| 1 |
33832505 | The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells. | 2021 Apr 8 |
2 |
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34543986 | Human urinary kininogenase reduces the endothelial injury by inhibiting Pyk2/MCU pathway. | 2021 Nov |
3 |
| 3 |
34909713 | Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses. | 2021 Jun |
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| 4 |
31634727 | Calcium promotes differentiation in ameloblast-like LS8 cells by downregulation of phosphatidylinositol 3 kinase /protein kinase B pathway. | 2020 Jan |
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| 5 |
32234888 | Potential Anticancer Effect of Calcium-mediated Src Degradation on Hormone-dependent Breast Cancer. | 2020 Apr |
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| 6 |
30478830 | SP1, MYC, CTNNB1, CREB1, JUN genes as potential therapy targets for neuropathic pain of brain. | 2019 May |
1 |
| 7 |
30894012 | Focal Adhesion Kinases in Platelet Function and Thrombosis. | 2019 May |
1 |
| 8 |
28228260 | Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment. | 2017 Feb 21 |
1 |
| 9 |
27169587 | Sound Waves Induce Neural Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells via Ryanodine Receptor-Induced Calcium Release and Pyk2 Activation. | 2016 Oct |
1 |
| 10 |
27616980 | Transient Receptor Potential Vanilloid 4 Inhibits γ-Aminobutyric Acid-Activated Current in Hippocampal Pyramidal Neurons. | 2016 |
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| 11 |
23584706 | Expression of insulin signalling components in the sensory epithelium of the human saccule. | 2013 Jun |
2 |
| 12 |
22581436 | PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells. | 2012 Nov |
1 |
| 13 |
21238585 | CD44-mediated elongated T cell spreading requires Pyk2 activation by Src family kinases, extracellular calcium, phospholipase C and phosphatidylinositol-3 kinase. | 2011 May |
2 |
| 14 |
20348095 | Calcium mobilization triggered by the chemokine CXCL12 regulates migration in wounded intestinal epithelial monolayers. | 2010 May 21 |
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| 15 |
20400701 | Calcium-activated pathways and oxidative burst mediate zymosan-induced signaling and IL-10 production in human macrophages. | 2010 May 15 |
2 |
| 16 |
20688918 | Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. | 2010 Oct 8 |
1 |
| 17 |
20826662 | Proline-rich tyrosine kinase 2 regulates hippocampal long-term depression. | 2010 Sep 8 |
3 |
| 18 |
21429240 | HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase. | 2010 Dec 7 |
2 |
| 19 |
19563802 | Oxytocin stimulates in vitro angiogenesis via a Pyk-2/Src-dependent mechanism. | 2009 Nov 1 |
2 |
| 20 |
18290763 | Calcium-dependent Pyk2 activation: a role for calmodulin? | 2008 Mar 15 |
3 |
| 21 |
17205062 | The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes. | 2007 May |
2 |
| 22 |
17327421 | Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene. | 2007 May |
1 |
| 23 |
17686966 | Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones. | 2007 Nov |
2 |
| 24 |
16574377 | Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: roles of calcium, Src, Rho kinase, and the cytoskeleton. | 2006 Nov |
1 |
| 25 |
16611900 | Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. | 2006 May |
1 |
| 26 |
16870295 | Involvement of endoplasmic reticulum in hepatitis B virus replication. | 2006 Nov |
1 |
| 27 |
15601262 | Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes. | 2005 May 15 |
3 |
| 28 |
15919658 | Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells. | 2005 Aug 5 |
2 |
| 29 |
14676843 | Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2. | 2004 Feb 12 |
2 |
| 30 |
14729602 | Phosphatidylinositol triphosphate kinase-dependent and c-jun NH2-terminal kinase-dependent induction of telomerase by calcium requires Pyk2. | 2004 Jan 1 |
4 |
| 31 |
15226266 | Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation. | 2004 Jul |
1 |
| 32 |
11916084 | Proline-rich tyrosine kinase 2 and focal adhesion kinase are involved in different phases of platelet activation by vWF. | 2002 Mar |
1 |
| 33 |
12074576 | Thrombin-stimulated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases. | 2002 Jun 28 |
2 |
| 34 |
12193071 | Endothelin signalling and regulation of protein kinases in glomerular mesangial cells. | 2002 Aug |
1 |
| 35 |
12231407 | Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts. | 2002 Sep |
1 |
| 36 |
12358757 | Activity-dependent NMDA receptor-mediated activation of protein kinase B/Akt in cortical neuronal cultures. | 2002 Sep |
3 |
| 37 |
11278472 | 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors block calcium-dependent tyrosine kinase Pyk2 activation by angiotensin II in vascular endothelial cells. involvement of geranylgeranylation of small G protein Rap1. | 2001 May 11 |
5 |
| 38 |
11698270 | HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling. | 2001 Nov 15 |
1 |
| 39 |
11743208 | Calcium signaling by HBx protein in hepatitis B virus DNA replication. | 2001 Dec 14 |
2 |
| 40 |
10704819 | RAFTK/Pyk2-mediated cellular signalling. | 2000 Mar |
2 |
| 41 |
10766859 | Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2+) levels. | 2000 Apr 21 |
1 |
| 42 |
10022914 | Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. | 1999 Mar |
3 |
| 43 |
10597281 | RAFTK/PYK2-dependent and -independent apoptosis in multiple myeloma cells. | 1999 Nov 18 |
3 |
| 44 |
9603937 | Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling. | 1998 Jun 5 |
1 |
| 45 |
8999881 | An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells. | 1997 Jan 17 |
7 |
| 46 |
9099753 | Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism. | 1997 Apr 18 |
2 |
| 47 |
9310476 | Characterization of signal transduction pathways in human bone marrow endothelial cells. | 1997 Sep 15 |
1 |
| 48 |
9366396 | Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells. | 1997 Nov 15 |
2 |
| 49 |
8939945 | Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation. | 1996 Nov 22 |
4 |
| 50 |
7544443 | Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. | 1995 Aug 31 |
2 |