| 1 |
31969989 | The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. | 2020 |
1 |
| 2 |
26336957 | Influence of metabolic syndrome factors and insulin resistance on the efficacy of ezetimibe/simvastatin and atorvastatin in patients with metabolic syndrome and atherosclerotic coronary heart disease risk. | 2015 Sep 4 |
1 |
| 3 |
24855368 | Effects of extended-release niacin/laropiprant, simvastatin, and the combination on correlations between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients with dyslipidemia. | 2014 |
1 |
| 4 |
23100282 | Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study. | 2013 Apr |
2 |
| 5 |
23866306 | Consistency of effect of ezetimibe/simvastatin compared with intensified lipid-lowering treatment strategies in obese and non-obese diabetic subjects. | 2013 Jul 16 |
2 |
| 6 |
23880197 | Effects of ezetimibe, simvastatin and ezetimibe/simvastatin on correlations between apolipoprotein B, LDL cholesterol and non-HDL cholesterol in patients with primary hypercholesterolemia. | 2013 Aug |
1 |
| 7 |
23890516 | Age, abdominal obesity, and baseline high-sensitivity C-reactive protein are associated with low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B responses to ezetimibe/simvastatin and atorvastatin in patients with metabolic syndrome. | 2013 Jul-Aug |
1 |
| 8 |
24092915 | The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA₂. | 2013 Dec |
4 |
| 9 |
23166513 | RHOA is a modulator of the cholesterol-lowering effects of statin. | 2012 |
1 |
| 10 |
20345493 | Effect of moderate and high-dose simvastatin on asymmetric dimethylarginine-homocysteine metabolic pathways in patients with newly detected severe hypercholesterolemia. | 2011 Oct |
1 |
| 11 |
21349260 | Switching from statin monotherapy to ezetimibe/simvastatin or rosuvastatin modifies the relationships between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients at high risk of coronary disease. | 2011 Jun |
2 |
| 12 |
21859750 | Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome. | 2011 Oct |
1 |
| 13 |
20142117 | Efficacy of simvastatin or ezetimibe on tissue factor, von Willebrand's factor and C-reactive protein in patients with hypercholesterolaemia. | 2010 Jan |
1 |
| 14 |
20413733 | Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin. | 2010 Jul |
1 |
| 15 |
20461472 | Influence of simvastatin on apoB-100 secretion in non-obese subjects with mild hypercholesterolemia. | 2010 Jun |
2 |
| 16 |
20529243 | Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects. | 2010 Jun 7 |
1 |
| 17 |
21029821 | Safety and efficacy of ezetimibe/simvastatin combination versus atorvastatin alone in adults ≥65 years of age with hypercholesterolemia and with or at moderately high/high risk for coronary heart disease (the VYTELD study). | 2010 Nov 1 |
1 |
| 18 |
19305020 | Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia. | 2009 Jul |
3 |
| 19 |
19327776 | Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL). | 2009 Aug |
1 |
| 20 |
19332196 | Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy. | 2009 Apr |
1 |
| 21 |
19539078 | Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study). | 2009 Jun 15 |
1 |
| 22 |
19618992 | Effects of simvastatin and carnitine versus simvastatin on lipoprotein(a) and apoprotein(a) in type 2 diabetes mellitus. | 2009 Aug |
1 |
| 23 |
19660610 | Correlation of non-high-density lipoprotein cholesterol and low-density lipoprotein cholesterol with apolipoprotein B during simvastatin + fenofibrate therapy in patients with combined hyperlipidemia (a subanalysis of the SAFARI trial). | 2009 Aug 15 |
6 |
| 24 |
18669979 | VAP II analysis of lipoprotein subclasses in mixed hyperlipidemic patients on treatment with ezetimibe/simvastatin and fenofibrate. | 2008 Dec |
1 |
| 25 |
18957124 | Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study. | 2008 Oct 28 |
1 |
| 26 |
17109866 | Effects of fenofibrate and simvastatin on HDL-related biomarkers in low-HDL patients. | 2007 Dec |
1 |
| 27 |
17318708 | One-month therapy with simvastatin restores endothelial function in hypercholesterolemic children and adolescents. | 2007 Jan-Feb |
1 |
| 28 |
16005883 | Proportion of oxidized LDL relative to plasma apolipoprotein B does not change during statin therapy in patients with heterozygous familial hypercholesterolemia. | 2006 Apr |
1 |
| 29 |
16545796 | Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis. | 2006 Mar 27 |
1 |
| 30 |
17022864 | Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. | 2006 Oct |
1 |
| 31 |
15642080 | Efficacy and safety of ezetimibe co-administered with simvastatin in thiazolidinedione-treated type 2 diabetic patients. | 2005 Jan |
1 |
| 32 |
16162940 | Treatment with high-dose simvastatin reduces secretion of apolipoprotein B-lipoproteins in patients with diabetic dyslipidemia. | 2005 Dec |
2 |
| 33 |
15110130 | Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: A multicenter, randomized, double-blind, placebo-controlled trial. | 2004 Mar |
1 |
| 34 |
15132403 | Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial. | 2004 May |
1 |
| 35 |
15265253 | Effectiveness of simvastatin therapy in raising HDL-C in patients with type 2 diabetes and low HDL-C. | 2004 Jul |
1 |
| 36 |
12686335 | Effects of adding fenofibrate (200 mg/day) to simvastatin (10 mg/day) in patients with combined hyperlipidemia and metabolic syndrome. | 2003 Apr 15 |
3 |
| 37 |
12901521 | The influence of apolipoprotein B and E gene polymorphisms on the response to simvastatin therapy in patients with hyperlipidemia. | 2003 Mar |
2 |
| 38 |
12119202 | Influence of atorvastatin and simvastatin on apolipoprotein B metabolism in moderate combined hyperlipidemic subjects with low VLDL and LDL fractional clearance rates. | 2002 Sep |
7 |
| 39 |
12153549 | Effect of Simvastatin on markers of triglyceride-rich lipoproteins in familial hypercholesterolaemia. | 2002 Jul |
3 |
| 40 |
12390953 | Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized, double-blind, placebo-controlled trial with simvastatin. | 2002 Oct 22 |
2 |
| 41 |
12404199 | Simvastatin, transdermal patch, and oral estrogen-progestogen preparation in early-postmenopausal hypercholesterolemic women: a randomized, placebo-controlled clinical trial. | 2002 Nov |
2 |
| 42 |
11427209 | Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells. | 2001 Jul |
1 |
| 43 |
11902822 | Adrenocorticotrophic hormone exerts marked lipid-lowering effects in simvastatin-treated patients. | 2001 Dec |
1 |
| 44 |
10217372 | Plasma lipoprotein distribution and lipid transfer activities in patients with type IIb hyperlipidemia treated with simvastatin. | 1999 Apr |
1 |
| 45 |
10357840 | Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin. | 1999 Jun |
1 |
| 46 |
10432174 | Effects of simvastatin on fasting and postprandial triglyceride-rich lipoproteins in patients with type I diabetes mellitus. | 1999 Mar-Apr |
1 |
| 47 |
10525131 | The rebound of lipoproteins after LDL-apheresis. Effects on chemical composition and LDL-oxidizability. | 1999 Nov 1 |
1 |
| 48 |
10563066 | International multicentre comparison of cerivastatin with placebo and simvastatin for the treatment of patients with primary hypercholesterolaemia. International Cerivastatin Study Group. | 1999 Jun |
1 |
| 49 |
10617243 | A double-blind placebo controlled trial of simvastatin for the treatment of dyslipidaemia in renal allograft recipients. | 1999 Dec |
2 |
| 50 |
9576425 | Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S) | 1998 Apr 21 |
1 |