| 1 |
35132941 | Synthesis, molecular docking, molecular dynamics and evaluation of Drug-Likeness properties of the fused N-Formyl pyrazoline substituted new dehydroepiandrosterone derivatives. | 2022 Feb 8 |
1 |
| 2 |
32888176 | Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4. | 2021 Feb |
1 |
| 3 |
33400885 | The regulation of liver cytochrome P450 expression and activity by the brain serotonergic system in different experimental models. | 2021 Apr |
2 |
| 4 |
33809117 | Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies. | 2021 Mar 12 |
1 |
| 5 |
34563259 | The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis. | 2021 Sep 26 |
1 |
| 6 |
34867397 | Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis. | 2021 |
2 |
| 7 |
33252269 | Association of ABCB1 and CYP450 Gene Polymorphisms and their DNA Methylation Status with Steroid-Induced Osteonecrosis of the Femoral Head in the Chinese Population. | 2020 Dec |
1 |
| 8 |
28668640 | Spectroscopic studies of the cytochrome P450 reaction mechanisms. | 2018 Jan |
1 |
| 9 |
29069987 | In vitro fertilization-frozen embryo transfer in a patient with cytochrome P450 oxidoreductase deficiency: a case report. | 2018 May |
1 |
| 10 |
30607725 | A New Method for Quantitative Determination of Steroid Metabolites of Cytochrome P450-Dependent Reactions Using Fluorescent Spectroscopy. | 2018 Nov |
1 |
| 11 |
28344492 | CYP2C9, CYPC19 and CYP2D6 gene profiles and gene susceptibility to drug response and toxicity in Turkish population. | 2017 Mar |
2 |
| 12 |
28731962 | Polymorphisms in cytochrome P450 oxidoreductase and its effect on drug metabolism and efficacy. | 2017 Sep |
2 |
| 13 |
26658226 | Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes. | 2016 Feb |
2 |
| 14 |
27267697 | Recent Structural Insights into Cytochrome P450 Function. | 2016 Aug |
1 |
| 15 |
23474437 | Cytochrome P450-mediated metabolic alterations in preeclampsia evaluated by quantitative steroid signatures. | 2014 Jan |
4 |
| 16 |
24642534 | NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells. | 2014 |
3 |
| 17 |
23587001 | Conformational diversity and ligand tunnels of mammalian cytochrome P450s. | 2013 Jan-Feb |
2 |
| 18 |
23632015 | New trends in cytochrome p450 research at the half-century mark. | 2013 Jun 14 |
1 |
| 19 |
23851904 | GC-MS-based quantitative signatures of cytochrome P450-mediated steroid oxidation induced by rifampicin. | 2013 Aug |
4 |
| 20 |
22687469 | Diversity and substrate specificity in the structures of steroidogenic cytochrome P450 enzymes. | 2012 |
3 |
| 21 |
23092891 | P450 oxidoreductase deficiency: a disorder of steroidogenesis with multiple clinical manifestations. | 2012 Oct 23 |
1 |
| 22 |
21193036 | The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension. | 2011 May |
1 |
| 23 |
21763268 | C-26 vs. C-27 hydroxylation of insect steroid hormones: regioselectivity of a microsomal cytochrome P450 from a hormone-resistant cell line. | 2011 Sep 1 |
2 |
| 24 |
20218941 | The effects of cytochrome P450 induction by xenobiotics on endobiotic metabolism in pre-clinical safety studies. | 2010 May |
1 |
| 25 |
20844025 | Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. | 2010 Dec |
2 |
| 26 |
21226440 | Dapsone-associated methaemoglobinaemia in patients with a haematologic malignancy. | 2010 Nov |
1 |
| 27 |
19324859 | Expression of cytochrome P450 (CYP) enzymes in human nonpigmented ciliary epithelial cells: induction of CYP1B1 expression by TCDD. | 2009 Jul |
2 |
| 28 |
19473111 | Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications. | 2009 Jun |
6 |
| 29 |
18388875 | Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism. | 2008 Jun |
2 |
| 30 |
18646550 | Cytochrome P450 polymorphism--molecular, metabolic, and pharmacogenetic aspects. II. Participation of CYP isoenzymes in the metabolism of endogenous substances and drugs. | 2008 May-Jun |
2 |
| 31 |
18955142 | Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes. | 2008 Dec |
2 |
| 32 |
17253801 | Regioselective oxyfunctionalization of unactivated carbons in steroids by a model of cytochrome P-450: osmiumporphyrin complex/tert-butyl hydroperoxide system. | 2007 Feb 2 |
1 |
| 33 |
17786620 | Ronald Estabrook's early guidance of a postdoctoral fellow concerning the intricacies of steroid metabolism by cytochromes P450. | 2007 |
1 |
| 34 |
15608133 | Cytochrome P450-mediated oxidation of glucuronide derivatives: example of estradiol-17beta-glucuronide oxidation to 2-hydroxy-estradiol-17beta-glucuronide by CYP 2C8. | 2005 Mar |
1 |
| 35 |
15876406 | New assumptions about oxidative processes involved in steroid hormone biosynthesis: is the role of cytochrome P-450-activated dioxygen limited to hydroxylation reactions or are dioxygen insertion reactions also possible? | 2005 Apr |
1 |
| 36 |
16143297 | Steroid hydroxylations: a paradigm for cytochrome P450 catalyzed mammalian monooxygenation reactions. | 2005 Dec 9 |
1 |
| 37 |
16183271 | A thiolate ligand on a cytochrome P-450 mimic permits the use of simple environmentally benign oxidants for biomimetic steroid hydroxylation in water. | 2005 Dec 15 |
1 |
| 38 |
16922637 | The influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms. | 2005 Aug |
1 |
| 39 |
15135080 | Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes. | 2004 Apr 15 |
2 |
| 40 |
15237850 | Cytochrome P450: what have we learned and what are the future issues? | 2004 May |
1 |
| 41 |
15356430 | Urinary tract diseases revealed after DTP vaccination in infants and young children: cytokine irregularities and down-regulation of cytochrome P-450 enzymes induced by the vaccine may uncover latent diseases in genetically predisposed subjects. | 2004 Sep-Oct |
1 |
| 42 |
15543094 | Possible pathomechanisms of sudden infant death syndrome: key role of chronic hypoxia, infection/inflammation states, cytokine irregularities, and metabolic trauma in genetically predisposed infants. | 2004 Nov-Dec |
1 |
| 43 |
15644946 | Cytochrome p450 enzymes and cardiovascular disease. | 2004 Dec |
2 |
| 44 |
15669763 | Biomimetic oxidation of unactivated carbons in steroids by a model of cytochrome P-450, oxorutheniumporphyrinate complex. | 2004 Sep |
2 |
| 45 |
11869873 | Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. | 2002 Apr |
1 |
| 46 |
12126389 | Catalytic oxidations of steroid substrates by artificial cytochrome p-450 enzymes. | 2002 Jul 26 |
1 |
| 47 |
12171873 | Differential effect of IFNalpha-2b on the cytochrome P450 enzyme system: a potential basis of IFN toxicity and its modulation by other drugs. | 2002 Aug |
2 |
| 48 |
12374776 | Testosterone, cytochrome P450, and cardiac hypertrophy. | 2002 Oct |
1 |
| 49 |
12452431 | Rate-limiting steps in cytochrome P450 catalysis. | 2002 Oct |
1 |
| 50 |
12664659 | [The role of nuclear receptors in cytochrome P-450 induction by xenochemicals]. | 2002 |
1 |