pyrene

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







15 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35307418 Insights into the hepatotoxicity of pyrene and 1-chloropyrene using an integrated approach of metabolomics and transcriptomics. 2022 Jul 10 1
2 30776468 CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance. 2019 Apr 1 1
3 31687396 Effects of Pyrene on Human Liver HepG2 Cells: Cytotoxicity, Oxidative Stress, and Transcriptomic Changes in Xenobiotic Metabolizing Enzymes and Inflammatory Markers with Protection Trial Using Lycopene. 2019 1
4 29471073 The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. 2018 Apr 1 1
5 30248327 Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene. 2018 Dec 1
6 25638374 Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5. 2014 1
7 17237483 Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation. 2007 Mar 1
8 15016593 Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene. 2004 Mar 3
9 12624000 CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs. 2003 Mar 1
10 12107646 Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. 2002 Jun 2
11 10825386 A repressive cross-regulation between catalytic and promoter activities of the CYP1A1 and CYP2E1 genes: role of H(2)O(2). 2000 Jun 1
12 7516235 1462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent. 1994 Feb 1
13 7808430 Transforming growth factor-beta 1 down-regulates basal and polycyclic aromatic hydrocarbon-induced cytochromes P-450 1A1 and 1A2 in adult human hepatocytes in primary culture. 1994 Dec 1
14 8170947 Inhibition of cytochromes P4501A by nitric oxide. 1994 Apr 26 1
15 2989797 Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism. 1985 Jun 25 1