Clopidogrel

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







48 Article(s)
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Pub. Year
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1 34410044 Translational aspects of cytochrome P450-mediated drug-drug interactions: A case study with clopidogrel. 2022 Jan 2
2 32338045 Influences of Smoking Status on Effectiveness of Cytochrome P450 Enzyme System Metabolized Medications in Reducing In-Hospital Death in 14 658 Patients With Acute Myocardial Infarction: Data From CPACS-3 Study. 2020 Sep 1
3 30936195 Pharmacogenomic considerations for antiplatelet agents: the era of precision medicine in stroke prevention and neurointerventional practice. 2019 Apr 2
4 30998396 Clopidogrel Pharmacogenetics. 2019 Apr 2
5 31418753 Smoking and cardiovascular diseases: paradox greater than expected? 2019 Oct 30 2
6 27637911 Concomitant Use of Proton-Pump Inhibitors and Clopidogrel Increases the Risk of Adverse Outcomes in Patients With Ischemic Stroke Carrying Reduced-Function CYP2C19*2. 2018 Jan 2
7 29449127 Evaluating the Effect of Six Proton Pump Inhibitors on the Antiplatelet Effects of Clopidogrel. 2018 Jun 3
8 29496531 Effects of Danshen capsules on the pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers. 2018 Sep 2
9 29858511 Cytochrome P450 genotype-guided drug therapies: An update on current states. 2018 Oct 2
10 26633836 Effects of dabigatran on the cellular and protein phase of coagulation in patients with coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel. Results from a prospective, randomised, double-blind, placebo-controlled study. 2016 Mar 2
11 26961113 Association of Cytochrome P450 Genetic Variants with Clopidogrel Resistance and Outcomes in Acute Ischemic Stroke. 2016 Oct 1 1
12 27239927 [The possibility of selecting optimal antiplatelet therapy in patients with coronary heart disease in terms of CYP2C19 polymorphism]. 2016 1
13 25666703 New insight into the mechanisms of gastroduodenal injury induced by nonsteroidal anti-inflammatory drugs: practical implications. 2015 1
14 26220948 Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel. 2015 Oct 1
15 26639695 Pharmacogenetic testing in population of South Ural. 2015 3
16 24500235 Prasugrel and ticagrelor: is there a winner? 2014 Jan 2
17 24762860 Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated patients after acute myocardial infarction. 2014 Jun 4
18 24803100 Interaction of clopidogrel and statins in secondary prevention after cerebral ischaemia - a randomized, double-blind, double-dummy crossover study. 2014 Nov 2
19 23149816 Clinical impact of genetically determined platelet reactivity. 2013 Jun 3
20 23480885 [Genetic variability in the efficacy of clopidogrel]. 2013 Mar 11 2
21 23770199 Hepatocellular toxicity of clopidogrel: mechanisms and risk factors. 2013 Dec 2
22 23903277 [Statin and clopidogrel pharmacological interaction]. 2013 Sep 4
23 24378836 Genetic and nongenetic factors influencing the response to clopidogrel. 2013 Dec 4
24 24378837 Potential clinical utility of genetic and platelet function tests in patients on treatment with clopidogrel. 2013 Dec 4
25 22568693 Comparative pharmacokinetics and pharmacodynamics of platelet adenosine diphosphate receptor antagonists and their clinical implications. 2012 Jul 1 4
26 22589111 Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis. 2012 Apr 1
27 20845077 Cytochrome P450 2C19 polymorphism is associated with poor clinical outcomes in coronary artery disease patients treated with clopidogrel. 2011 Mar 2
28 20980920 The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity. 2011 Jan 2
29 21251580 Calcium-channel blockers do not alter the clinical efficacy of clopidogrel after myocardial infarction: a nationwide cohort study. 2011 Jan 25 1
30 21352268 Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions? 2011 Oct 3
31 21392639 Clopidogrel-drug interactions. 2011 Mar 15 5
32 21546883 The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors. 2011 2
33 21771377 [Interaction between clopidogrel and proton pump inhibitors]. 2011 2
34 21826477 Thienopyridine-associated drug-drug interactions: pharmacologic mechanisms and clinical relevance. 2011 Oct 1
35 19904241 Proton pump inhibitor and clopidogrel interaction: fact or fiction? 2010 Jan 3
36 19919843 Impact of genetic and acquired alteration in cytochrome P450 system on pharmacologic and clinical response to clopidogrel. 2010 Feb 5
37 20180610 Genetic causes of clopidogrel nonresponsiveness: which ones really count? 2010 Mar 2
38 20735423 Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. 2010 Sep 3
39 19106084 Cytochrome p-450 polymorphisms and response to clopidogrel. 2009 Jan 22 3
40 19337788 Frequency of CYP3A4, CYP3A5, CYP2C9, and CYP2C19 variant alleles in patients receiving clopidogrel that experience repeat acute coronary syndrome. 2009 Mar 2
41 19414633 Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes. 2009 May 19 2
42 19576320 Relation of genetic polymorphisms in the cytochrome P450 gene with clopidogrel resistance after drug-eluting stent implantation in Koreans. 2009 Jul 1 4
43 18482659 Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. 2008 May 20 4
44 18687246 The association of cigarette smoking with enhanced platelet inhibition by clopidogrel. 2008 Aug 12 2
45 17900275 Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. 2007 Dec 2
46 16772608 Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. 2006 Oct 1 6
47 16011979 The inhibitory potency of clopidogrel on ADP-induced platelet activation is not attenuated when it is co-administered with atorvastatin (20 mg/day) for 5 weeks in patients with acute coronary syndromes. 2005 Aug 1
48 14522569 Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study. 2003 Oct 3