Testosterone

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







31 Article(s)
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1 32219694 In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions. 2020 Jun 2
2 32279279 The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions. 2020 Dec 1
3 32941854 Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy. 2020 Nov 1 1
4 29989011 Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes. 2018 Jul 1
5 27323294 Simultaneous evaluation of substrate-dependent CYP3A inhibition using a CYP3A probe substrates cocktail. 2016 Sep 1
6 25864949 A simple construction of electrochemical liver microsomal bioreactor for rapid drug metabolism and inhibition assays. 2015 2
7 26481538 Inhibition of human cytochrome P450 isoenzymes by a phenothiazine neuroleptic levomepromazine: An in vitro study. 2015 Dec 1
8 24117377 Cytochrome P450 modified polycrystalline indium tin oxide film as a drug metabolizing electrochemical biosensor with a simple configuration. 2013 Nov 5 1
9 22050110 Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer. 2012 Feb 2
10 22773874 Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4. 2012 Aug 24 1
11 19326769 Enzyme induction and cytotoxicity in human hepatocytes by chlorpyrifos and N,N-diethyl-m-toluamide (DEET). 2008 1
12 17936932 Human metabolic interactions of environmental chemicals. 2007 2
13 14630070 Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation. 2004 Feb 1
14 20945304 Human cytochrome P450: metabolism of testosterone by CYP3A4 and inhibition by ketoconazole. 2004 Jun 1
15 12936704 Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes. 2003 Aug 1
16 11037108 Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates. 2000 Aug 2
17 10460798 Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes. 1999 Sep 1
18 9616193 N-Dealkylation and hydroxylation of ebastine by human liver cytochrome P450. 1998 Jun 1
19 9820175 Potent and non-specific inhibition of cytochrome P450 by JM216, a new oral platinum agent. 1998 Nov 1
20 9353130 Drug metabolism in hepatocyte sandwich cultures of rats and humans. 1997 Oct 1 2
21 7627274 Young female patient with testosterone-producing adrenocortical adenoma also showing signs of subclinical Cushing's syndrome. 1995 Apr 1
22 1491046 Improved sample preparation for the testosterone hydroxylation assay using disposable extraction columns. 1992 Nov 6 2
23 2231265 Inhibition of testosterone biosynthesis in testicular microsomes by various imidazole drugs. Comparative study with ketoconazole. 1990 Jun 1
24 2328827 Testosterone lowers aromatase activity in cultured human genital skin fibroblasts. 1990 Mar 5 1
25 2848247 Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells. 1988 Dec 1
26 3129418 Novel properties of human placental aromatase as cytochrome P-450: purification and characterization of a unique form of aromatase. 1988 Jan 1
27 3429444 Purification of human liver cytochrome P-450 catalyzing testosterone 6 beta-hydroxylation. 1987 Sep 3
28 3493777 Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations. 1987 Feb 15 1
29 611643 The additive effects of progestins on testosterone-stimulated hepatic ethylmorphine metabolism and cytochrome P-450 content. 1977 Dec 1
30 1209686 Differential inhibition of androst-4-en-3,17-dione aromatization by carbon monoxide in the presence of estr-4-en-3,17-dione. 1975 Nov 1
31 4831127 Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism. 1974 Jun 1