Heme

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







117 Article(s)
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51 10926165 Use of recombinant human ferrochelatase as a sensitive bioassay for N-alkylprotoporphyrin IX formed after interaction of porphyrinogenic xenobiotics with rat liver microsomes. 2000 Jul 2
52 10460168 Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation. 1999 Aug 24 1
53 9721336 Interactions between nitric oxide and cytochrome P-450 in the liver. 1998 Jul 2
54 9817620 Differences in interactions of SSRIs. 1998 Sep 2
55 9526800 Molecular mechanism of heme biosynthesis. 1997 Oct 3
56 8634277 X-ray diffraction analysis of cytochrome P450 2B4 reconstituted into liposomes. 1996 Feb 6 1
57 8942676 Role of the polarity of the heme environment for the CO stretch modes in cytochrome P-450cam-CO. 1996 Nov 26 1
58 7539291 Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue. 1995 May 30 1
59 7588807 Compressibility of the heme pocket of substrate analogue complexes of cytochrome P-450cam-CO. The effect of hydrostatic pressure on the Soret band. 1995 Oct 15 1
60 15299332 Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3). 1995 Jan 1 1
61 7532811 Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole. 1994 Nov 1
62 8291131 [Reduction of cytochrome p-450 content and activity by porphyrins after damage to the microsomal membrane by tetrachloromethane]. 1993 May-Jun 1
63 1425665 Heme-pocket-hydration change during the inactivation of cytochrome P-450camphor by hydrostatic pressure. 1992 Oct 15 1
64 1521541 Cytochrome P-450 induction in human lung tumor-derived cell lines. Characterisation and effects of inflammatory mediators. 1992 Sep 1 1
65 1650250 Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron. 1991 Jul 12 1
66 1965943 The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces changes in the heme spin state of microsomal cytochrome P-450. 1990 Dec 1
67 2223769 The cytochrome P-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling. 1990 Aug 14 1
68 2298305 Heme maintains catalytically active structure of cytochrome P-450. 1990 Jan 29 2
69 2344452 [The role of heme in formation of the native structure of cytochrome P-450 LM2]. 1990 Jan 2
70 2496984 On the role of phospholipids in the reconstituted cytochrome P-450 system. A model study using dilauroyl and distearoyl glycerophosphocholine. 1989 May 1 1
71 2519716 Covalent bonding of the prosthetic heme to protein: a potential mechanism for the suicide inactivation or activation of hemoproteins. 1989 May-Jun 1
72 2753040 Rapid partial degradation of DDT by a cytochrome P-450 model system. 1989 Jul 1 1
73 2914926 19F nuclear magnetic resonance as a probe of the spatial relationship between the heme iron of cytochrome P-450 and its substrate. 1989 Feb 15 2
74 2848247 Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells. 1988 Dec 1
75 3044903 Disruption of hepatic heme biosynthesis after interaction of xenobiotics with cytochrome P-450. 1988 Sep 7
76 3039980 Inhibition of cytochrome P-450-linked monooxygenase systems by naphthoquinones. 1987 Jul 31 1
77 3489441 Increased rat testicular heme oxygenase activity associated with depressed microsomal heme and cytochrome P-450 levels after repeated administration of human chorionic gonadotropin. 1986 Sep 1
78 3539534 Control of 5-aminolevulinate synthase in animals. 1986 3
79 3697359 Conformational change of cytochrome P-450 indicated by the measurement of fluorescence-energy transfer. 1986 Apr 22 1
80 3955002 Ligand and halide binding properties of chloroperoxidase: peroxidase-type active site heme environment with cytochrome P-450 type endogenous axial ligand and spectroscopic properties. 1986 Jan 28 1
81 3964273 Amino terminal sequence analysis of human placenta aromatase. 1986 Mar 28 1
82 2409076 Chemical reactivities of bleomycin. 1985 Jul 5 1
83 2990535 Decreased lipid order induced by microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in model membranes: fluorescence and electron spin resonance studies. 1985 Jun 4 1
84 3972828 Branchpoint for heme alkylation and metabolite formation in the oxidation of arylacetylenes by cytochrome P-450. 1985 Mar 25 1
85 4039724 Inhibition of testicular cytochrome P-450-dependent steroid biosynthesis by cis-platinum. Reversal by human chorionic gonadotropin. 1985 May 25 1
86 6378529 New developments in the regulation of heme metabolism and their implications. 1984 1
87 6548701 Control of heme and cytochrome P-450 metabolism by inorganic metals, organometals and synthetic metalloporphyrins. 1984 Aug 1
88 6595992 Different pathways of chloroform metabolism. 1984 1
89 6185486 Mössbauer study of iron bleomycin and its activation intermediates. 1983 Feb 10 2
90 6418502 Glutathione and hepatic mixed-function oxidase activity. 1983 1
91 6617864 Effect of succinylacetone on heme and cytochrome P450 synthesis in hepatocyte culture. 1983 Mar 21 1
92 6639949 Circular dichroism studies of low-spin ferric cytochrome P-450CAM ligand complexes. 1983 Nov 14 2
93 6833253 Stereochemistry of cytochrome P-450-catalyzed epoxidation and prosthetic heme alkylation. 1983 Apr 10 2
94 6848512 Chiral orientation of prosthetic heme in the cytochrome P-450 active site. 1983 Jan 10 5
95 6954546 The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology. 1982 Apr 1
96 7107639 Endogenous cysteine ligation in ferric and ferrous cytochrome P-450. Direct evidence from x-ray absorption spectroscopy. 1982 Sep 25 1
97 7171721 Absorption spectra of highly purified liver microsomal cytochrome P-450 in non-equilibrium conformational states at low temperatures. 1982 2
98 6894611 Potent heme-degrading action of antimony and antimony-containing parasiticidal agents. 1981 Feb 1 1
99 6897891 Enzymatic basis of metal ion alterations of cellular heme and glutathione metabolism. 1981 Sep-Oct 2
100 7217086 Destruction of cytochrome P-450 by ethylene. Structure of the resulting prosthetic heme adduct. 1981 May 10 2