| 1 |
35408976 | Molecular Lego of Human Cytochrome P450: The Key Role of Heme Domain Flexibility for the Activity of the Chimeric Proteins. | 2022 Mar 25 |
2 |
| 2 |
31919943 | A Modified Arrhenius Approach to Thermodynamically Study Regioselectivity in Cytochrome P450-Catalyzed Substrate Conversion. | 2020 May 15 |
1 |
| 3 |
31956764 | Lipophilic Metabolic Efficiency (LipMetE) and Drug Efficiency Indices to Explore the Metabolic Properties of the Substrates of Selected Cytochrome P450 Isoforms. | 2020 Jan 14 |
2 |
| 4 |
32515070 | The Fe-N-C Nanozyme with Both Accelerated and Inhibited Biocatalytic Activities Capable of Accessing Drug-Drug Interactions. | 2020 Aug 17 |
3 |
| 5 |
30399481 | Investigation on drug-binding in heme pocket of CYP2C19 with UV-visible and resonance Raman spectroscopies. | 2019 Feb 15 |
3 |
| 6 |
30499388 | Biology of Heme: Drug Interactions and Adverse Drug Reactions with CYP450. | 2019 |
1 |
| 7 |
30633519 | Cytochrome P450-The Wonderful Nanomachine Revealed through Dynamic Simulations of the Catalytic Cycle. | 2019 Feb 19 |
1 |
| 8 |
27875967 | Microbial P450 Enzymes in Bioremediation and Drug Discovery: Emerging Potentials and Challenges. | 2018 |
1 |
| 9 |
29530595 | CW EPR parameters reveal cytochrome P450 ligand binding modes. | 2018 Jun |
2 |
| 10 |
28104494 | Thoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands. | 2017 Jul |
1 |
| 11 |
28919040 | Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. | 2017 Oct 19 |
1 |
| 12 |
28960974 | A Chemoproteomic Platform To Assess Bioactivation Potential of Drugs. | 2017 Oct 16 |
1 |
| 13 |
29024391 | Orthogonal Expression of an Artificial Metalloenzyme for Abiotic Catalysis. | 2017 Dec 14 |
1 |
| 14 |
29053951 | Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. | 2017 Oct 19 |
1 |
| 15 |
29143058 | Membrane environment drives cytochrome P450's spin transition and its interaction with cytochrome b5. | 2017 Nov 28 |
2 |
| 16 |
27245908 | Assay of Endocannabinoid Oxidation by Cytochrome P450. | 2016 |
1 |
| 17 |
26042637 | Manganese Catalyzed C-H Halogenation. | 2015 Jun 16 |
1 |
| 18 |
26181717 | The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation. | 2015 |
1 |
| 19 |
24523110 | Multienzyme kinetics and sequential metabolism. | 2014 |
1 |
| 20 |
24618756 | From cholesterogenesis to steroidogenesis: role of riboflavin and flavoenzymes in the biosynthesis of vitamin D. | 2014 Mar 1 |
2 |
| 21 |
24956138 | Hydroxylated derivatives of NPC1161: theoretical insights into their potential toxicity and the feasibility and regioselectivity of their formation. | 2014 Jul 24 |
1 |
| 22 |
23514038 | Mapping a disordered portion of the Brz2001-binding site on a plant monooxygenase, DWARF4, using a quartz-crystal microbalance biosensor-based T7 phage display. | 2013 Apr |
1 |
| 23 |
24207099 | Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells. | 2013 Nov 8 |
2 |
| 24 |
24233717 | Iron(IV)hydroxide pK(a) and the role of thiolate ligation in C-H bond activation by cytochrome P450. | 2013 Nov 15 |
1 |
| 25 |
24312617 | Identifying cytochrome p450 functional networks and their allosteric regulatory elements. | 2013 |
2 |
| 26 |
22087535 | Comparative study of the affinity and metabolism of type I and type II binding quinoline carboxamide analogues by cytochrome P450 3A4. | 2012 Jan 12 |
2 |
| 27 |
22197672 | Prediction of sites of metabolism in a substrate molecule, instanced by carbamazepine oxidation by CYP3A4. | 2012 Jan 15 |
1 |
| 28 |
23174983 | An N-bridged high-valent diiron-oxo species on a porphyrin platform that can oxidize methane. | 2012 Dec |
1 |
| 29 |
20860521 | Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal. | 2011 Feb |
1 |
| 30 |
20606811 | Ethanol-induced oxidative stress: basic knowledge. | 2010 Jun |
1 |
| 31 |
20967245 | Cytochrome P450 reductase: a harbinger of diffusible reduced oxygen species. | 2010 Oct 13 |
1 |
| 32 |
19414330 | Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. | 2009 Mar |
1 |
| 33 |
19708688 | Kinetics and activation parameters for oxidations of styrene by Compounds I from the cytochrome P450(BM-3) (CYP102A1) heme domain and from CYP119. | 2009 Sep 29 |
2 |
| 34 |
18311908 | Characterization of type II ligands in CYP2C9 and CYP3A4. | 2008 Mar 27 |
3 |
| 35 |
18855665 | Cytochrome P450-activated prodrugs: targeted drug delivery. | 2008 |
2 |
| 36 |
19040121 | Detection of cytochrome P450-2A6, -3A5 and -4B1 with real-time polymerase chain reaction in prostate tissue. | 2008 Sep-Oct |
2 |
| 37 |
17504219 | Expression and function of cytochrome p450 in brain drug metabolism. | 2007 May |
2 |
| 38 |
17225875 | CYP2D6 polymorphisms in patients with porphyrias. | 2006 Sep-Oct |
1 |
| 39 |
15854816 | Cytochrome P450 biosensors-a review. | 2005 Jun 15 |
2 |
| 40 |
16833677 | Electronic ground states of iron porphyrin and of the first species in the catalytic reaction cycle of cytochrome P450s. | 2005 Apr 21 |
1 |
| 41 |
15102545 | 57 varieties: the human cytochromes P450. | 2004 Apr |
2 |
| 42 |
12966104 | Evidence that dioxygen and substrate activation are tightly coupled in dopamine beta-monooxygenase. Implications for the reactive oxygen species. | 2003 Dec 12 |
1 |
| 43 |
12135382 | Regioselective peroxo-dependent heme alkylation in P450(BM3)-F87G by aromatic aldehydes: effects of alkylation on cataysis. | 2002 Jul 30 |
1 |
| 44 |
12437345 | Molecular mechanism of the electron transfer reaction in cytochrome P450(cam)--putidaredoxin: roles of glutamine 360 at the heme proximal site. | 2002 Nov 26 |
1 |
| 45 |
12487729 | Comparison of rat and human cytochrome P450 (CYP) sources of N-alkylprotoporphyrin IX. Formation after interaction with porphyrinogenic xenobiotics: studies with cDNA-expressed single CYP enzymes. | 2002 Nov |
2 |
| 46 |
11240372 | The optical interconversion of the P-450 and P-420 forms of neuronal nitric oxide synthase: effects of sodium cholate, mercury chloride and urea. | 2001 Feb |
1 |
| 47 |
11427068 | Monooxygenation mechanism by cytochrome p-450. | 2001 Jul 4 |
3 |
| 48 |
11669629 | Covalent linkage of prosthetic heme to CYP4 family P450 enzymes. | 2001 Oct 30 |
1 |
| 49 |
10601869 | Assignment of heme methyl 1H-NMR resonances of high-spin and low-spin ferric complexes of cytochrome p450cam using one-dimensional and two-dimensional paramagnetic signals enhancement (PASE) magnetization transfer experiments. | 2000 Jan |
3 |
| 50 |
10773020 | Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity. | 2000 May |
1 |