. | 2002 Sep 20 |
4 |
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11231298 | Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2. | 2001 Mar |
1 |
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11324719 | Serum induces a transcriptional activation of CYP1A1 gene in HepG2 independently of the AhR pathway. | 2001 Mar 23 |
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| 45 |
11513080 | Establishment of a human hepatocyte line (OUMS-29) having CYP 1A1 and 1A2 activities from fetal liver tissue by transfection of SV40 LT. | 2001 May |
1 |
| 46 |
11698172 | Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544. | 2001 Dec |
1 |
| 47 |
10631103 | Induction of CYP1A1 by serum independent of AhR pathway. | 2000 Jan 19 |
1 |
| 48 |
10799337 | Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells. | 2000 May 1 |
2 |
| 49 |
10859152 | Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. | 2000 Jul |
1 |
| 50 |
10445394 | Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells. | 1999 Jul |
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