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33633735 | Full Activation of Kinase Protein Kinase B by Phosphoinositide-Dependent Protein Kinase-1 and Mammalian Target of Rapamycin Complex 2 Is Required for Early Natural Killer Cell Development and Survival. | 2020 |
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| 2 |
30198788 | Alpha 2-Adrenergic Receptor Agonist Brimonidine Stimulates ERK1/2 and AKT Signaling via Transactivation of EGF Receptors in the Human MIO-M1 Müller Cell Line. | 2019 Jan |
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| 3 |
25713079 | A role for the tyrosine kinase Pyk2 in depolarization-induced contraction of vascular smooth muscle. | 2015 Apr 3 |
2 |
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21195757 | Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells. | 2011 Apr |
2 |
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21592956 | mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. | 2011 Jul 15 |
2 |
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20044479 | Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. | 2010 Feb 26 |
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19115062 | Insulin enhances proliferation and viability of human umbilical vein endothelial cells. | 2009 Feb |
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18160431 | Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance. | 2008 Mar |
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| 9 |
18557931 | Infliximab inhibits DNA repair in ultraviolet B-irradiated premalignant keratinocytes. | 2008 Nov |
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| 10 |
16234845 | Increased phosphorylation of protein kinase B and related substrates after traumatic brain injury in humans and rats. | 2006 Jul |
2 |
| 11 |
14611643 | WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate. | 2004 Feb 15 |
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| 12 |
14668339 | Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells. | 2004 Apr 9 |
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| 13 |
15149865 | Impact of cholesterol depletion on shape changes, actin reorganization, and signal transduction in neutrophil-like HL-60 cells. | 2004 Jun 10 |
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| 14 |
14560023 | Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. | 2003 Nov |
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| 15 |
14637150 | Transforming growth factor-beta1 stimulated protein kinase B serine-473 and focal adhesion kinase tyrosine phosphorylation dependent on cell adhesion in human hepatocellular carcinoma SMMC-7721 cells. | 2003 Dec 12 |
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| 16 |
11884412 | Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load. | 2002 May 17 |
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| 17 |
12000750 | Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. | 2002 Aug 2 |
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| 18 |
12164932 | Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling. | 2002 Jul |
2 |
| 19 |
12167717 | Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. | 2002 Sep |
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| 20 |
12196460 | Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes. | 2002 Sep |
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| 21 |
12435806 | Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor. | 2002 Dec |
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| 22 |
11373274 | Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase. | 2001 Jul 13 |
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| 23 |
11598301 | Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. | 2001 Oct 12 |
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| 24 |
11679435 | Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state. | 2001 Nov |
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| 25 |
11707620 | Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. | 2001 Nov 13 |
2 |
| 26 |
11733864 | Role of three FKHR phosphorylation sites in insulin inhibition of FKHR action in hepatocytes. | 2001 Nov |
4 |
| 27 |
10722653 | Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. | 2000 Mar 24 |
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| 28 |
10788440 | Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. | 2000 May 5 |
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| 29 |
10833263 | Studies on the phosphorylation of protein kinase B by Ca(2+)/calmodulin-dependent protein kinases. | 2000 Jun |
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| 30 |
10874027 | Dual regulation of platelet protein kinase B. | 2000 Sep 8 |
4 |
| 31 |
11043856 | Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from Type II diabetic subjects. | 2000 Sep |
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| 32 |
10377430 | Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. | 1999 Jun 22 |
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| 33 |
10601311 | Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252. | 1999 Dec 24 |
4 |
| 34 |
10601992 | Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP. | 1999 Dec |
2 |
| 35 |
10637513 | Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism. | 1999 Dec 23 |
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| 36 |
9202156 | cAMP stimulates protein kinase B in a Wortmannin-insensitive manner. | 1997 Jun 9 |
1 |
| 37 |
9228007 | Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. | 1997 Jul 25 |
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