Polycyclic Aromatic Hydrocarbons

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







213 Article(s)
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151 11600727 Urinary 1-hydroxypyrene in coke oven workers relative to exposure, alcohol consumption, and metabolic enzymes. 2001 Nov 1
152 11675150 CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people. 2001 Dec 10 1
153 11689007 Human aryl hydrocarbon receptor polymorphisms that result in loss of CYP1A1 induction. 2001 Nov 9 1
154 11694458 Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression. 2001 Oct 2
155 23889309 Benzo(a)pyrene diolepoxide adducts to albumin in workers exposed to polycyclic aromatic hydrocarbons: association with specific CYP1A1, GSTM1, GSTP1 and EHPX genotypes. 2001 1
156 10631103 Induction of CYP1A1 by serum independent of AhR pathway. 2000 Jan 19 1
157 10651994 Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1. 2000 Feb 1
158 10698483 Association between polycyclic aromatic hydrocarbon-DNA adduct levels in maternal and newborn white blood cells and glutathione S-transferase P1 and CYP1A1 polymorphisms. 2000 Feb 1
159 10706104 Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor. 2000 Feb 15 2
160 10753202 CYP1A1 and GSTM1 polymorphisms affect urinary 1-hydroxypyrene levels after PAH exposure. 2000 Apr 1
161 10797280 Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers. 2000 Jun 1 3
162 11037803 Relation between inducibility of CYP1A1, GSTM1 and lung cancer in a French population. 2000 Oct 4
163 11062177 Interindividual variation in CYP1A1 expression in breast tissue and the role of genetic polymorphism. 2000 Nov 4
164 11113705 Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1. 2000 Dec 20 1
165 11465078 Drug-metabolizing enzymes: mechanisms and functions. 2000 Sep 2
166 11996099 Phenobarbital-induced expression of cytochrome P450 genes. 2000 1
167 9950238 Polychlorinated biphenyls, cytochrome P4501A1 polymorphism, and postmenopausal breast cancer risk. 1999 Jan 2
168 10331078 Induction of cytochrome P4501A1. 1999 1
169 10408872 Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers. 1999 May 2
170 10427467 Drug interactions with tobacco smoking. An update. 1999 Jun 1
171 10443949 Meat, metabolic genotypes and risk for colorectal cancer. 1999 Jul 1
172 10491856 [Role of metabolic polymorphisms in lung carcinogenesis]. 1999 Apr 6
173 10575002 The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism. 1999 Dec 3 2
174 9488590 Urinary excretion of 1-hydroxypyrene as a marker for exposure to urban air levels of polycyclic aromatic hydrocarbons. 1998 Feb 1
175 9538942 Cell-specific differences in the susceptibility of potential cellular targets of human origin derived from blood and lung following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 1998 Feb 2
176 9622076 Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism. 1998 Jun 1 2
177 9639391 Localization of CYP1A1 mRNA in human lung by in situ hybridization: comparison with immunohistochemical findings. 1998 Jul 3 2
178 9744530 Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture. 1998 Aug 2
179 9744534 Polycyclic aromatic hydrocarbon-DNA adducts in human placenta and modulation by CYP1A1 induction and genotype. 1998 Aug 1
180 9752993 Cytochrome P450 1A1 MspI polymorphism and urinary 1-hydroxypyrene concentrations in coke-oven workers. 1998 Sep 1
181 10026994 Impact of adduct determination on the assessment of cancer susceptibility. 1998 1
182 8970185 Relationship between plasma concentrations of beta-carotene and alpha-tocopherol and life-style factors and levels of DNA adducts in lymphocytes. 1997 3
183 9224217 Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers. 1997 Jul 3
184 8579379 Liver microsomal levels of cytochrome P450IA1 as biomarker for exposure and bioavailability of soil-bound polycyclic aromatic hydrocarbons. 1996 Jan 3
185 8631128 Autoregulation of human CYP1A1 gene promotor activity in HepG2 and MCF-7 cells. 1996 Mar 1
186 8666157 Cytochromes P450 5: induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription. 1996 Jun 1
187 8729008 Nuclear transcription factor Oct-1 binds to the 5'-upstream region of CYP1A1 and negatively regulates its expression. 1996 Feb 1
188 8824276 Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor. 1996 Oct 18 1
189 8860004 Distribution of composite CYP1A1 genotypes in Africans, African-Americans and Caucasians. 1996 May-Jun 2
190 8954573 Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1A1: a CO flash photolysis study. 1996 Dec 15 3
191 7546226 The impact of glutathione s-transferase M1 and cytochrome P450 1A1 genotypes on white-blood-cell polycyclic aromatic hydrocarbon-DNA adduct levels in humans. 1995 Sep 2
192 7581496 Metabolic polymorphism affecting DNA binding and excretion of carcinogens in humans. 1995 1
193 7581497 Cytochrome P450 mediated reactions studied in genetically engineered V79 Chinese hamster cells. 1995 1
194 7627950 Cytochrome P4501A1 and glutathione S-transferase (M1) genetic polymorphisms and postmenopausal breast cancer risk. 1995 Aug 15 3
195 7663528 Genetic polymorphism of induction of CYP1A1 (EROD) activity. 1995 Apr 2
196 7742722 CYP1A1 messenger RNA levels in placental tissue as a biomarker of environmental exposure. 1995 Mar 1
197 7788860 Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes. 1995 Jun 1
198 8830563 [Susceptibility to bronchial cancer: an example of genetic-environmental interaction]. 1995 1
199 20650112 Induction of Cytochrome P4501A1 in Haemopoietic Stem Cells by Hydroxylated Metabolites of Benzene. 1995 Aug 2
200 7737047 Pharmacogenetics: detecting sensitive populations. 1994 Dec 1