30 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35578608 | Delayed Acetaminophen Absorption Resulting in Acute Liver Failure. | 2022 | 1 |
2 | 30151903 | Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily-Dosing Model. | 2019 Jan | 8 |
3 | 31254976 | A computational model for hepatotoxicity by coupling drug transport and acetaminophen metabolism equations. | 2019 Sep | 5 |
4 | 30121710 | An insight into paracetamol and its metabolites using molecular docking and molecular dynamics simulation. | 2018 Aug 18 | 3 |
5 | 28951593 | MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity. | 2017 Sep 26 | 3 |
6 | 25658971 | Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction. | 2015 Mar 23 | 1 |
7 | 24949552 | Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices. | 2014 Sep 2 | 1 |
8 | 27147854 | Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose? | 2011 | 6 |
9 | 19219744 | Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes. | 2009 Jan | 3 |
10 | 18338302 | Acetaminophen-induced nephrotoxicity: pathophysiology, clinical manifestations, and management. | 2008 Mar | 1 |
11 | 17497828 | High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2007 Jun 15 | 1 |
12 | 15078344 | Characterization of the acetaminophen-induced degradation of cytochrome P450-3A4 and the proteolytic pathway. | 2004 Apr | 2 |
13 | 11866476 | Reduction of toxic metabolite formation of acetaminophen. | 2002 Mar 8 | 2 |
14 | 11377097 | Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology. | 2001 Jun | 1 |
15 | 9152386 | Catalysis of the cysteine conjugation and protein binding of acetaminophen by microsomes from a human lymphoblast line transfected with the cDNAs of various forms of human cytochrome P450. | 1997 May | 1 |
16 | 8877251 | Idiosyncratic drug reactions. Metabolic bioactivation as a pathogenic mechanism. | 1996 Sep | 2 |
17 | 8470644 | Acetaminophen hepatotoxicity: potentiation by isoniazid. | 1993 Apr | 2 |
18 | 1344831 | [Omeprazole and liver functions]. | 1992 Sep-Oct | 1 |
19 | 1461639 | [Alcohol and the liver: ethanol metabolism and the pathomechanism of alcoholic liver damage]. | 1992 Dec 13 | 1 |
20 | 1546013 | Recognizing acetaminophen hepatotoxicity in chronic alcoholics. | 1992 Mar | 1 |
21 | 2375760 | Isolation of four forms of acetone-induced cytochrome P-450 in chicken liver by h.p.l.c. and their enzymic characterization. | 1990 Jul 1 | 1 |
22 | 2519233 | A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism. | 1989 Jan-Feb | 3 |
23 | 2703963 | Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity. | 1989 Mar | 1 |
24 | 3181604 | The microsomal ethanol oxidizing system: its role in ethanol and xenobiotic metabolism. | 1988 Jun | 1 |
25 | 3342453 | Cytochrome P-450-mediated oxidation of substrates by electron-transfer; role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol. | 1988 | 1 |
26 | 3385648 | Drug metabolite toxicity assessed in human lymphocytes with a purified, reconstituted cytochrome P-450 system. | 1988 Jun | 1 |
27 | 2868861 | The mechanisms of cobalt chloride-induced protection against acetaminophen hepatotoxicity. | 1986 Jan-Feb | 2 |
28 | 3511825 | Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure. | 1986 Mar | 1 |
29 | 2983185 | Metabolic activation and toxicity of acetaminophen and related analogs. A theoretical study. | 1985 Mar | 1 |
30 | 183224 | Biochemical changes after hepatic injury from toxic doses of acetaminophen or furosemide. | 1976 | 1 |