Tretinoin

aldehyde dehydrogenase 1 family member A1 ; Homo sapiens







71 Article(s)
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1 35056791 Novel Disulfiram Derivatives as ALDH1a1-Selective Inhibitors. 2022 Jan 12 2
2 35078784 Targeting S100A9-ALDH1A1-Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer. 2022 Apr 1 1
3 35213790 Evidence of depot-specific regulation of all-trans-retinoic acid biosynthesis in human adipose tissue. 2022 Jun 2
4 35412614 Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma. 2022 Apr 12 1
5 35574006 Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis. 2022 1
6 33355213 Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver. 2021 Mar 6
7 33495566 PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling. 2021 Jan 25 3
8 33550205 Exploitation of the vitamin A/retinoic acid axis depletes ALDH1-positive cancer stem cells and re-sensitises resistant non-small cell lung cancer cells to cisplatin. 2021 Apr 1
9 33744437 Development of new disulfiram analogues as ALDH1a1-selective inhibitors. 2021 May 15 1
10 34120916 Role and Mechanism of Vitamin A Metabolism in the Pathophysiology of Parkinson's Disease. 2021 1
11 31187490 ALDH1A1 in patient-derived bladder cancer spheroids activates retinoic acid signaling leading to TUBB3 overexpression and tumor progression. 2020 Feb 15 6
12 32293355 All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells. 2020 Apr 15 9
13 32695508 ALDH1 Cancer Stem Cell Marker as a Prognostic Factor in Triple-Negative Breast Cancer. 2020 1
14 33132350 Ginger Increases ALDH1A1 Expression and Enhances Retinoic Acid Signaling in a Human Colonic Epithelial Cell Line. 2020 4
15 29948941 Multifaceted Regulation of ALDH1A1 by Cdk5 in Alzheimer's Disease Pathogenesis. 2019 Feb 2
16 30292490 Expression of retinoic acid signaling components ADH7 and ALDH1A1 is reduced in aniridia limbal epithelial cells and a siRNA primary cell based aniridia model. 2019 Feb 2
17 30709378 Correction to: Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells. 2019 Feb 1 1
18 30733805 Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells. 2019 1
19 30166520 High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling. 2018 Aug 30 2
20 30409702 Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. 2018 Dec 1 2
21 30541574 Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells. 2018 Dec 12 2
22 28087752 Deficient retinoid-driven angiogenesis may contribute to failure of adult human lung regeneration in emphysema. 2017 Jun 1
23 28423611 The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells. 2017 Apr 4 1
24 28677722 Regulation of retinoic acid synthetic enzymes by WT1 and HDAC inhibitors in 293 cells. 2017 Sep 2
25 28783931 Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction? 2017 Aug 31 3
26 27107124 Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus. 2016 Jul 1 6
27 27157616 All-trans retinoic acid targets gastric cancer stem cells and inhibits patient-derived gastric carcinoma tumor growth. 2016 Oct 27 1
28 27443528 Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines. 2016 Sep 1
29 27724856 Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma. 2016 Oct 10 3
30 24285572 Deficient expression of aldehyde dehydrogenase 1A1 is consistent with increased sensitivity of Gorlin syndrome patients to radiation carcinogenesis. 2015 Jun 2
31 25427913 Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers. 2015 1
32 25502770 Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations. 2015 Feb 2
33 25742746 All-trans retinoic acid downregulates ALDH1-mediated stemness and inhibits tumour formation in ovarian cancer cells. 2015 Apr 4
34 25793304 Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. 2015 1
35 26305673 Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression. 2015 Sep 29 1
36 24374552 Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival. 2014 Apr 3
37 24524833 Levels of the retinoic acid synthesizing enzyme aldehyde dehydrogenase-1A2 are lower in testicular tissue from men with infertility. 2014 Apr 1
38 24594504 Aldehyde dehydrogenase 1A1: friend or foe to female metabolism? 2014 Mar 3 1
39 24887554 Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium. 2014 May 27 1
40 25230277 NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. 2014 Dec 15 2
41 23236537 Downregulation of ALDH1A1 expression in non-small cell lung carcinomas--its clinicopathologic and biological significance. 2013 1
42 23614737 Targeting ALDH1A1 to treat pigmentary disorders. 2013 May 1
43 23957476 Development and validation of a 96-well cellular assay for the discovery of ALDH1A1 inhibitors. 2013 Jul 1
44 24080087 Aldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations. 2013 Dec 2
45 21704731 The contribution of vitamin A to autocrine regulation of fat depots. 2012 Jan 2
46 23254580 Eradication of hepatitis C virus subgenomic replicon by interferon results in aberrant retinol-related protein expression. 2012 1
47 21436255 Concerted action of aldehyde dehydrogenases influences depot-specific fat formation. 2011 May 2
48 21514413 Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas. 2011 May 3
49 21674038 Retinoic Acid signalling and the control of meiotic entry in the human fetal gonad. 2011 1
50 18992716 Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction. 2009 Jan 15 6