Cyclophosphamide

cytochrome P450 family 2 subfamily C member 19 ; Homo sapiens







23 Article(s)
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Pub. Year
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1 32496149 Drug metabolising enzyme polymorphisms and chemotherapy-related ovarian failure in young breast cancer survivors. 2021 Apr 2
2 34114066 Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients. 2021 Sep 1
3 30500380 Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4. 2019 Jan 15 1
4 28976264 Epistatic interactions among CYP2C19*2, CYP3A4 and GSTP1 on the cyclophosphamide therapy in lupus nephritis patients. 2017 Oct 2
5 26456622 Genetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus. 2016 Feb 1
6 26894931 Cyclophosphamide treatment-induced leukopenia rates in ANCA-associated vasculitis are influenced by variant CYP450 2C9 genotypes. 2016 Mar 1
7 27991432 The effect of proton pump inhibitors on the CYP2C19 enzyme activity evaluated by the pantoprazole-13C breath test in GERD patients: clinical relevance for personalized medicine. 2016 Dec 17 1
8 26159874 CYP2C19 Phenoconversion by Routinely Prescribed Proton Pump Inhibitors Omeprazole and Esomeprazole: Clinical Implications for Personalized Medicine. 2015 Sep 1
9 24768782 Significant role of CYP450 genetic variants in cyclophosphamide based breast cancer treatment outcomes: a multi-analytical strategy. 2014 Jul 1 1
10 21741706 Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients. 2012 Jan 2
11 20358205 Pharmacogenetics of cyclophosphamide and CYP2C19 polymorphism in Thai systemic lupus erythematosus. 2011 Sep 4
12 21543025 Cytochrome P450 polymorphisms and the response of lupus nephritis to cyclophosphamide therapy. 2011 May 1
13 21108329 Allelic variations in CYP2B6 and CYP2C19 and survival of patients receiving cyclophosphamide prior to myeloablative hematopoietic stem cell transplantation. 2010 Dec 1
14 21175440 The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation. 2010 Dec 3
15 18496131 Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. 2008 Jun 1
16 18854824 CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype. 2008 Oct 21 2
17 17407229 Cytochrome P450 polymorphism as a predictor of ovarian toxicity to pulse cyclophosphamide in systemic lupus erythematosus. 2007 Apr 1
18 16183265 Pharmacogenetics of cyclophosphamide in patients with hematological malignancies. 2006 Jan 1
19 16550168 Cytochrome P450 pharmacogenetics and cancer. 2006 Mar 13 1
20 16116487 Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19. 2005 1
21 15248218 Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis. 2004 Jul 1
22 12684728 Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes. 2003 Jun 3
23 9241661 Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation. 1997 Jun 6