Pentostatin

adenosine deaminase ; Homo sapiens







116 Article(s)
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51 2273300 Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells. 1990 Oct 4
52 2275794 Structural and conformational analysis of pentostatin (2'-deoxycoformycin), a potent inhibitor of adenosine deaminase. 1990 Aug 3
53 2291566 Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells. 1990 1
54 2316512 Effects of 2'-deoxycoformycin on HL-60 cell differentiation, adenosine deaminase, and oligoadenylate synthetase. 1990 Apr 1
55 2357554 Effects of adenosine deaminase inhibition on active uptake and metabolism of adenosine in astrocytes in primary cultures. 1990 May 7 1
56 2497184 Establishment and characterization of adenosine deaminase-deficient human T cell lines. 1989 Jun 1 1
57 2502523 Potentiation of growth-inhibitory activity of 9-beta-D-arabinofuranosyladenine by 2'-deoxycoformycin in human cultured cell lines derived from leukemias and lymphomas. 1989 May 3
58 2575348 Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. 1989 1
59 2783731 Pentostatin in the treatment of advanced hairy cell leukemia. 1989 Feb 4
60 2788175 The erythrocyte as instigator of inflammation. Generation of amidated C3 by erythrocyte adenosine deaminase. 1989 Aug 1
61 2812252 Inhibition of adenosine deaminase activity reveals an intense active transport of adenosine into neurons in primary cultures. 1989 Aug 1
62 2841534 Enzymes of purine metabolism in lymphoid neoplasms, clinical relevance for treatment with enzyme inhibitors. 1988 Jun 1 1
63 3257147 Opposite effects of recombinant interferon-alpha A and deoxycoformycin on adenosine deaminase activity in the Daudi B lymphoblastoid cell line. 1988 Jan 9
64 3258602 Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives. 1988 Apr 25 1
65 3260524 Endogenous and exogenous adenosine inhibit granulocyte aggregation without altering the associated rise in intracellular calcium concentration. 1988 Jul 1
66 3263401 Treatment of cutaneous T cell lymphoma with 2'-deoxycoformycin (pentostatin). 1988 Oct 1
67 3342099 Adenosine metabolism in human whole blood. Effects of nucleoside transport inhibitors and phosphate concentration. 1988 Feb 15 4
68 2890401 Membrane phenotype and response to deoxycoformycin in mature T cell malignancies. 1987 Oct 10 1
69 3332090 The role of pentostatin (2'-deoxycoformycin, dCF) in the management of lymphoproliferative malignancies. 1987 Jun 1
70 3829699 Adenosine deaminase in herpes simplex virus induced corneal stromal disease. 1987 Jan 6
71 2433905 The biochemical pharmacology of (2'-R)-chloropentostatin, a novel inhibitor of adenosine deaminase. 1986 3
72 2939873 Successful remission induction with deoxycoformycin in elderly patients with T-helper prolymphocytic leukaemia. 1986 May 1
73 3011239 Enzymes of purine metabolism in hairy cell leukemia. 1986 Jul 1 1
74 3486057 Energy metabolism in adenosine deaminase-inhibited human erythrocytes. 1986 Apr 15 1
75 3486414 Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells. 1986 May 1
76 3488805 Association of severe and fatal infections and treatment with pentostatin. 1986 Sep 2
77 2579098 Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. 1985 Feb 1
78 2981904 Biochemical enzyme analysis in acute leukaemia. 1985 Feb 1
79 3872599 Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency. 1985 Apr 1
80 3873908 Adenosine deaminase gene amplification in deoxycoformycin-resistant mammalian cells. 1985 Jun 1
81 3874406 Effects of adenosine deaminase inhibitor 2'-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to beta-araA. 1985 1
82 3875570 Differential antiproliferative actions of 2',5' oligo A trimer core and its cordycepin analogue on human tumor cells. 1985 Sep 15 1
83 3881043 Adenosine metabolism in human skin fibroblasts. 1985 Jan 4
84 6204981 In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA. 1984 Aug 10 1
85 6236916 Relative sensitivity of human T cell subsets to deoxyadenosine toxicity. 1984 Oct 1
86 6334522 Transport of deoxycoformycin in human erythrocytes. Measurement by adenosine deaminase titration and radioisotope assays. 1984 Dec 15 5
87 6334686 Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells. 1984 Dec 25 1
88 6424986 B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine. 1984 Apr 2
89 6607471 Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin. 1984 Jan 1
90 6609525 Adenosine deaminase in malaria infection: effect of 2'-deoxycoformycin in vivo. 1984 1
91 6609531 Deoxycoformycin resistant mammalian cells that overproduce adenosine deaminase. 1984 1
92 6610419 An enzymatic kinetic method for the determination of 2'-deoxycoformycin in biological fluids. 1984 May 15 4
93 6610485 The mechanism of inhibition and "reversal" of mitogen-induced lymphocyte activation in a model of adenosine deaminase deficiency. 1984 Jul 1
94 6303563 Characterization of an adenosine deaminase-deficient human histiocytic lymphoma cell line (DHL-9) and selection of mutants deficient in adenosir kinase and deoxycytidine kinase. 1983 Jun 1
95 6311934 Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. 1983 Oct 1 1
96 6414755 Importance of platelet-free preparations for evaluating lymphocyte nucleotide levels in inherited or acquired immunodeficiency syndromes. 1983 Dec 1
97 6600401 An investigation of 2'-deoxycoformycin in the treatment of cutaneous T-cell lymphoma. 1983 Feb 4
98 6601986 S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine. 1983 Jul 2
99 6283540 Mechanism of deoxyadenosine-induced catabolism of adenine ribonucleotides in adenosine deaminase-inhibited human T lymphoblastoid cells. 1982 Apr 2
100 6289941 Biochemical correlates of the differential sensitivity of subtypes of human leukemia to deoxyadenosine and deoxycoformycin. 1982 Nov 1