Diazepam

cytochrome P450 family 2 subfamily C member 19 ; Homo sapiens







40 Article(s)
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1 35001019 Effects of CYP2C19*17 genetic polymorphisms on plasma and saliva concentrations of diazepam in patients with alcohol withdrawal syndrome. 2022 Apr 1 3
2 34720165 Effects of CYP2C19*17 Genetic Polymorphisms on the Steady-State Concentration of Diazepam in Patients With Alcohol Withdrawal Syndrome. 2021 Oct 3
3 32134726 How do CYP2C19*2 and CYP2C19*17 genetic polymorphisms affect the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome? 2020 Mar 5 6
4 27099220 Role of CYP2C19 gene polymorphism in acute alcohol withdrawal treatment with loading dose of diazepam in a South Indian population. 2016 Jul 2
5 27991432 The effect of proton pump inhibitors on the CYP2C19 enzyme activity evaluated by the pantoprazole-13C breath test in GERD patients: clinical relevance for personalized medicine. 2016 Dec 17 1
6 26020462 Extreme Duration of Diazepam-Associated Sedation in a Patient With Alcohol Delirium and CYP2C19 Polymorphisms. 2015 Aug 1
7 26159874 CYP2C19 Phenoconversion by Routinely Prescribed Proton Pump Inhibitors Omeprazole and Esomeprazole: Clinical Implications for Personalized Medicine. 2015 Sep 1
8 28520370 Diazepam Therapy and CYP2C19 Genotype 2012 1
9 20468063 Association between CYP2C19 polymorphism and depressive symptoms. 2010 Sep 4
10 19571432 Simultaneous expression of plural forms of human cytochrome P450 at desired ratios in HepG2 cells: adenovirus-mediated tool for cytochrome P450 reconstitution. 2009 1
11 18076219 Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects. 2008 1
12 18175099 Midazolam and other benzodiazepines. 2008 1
13 17375979 The role of pharmacogenetics in the metabolism of antiepileptic drugs: pharmacokinetic and therapeutic implications. 2007 1
14 17635335 Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines. 2007 Aug 1
15 29788670 Personalized medicine for eradication of Helicobacter pylori. 2007 Aug 1
16 16307177 Novel mutations in the cytochrome P450 2C19 gene: a pitfall of the PCR-RFLP method for identifying a common mutation. 2006 1
17 16771600 The AmpliChip CYP450 genotyping test: Integrating a new clinical tool. 2006 1
18 16338280 CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia. 2005 Dec 2
19 12708941 Phenytoin-diazepam interaction. 2003 May 1
20 12869636 Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. 2003 Aug 1
21 11927837 Analysis of the CYP2C19 polymorphism in a North-eastern Thai population. 2002 Apr 1
22 12222994 Clinical significance of the cytochrome P450 2C19 genetic polymorphism. 2002 1
23 12464799 Identification and functional characterization of new potentially defective alleles of human CYP2C19. 2002 Dec 1
24 11510629 Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole. 2001 1
25 11560871 Effects of CYP3A4 inhibition by diltiazem on pharmacokinetics and dynamics of diazepam in relation to CYP2C19 genotype status. 2001 Oct 3
26 11694260 CYP2C19 genotype determines enzyme activity and inducibility of S-mephenytoin hydroxylase. 2001 Nov 1
27 10886465 Pharmacogenetics and psychopharmacotherapy. 2000 Jun 1
28 11038161 Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s. 2000 Nov 3
29 10411572 A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin. 1999 Aug 1
30 10613621 Effect of the gene dosage of CgammaP2C19 on diazepam metabolism in Chinese subjects. 1999 Dec 2
31 9923577 Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitro. 1998 Nov-Dec 1
32 9263374 Single-dose pharmacokinetics and pharmacodynamics of oral triazolam in relation to cytochrome P4502C19 (CYP2C19) activity. 1997 Aug 1
33 9435993 Selective serotonin reuptake inhibitors and CNS drug interactions. A critical review of the evidence. 1997 Dec 2
34 8904619 The elimination of diazepam in Chinese subjects is dependent on the mephenytoin oxidation phenotype. 1996 Oct 1
35 8905790 [Pharmacokinetics of zotepine and various factors affecting that of zotepine]. 1996 Apr 1
36 8923565 Possible inhibitory effect of diazepam on the metabolism of zotepine, an antipsychotic drug. 1996 Oct 1
37 8930576 Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs. 1996 Oct 2
38 7628184 Interethnic difference in omeprazole's inhibition of diazepam metabolism. 1995 Jul 1
39 8521680 Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. 1995 Sep 2
40 8806399 Cytochrome P450 isozymes and antiepileptic drug interactions. 1995 1