Uridine Diphosphate Glucuronic Acid

UDP-glucose 6-dehydrogenase ; Homo sapiens







47 Article(s)
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1 32749901 Integration of Sugar Metabolism and Proteoglycan Synthesis by UDP-glucose Dehydrogenase. 2021 Jan 2
2 33572239 Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells. 2021 Feb 9 2
3 34548906 Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer. 2021 Sep 14 2
4 31932306 Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2-AS1. 2020 Mar 13 1
5 32001716 Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy. 2020 Jan 30 1
6 32175296 A Missense Mutation in the UGDH Gene Is Associated With Developmental Delay and Axial Hypotonia. 2020 2
7 32768525 UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells. 2020 Nov 1 2
8 30774864 Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy. 2019 Jan 1 2
9 31189734 Catalytic mechanism of UDP-glucose dehydrogenase. 2019 Jun 28 2
10 31243371 UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis. 2019 Jul 1
11 29324279 Inhibition of UDP-glucose dehydrogenase by 6-thiopurine and its oxidative metabolites: Possible mechanism for its interaction within the bilirubin excretion pathway and 6TP associated liver toxicity. 2018 Mar 20 1
12 29479058 Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration. 2018 May 1
13 30457329 Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core. 2018 Dec 18 2
14 26582015 Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase. 2016 Mar 1
15 27198584 Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking. 2016 Jun 7 2
16 27241161 Biosynthesis of Drug Glucuronide Metabolites in the Budding Yeast Saccharomyces cerevisiae. 2016 Jul 5 1
17 27307252 Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential. 2016 Aug 3
18 26190959 Enzymatic Redox Cascade for One-Pot Synthesis of Uridine 5'-Diphosphate Xylose from Uridine 5'-Diphosphate Glucose. 2014 Nov 24 1
19 23363239 Hysteresis and negative cooperativity in human UDP-glucose dehydrogenase. 2013 Feb 26 1
20 22123821 Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. 2012 Jan 13 2
21 22525098 Catalytic mechanism of human UDP-glucose 6-dehydrogenase: in situ proton NMR studies reveal that the C-5 hydrogen of UDP-glucose is not exchanged with bulk water during the enzymatic reaction. 2012 Jul 15 2
22 23106432 Cofactor binding triggers a molecular switch to allosterically activate human UDP-α-D-glucose 6-dehydrogenase. 2012 Nov 20 1
23 21502315 Structure and mechanism of human UDP-glucose 6-dehydrogenase. 2011 Jul 8 3
24 21576248 Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease. 2011 Jul 8 2
25 21602353 Structure of Burkholderia cepacia UDP-glucose dehydrogenase (UGD) BceC and role of Tyr10 in final hydrolysis of UGD thioester intermediate. 2011 Aug 4
26 21984906 Structural basis of cooperativity in human UDP-glucose dehydrogenase. 2011 2
27 19676054 Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer. 2010 Jan 15 1
28 20691680 Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells. 2010 Oct 15 3
29 20863317 UDP-glucose dehydrogenase: structure and function of a potential drug target. 2010 Oct 3
30 19244115 Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels. 2009 Mar 15 2
31 19358821 Computational analysis of the quaternary structural changes induced by point mutations in human UDP-glucose dehydrogenase. 2009 Jun 1 2
32 17209547 Characterization of human UDP-glucose dehydrogenase reveals critical catalytic roles for lysine 220 and aspartate 280. 2007 Jan 16 2
33 16495656 Identification of a cis-acting element responsible for negative regulation of the human UDP-glucose dehydrogenase gene expression. 2006 Feb 2
34 17073734 Expression, purification, crystallization, and preliminary X-Ray analysis of the human UDP-glucose dehydrogenase. 2006 2
35 16002992 Analysis of human UDP-glucose dehydrogenase gene promoter: identification of an Sp1 binding site crucial for the expression of the large transcript. 2005 Jun 2
36 16158268 Inhibition of human UDP-glucose dehydrogenase expression using siRNA expression vector in breast cancer cells. 2005 Aug 3
37 16292757 Effects of xenobiotics and peroxisome proliferator-activated receptor-alpha on the human UDPglucose dehydrogenase gene expression. 2005 2
38 15044486 Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations. 2004 May 28 3
39 15247292 Importance of Gly-13 for the coenzyme binding of human UDP-glucose dehydrogenase. 2004 Sep 3 2
40 12682078 Specific protein-1 is a universal regulator of UDP-glucose dehydrogenase expression: its positive involvement in transforming growth factor-beta signaling and inhibition in hypoxia. 2003 Jun 13 2
41 10973831 Human UDP-glucose dehydrogenase gene: complete cloning and transcription start mapping. 2000 Sep 7 2
42 9737970 Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes. 1998 Sep 25 3
43 7868856 Alterations in hyaluronan synthesis during developing joint cavitation. 1995 Mar 2
44 8220234 Serum stimulation of UDP-glucose dehydrogenase activity in Swiss 3T3 fibroblasts. 1993 Aug 1
45 8471533 Uridine diphosphoglucose dehydrogenase activity in normal and rheumatoid synovium: the description of a specialized synovial lining cell. 1993 Feb 2
46 2287590 The nature of cytoplasmic vacuoles in chordoma cells. A correlative enzyme and electron microscopic histochemical study. 1990 Oct 1
47 1023336 [Histochemical demonstration of uridine diphospho-glucoso-4'-epimerase activity]. 1976 2