Rifampin

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







52 Article(s)
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1 33547469 Fostemsavir: The first oral attachment inhibitor for treatment of HIV-1 infection. 2021 Feb 19 1
2 34143391 A Physiologically Based Pharmacokinetic and Drug-Drug Interaction Model for the CB2 Agonist Lenabasum. 2021 Jul 1
3 31656654 Effect of rifampicin and clarithromycin on the CYP3A activity in patients with Mycobacterium avium complex. 2019 Sep 1
4 28686070 Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. 2018 Jul 1
5 29143479 Encapsulation of rifampin in a polymeric layer-by-layer structure for drug delivery. 2018 Apr 4
6 29357810 Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells. 2018 2
7 28173639 Bosentan and Rifampin Interactions Modulate Influx Transporter and Cytochrome P450 Expression and Activities in Primary Human Hepatocytes. 2017 May 1 4
8 28215634 Isolation and expansion of human pluripotent stem cell-derived hepatic progenitor cells by growth factor defined serum-free culture conditions. 2017 Mar 15 1
9 27458223 Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects. 2016 Oct 1
10 27795624 Rifampicin and anti-hypertensive drugs in chronic kidney disease: Pharmacokinetic interactions and their clinical impact. 2016 Sep 3
11 25808545 Microbial-derived lithocholic acid and vitamin K2 drive the metabolic maturation of pluripotent stem cells-derived and fetal hepatocytes. 2015 Jul 1
12 23071008 Application of a substrate cocktail approach in the assessment of cytochrome P450 induction using cultured human hepatocytes. 2013 Feb 2
13 23770199 Hepatocellular toxicity of clopidogrel: mechanisms and risk factors. 2013 Dec 2
14 23851904 GC-MS-based quantitative signatures of cytochrome P450-mediated steroid oxidation induced by rifampicin. 2013 Aug 2
15 23974699 Chronological effects of rifampicin discontinuation on cytochrome P450 activity in healthy Japanese volunteers, using the cocktail method. 2013 Dec 1
16 24060875 Induction of influx and efflux transporters and cytochrome P450 3A4 in primary human hepatocytes by rifampin, rifabutin, and rifapentine. 2013 Dec 2
17 22236925 In vitro reaction phenotyping studies on rifamycins to explain the auto-induction of rifabutin metabolism. 2012 Feb 4
18 22617226 Effects of CYP induction by rifampicin on tamoxifen exposure. 2012 Jul 5
19 22676424 Rifampicin has a profound effect on the pharmacokinetics of oral S-ketamine and less on intravenous S-ketamine. 2012 Nov 2
20 22834478 In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective β3-adrenoceptor agonist. 2012 Dec 1
21 21047828 Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin. 2011 Jan 1
22 21210720 Hepatic differentiation of human embryonic stem cells is promoted by three-dimensional dynamic perfusion culture conditions. 2011 May 1
23 21508826 Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration. 2011 Jun 1
24 19468476 Tuberculosis in renal transplant recipients. 2008 Jul 1
25 17381666 Rifampin, a cytochrome P450 3A inducer, decreases plasma concentrations of antipsychotic risperidone in healthy volunteers. 2007 Apr 1
26 17181373 Tuberculosis and HIV co-infection: a practical therapeutic approach. 2006 1
27 16003296 Drug interaction between mycophenolate mofetil and rifampin: possible induction of uridine diphosphate-glucuronosyltransferase. 2005 Jul 2
28 14748817 Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects. 2004 Feb 2
29 15554232 Rifampicin, a keystone inducer of drug metabolism: from Herbert Remmer's pioneering ideas to modern concepts. 2004 Oct 1
30 14604466 Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin. 2003 Sep 4
31 11744607 Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin. 2002 Jan 1
32 12426514 Rifampin markedly decreases plasma concentrations of praziquantel in healthy volunteers. 2002 Nov 2
33 11327199 Delavirdine: clinical pharmacokinetics and drug interactions. 2001 2
34 11601668 Clinical implications of drug interactions with coxibs. 2001 Oct 1
35 11180018 Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. 2000 Dec 4
36 9454825 Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isozymes in human hepatocytes in primary culture. 1998 Feb 1
37 9871429 Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin. 1998 Dec 4
38 9353130 Drug metabolism in hepatocyte sandwich cultures of rats and humans. 1997 Oct 1 1
39 9385296 Update on rifampin drug interactions, III. 1997 Nov 24 1
40 9391787 Relationship between cytochrome P-450 induction by rifampicin, hepatic volume and portal blood flow in man. 1997 Oct 2
41 7636727 Rifampicin induction of lidocaine metabolism in cultured human hepatocytes. 1995 Aug 3
42 8049635 Lung tumor resection does not affect debrisoquine metabolism. 1994 Mar 1
43 1974199 Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450. 1990 May-Jun 1
44 2200675 Expression of cytochrome P-450 enzymes in cultured human hepatocytes. 1990 Jul 31 1
45 2565211 Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily. 1989 Mar-Apr 1
46 2682943 Interactions of cyclosporine with antimicrobial agents. 1989 Sep-Oct 1
47 2744145 [The immunotropic activity of GABA during cytochrome P-450 induction in the liver]. 1989 Mar-Apr 1
48 3608348 The effect of antipyrine and rifampin on the metabolism of diazepam. 1987 Aug 1
49 3665337 The mechanism of the warfarin-rifampin drug interaction in humans. 1987 Oct 1
50 6508979 Influence of rifampicin treatment on antipyrine clearance and metabolite formation in patients with tuberculosis. 1984 Nov 1