Copper

prion protein ; Mus musculus







59 Article(s)
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1 35000151 The E3 Ubiquitin Ligase TRAF6 Interacts with the Cellular Prion Protein and Modulates Its Solubility and Recruitment to Cytoplasmic p62/SQSTM1-Positive Aggresome-Like Structures. 2022 Mar 1
2 35038117 Metal Ions Bound to Prion Protein Affect its Interaction with Plasminogen Activation System. 2022 Feb 2
3 34281567 Mutation of copper binding sites on cellular prion protein abolishes its inhibitory action on NMDA receptors in mouse hippocampal neurons. 2021 Jul 19 4
4 31726043 Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice. 2020 Jan 15 3
5 31814573 Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics. 2020 6
6 30636622 Oxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets? 2019 1
7 30729399 Copper Binding Regulates Cellular Prion Protein Function. 2019 Sep 1
8 29723291 Prion protein protects mice from lethal infection with influenza A viruses. 2018 May 2
9 30222366 Roles of Prion Protein in Virus Infections. 2018 Oct 1
10 30359282 Differential modulation of NMDA and AMPA receptors by cellular prion protein and copper ions. 2018 Oct 25 1
11 28413194 Dual role of cellular prion protein in normal host and Alzheimer's disease. 2017 1
12 24247244 A new paradigm for enzymatic control of α-cleavage and β-cleavage of the prion protein. 2014 Jan 10 1
13 22861352 Prion protein expression and functional importance in developmental angiogenesis: role in oxidative stress and copper homeostasis. 2013 Feb 1 3
14 23478311 Prion protein regulates iron transport by functioning as a ferrireductase. 2013 1
15 24141197 Mammalian Prion protein expression in yeast; a model for transmembrane insertion. 2013 Nov-Dec 1
16 22198568 Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease. 2012 Mar 4
17 22762267 Endogenous cellular prion protein regulates contractility of the mouse ileum. 2012 Sep 1
18 21264406 Prion protein expression level alters regional copper, iron and zinc content in the mouse brain. 2011 Feb 6
19 21265952 Cellular prion protein promotes glucose uptake through the Fyn-HIF-2α-Glut1 pathway to support colorectal cancer cell survival. 2011 Feb 1
20 20070537 Consequences of dietary manganese and copper imbalance on neuronal apoptosis in a murine model of scrapie. 2010 Jun 1
21 19597535 PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site. 2009 Sep 1
22 19635464 Role of copper and manganese in prion disease progression. 2009 Oct 6 7
23 18073096 Physiological role of the cellular prion protein. 2008 Jul-Aug 3
24 18332141 Manganese binding to the prion protein. 2008 May 9 1
25 18336352 Normal cytochrome C oxidase activity in prion protein gene-deficient mice. 2008 1
26 18406463 Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly. 2008 Jun 1
27 18717736 Involvement of glypican-1 autoprocessing in scrapie infection. 2008 Sep 2
28 18847486 Re-partitioning of Cu and Zn isotopes by modified protein expression. 2008 Oct 10 2
29 16517717 Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus. 2006 Mar 15 6
30 16924141 Bovine spongiform encephalopathy in Japan: history and recent studies on oxidative stress in prion diseases. 2006 1
31 15896301 Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival. 2005 Jun 24 2
32 16280605 Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein. 2005 3
33 15467011 Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App. 2004 Dec 15 1
34 15476389 Preventing misfolding of the prion protein by trimethylamine N-oxide. 2004 Oct 19 1
35 12429022 Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein. 2003 Feb 15 4
36 12500977 Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. 2003 Mar 14 7
37 12558968 Tethering the N-terminus of the prion protein compromises the cellular response to oxidative stress. 2003 Feb 1
38 12861388 Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform. 2003 Jun 11
39 12878182 Expression of normal cellular prion protein (PrP(c)) on T lymphocytes and the effect of copper ion: Analysis by wild-type and prion protein gene-deficient mice. 2003 Aug 8 2
40 12893277 Absence of superoxide dismutase activity in a soluble cellular isoform of prion protein produced by baculovirus expression system. 2003 Aug 1 1
41 14522849 Putative functions of PrP(C). 2003 8
42 14597699 NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. 2003 Nov 11 1
43 14622132 Modulation of L-type voltage-gated calcium channels by recombinant prion protein. 2003 Nov 2
44 11698407 Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting. 2002 Jan 18 2
45 11829763 Metal imbalance and compromised antioxidant function are early changes in prion disease. 2002 Feb 15 2
46 11145979 Antioxidant activity related to copper binding of native prion protein. 2001 Jan 3
47 11278539 Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform. 2001 Apr 6 2
48 11323744 Insights into the physiological function of cellular prion protein. 2001 May 1
49 11413003 Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region. 2001 Apr 3 1
50 11730893 Prion diseases: copper deficiency states associated with impaired nitrogen monoxide or carbon monoxide transduction and translocation. 2001 Dec 1 1