Serine

protein tyrosine kinase 2 beta ; Homo sapiens







81 Article(s)
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51 12196460 Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes. 2002 Sep 1
52 12435806 Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor. 2002 Dec 2
53 11116148 Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta. 2001 Mar 16 1
54 11313365 Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343. 2001 Jul 20 2
55 11319202 Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway. 2001 Apr 24 1
56 11373274 Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase. 2001 Jul 13 6
57 11535620 Protein kinase B phosphorylates AHNAK and regulates its subcellular localization. 2001 Sep 3 1
58 11598301 Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. 2001 Oct 12 1
59 11679435 Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state. 2001 Nov 1
60 11707620 Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. 2001 Nov 13 2
61 11733864 Role of three FKHR phosphorylation sites in insulin inhibition of FKHR action in hepatocytes. 2001 Nov 4
62 10722653 Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. 2000 Mar 24 1
63 10788440 Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. 2000 May 5 3
64 10874027 Dual regulation of platelet protein kinase B. 2000 Sep 8 3
65 10898514 cAMP-mediated growth inhibition of lymphoid cells in G1: rapid down-regulation of cyclin D3 at the level of translation. 2000 Jun 1
66 11035810 Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. 2000 Oct 24 1
67 11043856 Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from Type II diabetic subjects. 2000 Sep 1
68 10187855 Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. 1999 Apr 9 2
69 10208883 Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site. 1999 Apr 21 1
70 10377430 Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. 1999 Jun 22 2
71 10497255 Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. 1999 Oct 1 2
72 10567225 Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. 1999 Dec 1 3
73 10576742 Phosphorylation and regulation of Raf by Akt (protein kinase B). 1999 Nov 26 1
74 10601311 Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252. 1999 Dec 24 2
75 10601992 Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP. 1999 Dec 2
76 10637513 Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism. 1999 Dec 23 5
77 9202156 cAMP stimulates protein kinase B in a Wortmannin-insensitive manner. 1997 Jun 9 1
78 7600304 Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. 1995 Jan 1
79 7637810 Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. 1995 Aug 17 1
80 7518463 Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae. 1994 Jul 1
81 8260646 The interleukin-2 receptor complex and signal transduction: role of the beta-chain. 1993 Oct 1