Hydrogen Peroxide

protein tyrosine kinase 2 beta ; Homo sapiens







26 Article(s)
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1 34949154 24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation. 2022 Jan 1
2 34026753 Pyk2/MCU Pathway as a New Target for Reversing Atherosclerosis. 2021 1
3 34543986 Human urinary kininogenase reduces the endothelial injury by inhibiting Pyk2/MCU pathway. 2021 Nov 4
4 32792487 Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells. 2020 Aug 14 4
5 30637731 Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation. 2019 Jan 13 1
6 28831286 Standardized Kaempferia parviflora Extract Inhibits Intrinsic Aging Process in Human Dermal Fibroblasts and Hairless Mice by Inhibiting Cellular Senescence and Mitochondrial Dysfunction. 2017 1
7 23241309 PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation. 2013 Apr 2
8 23485815 Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H₂O₂-induced neural progenitor cell injury. 2013 Jun 14 1
9 20688918 Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. 2010 Oct 8 1
10 19545622 CaMKII knockdown attenuates H2O2-induced phosphorylation of ERK1/2, PKB/Akt, and IGF-1R in vascular smooth muscle cells. 2009 Sep 15 1
11 20029537 Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells. 2009 Dec 2
12 18542050 TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. 2008 Jul 2
13 17164397 Effect of hydrogen peroxide on ROMK channels in the cortical collecting duct. 2007 Apr 5
14 17406055 Role of receptor and nonreceptor protein tyrosine kinases in H2O2-induced PKB and ERK1/2 signaling. 2007 7
15 16720330 Hydrogen peroxide acts as relaxing factor in human vascular smooth muscle cells independent of map-kinase and nitric oxide. 2006 Sep 1 2
16 16998541 Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells. 2006 Jul 12
17 16244116 PAF-receptor antagonists, lovastatin, and the PTK inhibitor genistein inhibit H2O2 secretion by macrophages cultured on oxidized-LDL matrices. 2005 Nov 3
18 14729104 Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death. 2004 Jan 12 2
19 15025937 Distinct roles of Ca2+, calmodulin, and protein kinase C in H2O2-induced activation of ERK1/2, p38 MAPK, and protein kinase B signaling in vascular smooth muscle cells. 2004 Apr 4
20 12682076 Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity. 2003 Jun 6 1
21 12213802 Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. 2002 Nov 8 2
22 12361705 Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathways. 2002 Oct 15 7
23 10965882 Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II. 2000 Sep 1
24 10578066 Activation of protein kinase B induced by H(2)O(2) and heat shock through distinct mechanisms dependent and independent of phosphatidylinositol 3-kinase. 1999 Dec 1
25 10593919 Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways. 1999 Dec 17 1
26 8778024 Oxidative stress triggers tyrosine phosphorylation in B cells through a redox- and inflammatory cytokine-sensitive mechanism. 1996 Mar 1