Ceramides

protein tyrosine kinase 2 beta ; Homo sapiens







17 Article(s)
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1 34962430 Insulin regulates Nedd4-2 via a PKB-dependent mechanism in HEI-OC1 auditory cells-crosstalks with sphingolipid and cAMP signaling. 2022 Jan 1
2 18996148 Regulation of ceramide-induced neuronal death: cell metabolism meets neurodegeneration. 2009 Mar 1
3 19303901 Glycosphingolipids and insulin resistance. 2009 May-Jul 1
4 14970205 Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. 2004 Apr 30 2
5 15220355 Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. 2004 Aug 27 2
6 12525490 A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. 2003 Mar 21 1
7 12569071 Interleukin-1beta inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide. 2003 Feb 3
8 12750385 Oxidized low density lipoprotein inhibits macrophage apoptosis by blocking ceramide generation, thereby maintaining protein kinase B activation and Bcl-XL levels. 2003 Jul 4 1
9 14560023 Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. 2003 Nov 12
10 11706021 Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide. 2002 Jan 25 1
11 11897496 Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A. 2002 Jun 1
12 12213802 Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. 2002 Nov 8 1
13 11171115 Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation. 2001 Mar 1 1
14 11270673 Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. 2001 Feb 3
15 11574400 A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate. 2001 Oct 1
16 10788440 Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. 2000 May 5 4
17 10467260 Overexpression of Akt (protein kinase B) confers protection against apoptosis and prevents formation of ceramide in response to pro-apoptotic stimuli. 1999 Sep 15 1