Celecoxib

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







37 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34304363 Physiologically based pharmacokinetic (PBPK) modeling for prediction of celecoxib pharmacokinetics according to CYP2C9 genetic polymorphism. 2021 Jul 7
2 33240461 Single nucleotide polymorphisms on CYP2C9 gene among Filipinos and its association with post-operative pain relief via COX-2 inhibitors. 2020 1
3 31274208 Prolonged Pharmacokinetic Interaction Between Capecitabine and a CYP2C9 Substrate, Celecoxib. 2019 Dec 3
4 29377603 Effects of Ojeok-san on the Pharmacokinetics of Celecoxib at Steady-state in Healthy Volunteers. 2018 Jul 1
5 29563776 Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo. 2018 3
6 30034221 Does celecoxib inhibit agomelatine metabolism via CYP2C9 or CYP1A2? 2018 1
7 30219715 Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C9*3 variants. 2018 Oct 6
8 27864660 Effects of CYP2C9 genetic polymorphisms on the pharmacokinetics of celecoxib and its carboxylic acid metabolite. 2017 Mar 15
9 25585969 Novel Use of Pharmacogenetic Testing in the Identification of CYP2C9 Polymorphisms Related to NSAID-Induced Gastropathy. 2015 May 1
10 26360837 Influence of genetic polymorphisms on the pharmacokinetics of celecoxib and its two main metabolites in healthy Chinese subjects. 2015 Nov 15 5
11 23996211 Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib. 2013 Dec 4
12 28520369 Celecoxib Therapy and CYP2C9 Genotype 2012 4
13 19233181 Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma. 2009 Jun 4
14 19422321 Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine? 2009 Jun 2
15 19515014 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. 2009 1
16 19925388 Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance. 2009 Sep 2
17 20167001 New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I. 2009 Dec 1
18 17999057 Clinical use and pharmacological properties of selective COX-2 inhibitors. 2008 Mar 1
19 17696334 CYP2C9 structure-metabolism relationships: optimizing the metabolic stability of COX-2 inhibitors. 2007 Sep 6 1
20 16513453 Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3. 2006 Mar 1
21 16952496 Is celecoxib an inducer of cytochrome P450 3A4 in subjects carrying the CYP2C9*3 allele? 2006 Sep 1
22 17022718 [Clinical pharmacogenomics for CYP2C8 and CYP2C9: general concepts and application to the use of NSAIDs]. 2006 Jul-Aug 1
23 15569819 Cytochrome P4502C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells. 2005 Feb 2
24 16118328 Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same? 2005 Nov 1
25 16153401 Cytochrome P450 2C9 genotype: impact on celecoxib safety and pharmacokinetics in a pediatric patient. 2005 Sep 1
26 14970301 Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication. 2004 Feb 1
27 15058617 Drug interactions in dentistry: the importance of knowing your CYPs. 2004 Mar 1
28 12603175 Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib. 2003 1
29 12893985 Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. 2003 Aug 8
30 14768975 Influence of rifampicin pretreatment on the pharmacokinetics of celecoxib in healthy male volunteers. 2003 2
31 11816012 Investigation of the pharmacokinetics of celecoxib by liquid chromatography-mass spectrometry. 2002 Feb 1
32 12392591 Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase. 2002 Oct 8
33 11337938 In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics. 2001 Apr 14
34 11601668 Clinical implications of drug interactions with coxibs. 2001 Oct 2
35 10749518 Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor. 2000 Mar 2
36 10773015 Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor. 2000 May 3
37 10463513 Selective cyclooxygenase-2 inhibitors for the treatment of arthritis. 1999 Jul 1