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34474468 | Perspective of structural flexibility on selective inhibition towards CYP1B1 over CYP1A1 by α-naphthoflavone analogs. | 2021 Sep 22 |
3 |
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32060993 | Inhibition of human CYP1 enzymes by a classical inhibitor α-naphthoflavone and a novel inhibitor N-(3, 5-dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study. | 2020 May |
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| 3 |
30971064 | Particulate Matter-Induced Aryl Hydrocarbon Receptor Regulates Autophagy in Keratinocytes. | 2019 Apr 11 |
2 |
| 4 |
31203411 | Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells. | 2019 Jul |
2 |
| 5 |
28834568 | Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon-contaminated soils. | 2018 Feb |
1 |
| 6 |
29332599 | The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells. | 2018 |
2 |
| 7 |
30010034 | Transplacental transfer and metabolism of diuron in human placenta. | 2018 Oct 1 |
2 |
| 8 |
28103884 | Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation. | 2017 Jan 19 |
1 |
| 9 |
27113703 | The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity. | 2016 Jun 24 |
1 |
| 10 |
22749133 | The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. | 2013 Feb |
1 |
| 11 |
23033491 | Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder. | 2013 Jan |
2 |
| 12 |
23452206 | Cigarette smoke condensate extracts induce IL-1-beta production from rheumatoid arthritis patient-derived synoviocytes, but not osteoarthritis patient-derived synoviocytes, through aryl hydrocarbon receptor-dependent NF-kappa-B activation and novel NF-kappa-B sites. | 2013 Jun |
1 |
| 13 |
23508959 | Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism. | 2013 May 3 |
1 |
| 14 |
22837390 | Vitamin D receptor activation enhances benzo[a]pyrene metabolism via CYP1A1 expression in macrophages. | 2012 Nov |
1 |
| 15 |
21127131 | Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. | 2011 Mar |
1 |
| 16 |
21244437 | Inhibition of cytochrome P450 2A participating in coumarin 7-hydroxylation in pig liver microsomes. | 2011 Oct |
1 |
| 17 |
21726170 | In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450. | 2011 Nov |
1 |
| 18 |
20187624 | 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively. | 2010 Mar 15 |
1 |
| 19 |
20435083 | Cytochromes P4501 (CYP1): catalytic activities and inducibility by diesel exhaust particle extract and benzo[a]pyrene in intact human lung ex vivo. | 2010 Jun 29 |
1 |
| 20 |
20550209 | Metabolites of galangin by 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P450 1A1 in human intestinal epithelial Caco-2 cells and their antagonistic activity toward aryl hydrocarbon receptor. | 2010 Jul 14 |
2 |
| 21 |
21162728 | Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells. | 2010 Dec 16 |
1 |
| 22 |
19386251 | Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes. | 2009 Apr 30 |
2 |
| 23 |
19553035 | PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities. | 2009 Sep 10 |
2 |
| 24 |
19789301 | UVR exposure sensitizes keratinocytes to DNA adduct formation. | 2009 Oct |
1 |
| 25 |
18059023 | Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells. | 2008 Apr 1 |
2 |
| 26 |
18065768 | Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells. | 2008 Mar 1 |
1 |
| 27 |
15766918 | Molecular cloning and functional analysis of cytochrome P450 1A2 from Japanese monkey liver: comparison with marmoset cytochrome P450 1A2. | 2005 Feb 28 |
1 |
| 28 |
14962508 | A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin polychlorinated biphenyl126 and estrogen in human bronchial epithelial cells. | 2004 Feb 15 |
4 |
| 29 |
15081398 | Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages. | 2004 May 7 |
1 |
| 30 |
12495659 | The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line. | 2003 Jan |
1 |
| 31 |
12023534 | 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine. | 2002 Jun |
3 |
| 32 |
12127040 | Benzo(a)pyrene exposure induces CYP1A1 activity and expression in human endometrial cells. | 2002 May |
3 |
| 33 |
12147246 | Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone. | 2002 Aug 9 |
2 |
| 34 |
11768231 | Aryl hydrocarbon receptor/dioxin receptor in human monocytes and macrophages. | 2001 Oct |
1 |
| 35 |
10875683 | Identification of cytochrome P450 isoform involved in the metabolism of YM992, a novel selective serotonin re-uptake inhibitor, in human liver microsomes. | 2000 May |
1 |
| 36 |
10964100 | Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue. | 2000 Sep |
1 |
| 37 |
11082432 | Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes. | 2000 Dec |
1 |
| 38 |
9890552 | Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor. | 1999 Feb 1 |
1 |
| 39 |
10473105 | Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1. | 1999 Aug |
1 |
| 40 |
10534316 | Catalysis of drug oxidation during embryogenesis in human hepatic tissues using imipramine as a model substrate. | 1999 Nov |
1 |
| 41 |
9418899 | Constitutive activation of the aromatic hydrocarbon receptor. | 1998 Jan |
1 |
| 42 |
9774143 | Decreased expression of gamma-glutamyltranspeptidase in the intestinal cell line Caco-2 by inducers of cytochrome P450 1A1. | 1998 Oct 1 |
1 |
| 43 |
9089421 | Biotransformation of mestranol to ethinyl estradiol in vitro: the role of cytochrome P-450 2C9 and metabolic inhibitors. | 1997 Mar |
1 |
| 44 |
9093392 | Mutagenicity of the atmospheric transformation products 2-nitrofluoranthene and 2-nitrodibenzopyranone in Salmonella and human cell forward mutation assays. | 1997 Mar 17 |
2 |
| 45 |
9105404 | Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole. | 1997 Feb 21 |
1 |
| 46 |
9169082 | Carbaryl induces CYP1A1 gene expression in HepG2 and HaCaT cells but is not a ligand of the human hepatic Ah receptor. | 1997 May |
1 |
| 47 |
9223567 | Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites. | 1997 Jul |
1 |
| 48 |
8759031 | Atypical cytochrome P450 induction profiles in glomerular mesangial cells at the mRNA and enzyme level. Evidence for CYP1A1 and CYP1B1 expression and their involvement in benzo[a]pyrene metabolism. | 1996 Aug 23 |
2 |
| 49 |
8818577 | Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine. | 1996 Jul |
1 |
| 50 |
7554063 | p53 protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell lines. | 1995 Sep |
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