Cyclophosphamide

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







14 Article(s)
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Pub. Year
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1 32390827 Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients. 2020 3
2 28744217 The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation. 2017 1
3 26894931 Cyclophosphamide treatment-induced leukopenia rates in ANCA-associated vasculitis are influenced by variant CYP450 2C9 genotypes. 2016 Mar 2
4 24768782 Significant role of CYP450 genetic variants in cyclophosphamide based breast cancer treatment outcomes: a multi-analytical strategy. 2014 Jul 1 1
5 19501186 In vitro micronucleus test in HepG2 transformants expressing a series of human cytochrome P450 isoforms with chemicals requiring metabolic activation. 2009 Jun-Jul 1
6 18496131 Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. 2008 Jun 1
7 17580253 Fluconazole coadministration concurrent with cyclophosphamide conditioning may reduce regimen-related toxicity postmyeloablative hematopoietic cell transplantation. 2007 Jul 3
8 16183265 Pharmacogenetics of cyclophosphamide in patients with hematological malignancies. 2006 Jan 1
9 16475710 CYP2C9 polymorphisms in human tumors. 2006 Jan-Feb 1
10 12684728 Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes. 2003 Jun 4
11 10991840 Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect. 2000 Oct 6
12 9157990 Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines. 1997 May 15 1
13 9241661 Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation. 1997 Jun 7
14 9331082 Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes. 1997 Oct 1 1