Polychlorinated Biphenyls

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







29 Article(s)
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1 24926919 Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. 2014 Aug 6
2 25299844 Endocrine disruption in human placenta: expression of the dioxin-inducible enzyme, CYP1A1, is correlated with that of thyroid hormone-regulated genes. 2014 Dec 1
3 23785672 Genetic polymorphisms in CYP1A1, CYP1B1 and COMT genes in Greenlandic Inuit and Europeans. 2013 1
4 22521609 EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes. 2012 Jun 1 2
5 21258071 Structural basis of species differences between human and experimental animal CYP1A1s in metabolism of 3,3',4,4',5-pentachlorobiphenyl. 2011 Apr 1
6 21540284 Individual polychlorinated biphenyl (PCB) congeners produce tissue- and gene-specific effects on thyroid hormone signaling during development. 2011 Jul 4
7 20819910 Analysis of the CYP1A1 mRNA dose-response in human keratinocytes indicates that relative potencies of dioxins, furans, and PCBs are species and congener specific. 2010 Dec 1
8 19514916 Weight of evidence evaluation of potential human cancer risks from exposure to polychlorinated biphenyls: an update based on studies published since 2003. 2009 1
9 17912254 AH receptor agonist activity in human blood measured with a cell-based bioassay: evidence for naturally occurring AH receptor ligands in vivo. 2008 Jul 2
10 18222549 Cytochrome P4501A1 expression, polychlorinated biphenyls and hydroxylated metabolites, and adipocyte size of bottlenose dolphins from the Southeast United States. 2008 Feb 18 1
11 18583386 Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls. 2008 Nov 1
12 18786521 Coplanar polychlorinated biphenyl-induced CYP1A1 is regulated through caveolae signaling in vascular endothelial cells. 2008 Nov 25 3
13 21783860 CYP1A1 and MT1K are congener specific biomarker genes for liver diseases induced by PCBs. 2008 Mar 1
14 17512696 Polychlorinated biphenyl exposure and CYP19 gene regulation in testicular and adrenocortical cell lines. 2007 Sep 1
15 18025053 Polychlorinated biphenyls alter the expression of endothelial nitric oxide synthase mRNA in human umbilical vein endothelial cells. 2007 Oct 1
16 16291828 AhR-agonist-induced transcriptional changes of genes involved in thyroid function in primary porcine thyrocytes. 2006 Feb 2
17 16580705 Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions. 2006 May 2
18 17051818 Induced CYP1A2 activity as a phenotypic biomarker in humans highly exposed to certain PCBs/PCDFs. 2006 Oct 1 1
19 15642161 Polychlorinated biphenyls, cytochrome P450 1A1 (CYP1A1) polymorphisms, and breast cancer risk among African American women and white women in North Carolina: a population-based case-control study. 2005 2
20 15915151 Complementary DNA cloning and constitutive expression of cytochrome P450 1C1 in the gills of carp (Cyprinus carpio). 2005 2
21 15583370 Serum polychlorinated biphenyls, cytochrome P-450 1A1 polymorphisms, and risk of breast cancer in Connecticut women. 2004 Dec 15 4
22 15750580 Isolation of cDNA of novel cytochrome P450 1B gene, CYP1B2, from Carp (Cyprinus carpio) and its induced expression in gills. 2004 2
23 12055053 Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Québec. 2002 Jun 3
24 12423652 Induction of cytochrome P450 1B1 in MDA-MB-231 human breast cancer cells by non-ortho-substituted polychlorinated biphenyls. 2002 Dec 1
25 12496044 Polychlorinated biphenyls, cytochrome P450 1A1, and breast cancer risk in the Nurses' Health Study. 2002 Dec 4
26 11054538 A cytochrome P4501B gene from a fish, Pleuronectes platessa. 2000 Oct 3 1
27 9950238 Polychlorinated biphenyls, cytochrome P4501A1 polymorphism, and postmenopausal breast cancer risk. 1999 Jan 4
28 10403516 Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1. 1999 Jul 1 6
29 7992230 Comparison of DNA adduct levels in human placenta from polychlorinated biphenyl exposed women and smokers in which CYP 1A1 levels are similarly elevated. 1994 2