| 1 |
31744669 | Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research. | 2020 Feb 5 |
1 |
| 2 |
31164617 | Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. | 2019 May 13 |
1 |
| 3 |
29989011 | Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes. | 2018 Jul |
1 |
| 4 |
27273149 | Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects. | 2017 Jan |
1 |
| 5 |
22483397 | High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma. | 2012 May 1 |
1 |
| 6 |
21198441 | An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS. | 2011 Jan |
1 |
| 7 |
21444768 | Understanding the determinants of selectivity in drug metabolism through modeling of dextromethorphan oxidation by cytochrome P450. | 2011 Apr 12 |
1 |
| 8 |
18634893 | Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds. | 2008 Nov-Dec |
1 |
| 9 |
17452028 | Simultaneous analysis of cytochrome P450 probes-dextromethorphan, flurbiprofen and midazolam and their major metabolites by HPLC-mass-spectrometry/fluorescence after single-step extraction from plasma. | 2007 Jun 15 |
1 |
| 10 |
11411376 | Pharmacological control of cough. | 2001 Apr |
1 |
| 11 |
11452704 | Lack of gender differences and large intrasubject variability in cytochrome P450 activity measured by phenotyping with dextromethorphan. | 2001 Jul |
1 |
| 12 |
10764440 | Drug interactions in palliative care. | 2000 Apr |
1 |
| 13 |
11013424 | High-throughput cytochrome P450 inhibition screening via cassette probe-dosing strategy. IV. Validation of a direct injection on-line guard cartridge extraction/tandem mass spectrometry method for simultaneous CYP3A4, 2D6 and 2E1 inhibition assessment. | 2000 |
2 |
| 14 |
11037108 | Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates. | 2000 Aug |
2 |
| 15 |
8861658 | Investigation of xenobiotic metabolism by CYP2D6 and CYP2C19: importance of enantioselective analytical methods. | 1996 Mar 29 |
1 |
| 16 |
8846618 | Antidepressant drug interactions and the cytochrome P450 system. The role of cytochrome P450 2D6. | 1995 |
2 |
| 17 |
1306804 | Cytochrome P450-dependent metabolism of dextromethorphan: fetal and adult studies. | 1992 |
1 |