| 1 |
35405742 | YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site. | 2022 Jun 1 |
1 |
| 2 |
32043360 | Plant extracts rich in polyphenols: antibacterial agents and natural preservatives for meat and meat products. | 2021 |
1 |
| 3 |
34728715 | Nucleolar translocation of human DNA topoisomerase II by ATP depletion and its disruption by the RNA polymerase I inhibitor BMH-21. | 2021 Nov 2 |
1 |
| 4 |
32266332 | Design, synthesis, in silico studies and biological evaluation of 5-((E)-4-((E)-(substituted aryl/alkyl)methyl)benzylidene)thiazolidine-2,4-dione derivatives. | 2020 Dec |
1 |
| 5 |
31512855 | Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ. | 2019 Oct 21 |
1 |
| 6 |
31675229 | Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. | 2019 Nov 27 |
1 |
| 7 |
29710509 | DNA gyrase inhibitors: Progress and synthesis of potent compounds as antibacterial agents. | 2018 Jul |
1 |
| 8 |
30607321 | Taxifolin as dual inhibitor of Mtb DNA gyrase and isoleucyl-tRNA synthetase: in silico molecular docking, dynamics simulation and in vitro assays. | 2018 |
1 |
| 9 |
28075472 | Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways. | 2017 Feb |
3 |
| 10 |
28580714 | Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90. | 2017 Dec |
1 |
| 11 |
27793284 | Single-Molecule Confocal FRET Microscopy to Dissect Conformational Changes in the Catalytic Cycle of DNA Topoisomerases. | 2016 |
1 |
| 12 |
28510216 | DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression. | 2016 Nov |
1 |
| 13 |
28510224 | DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression. | 2016 Sep |
1 |
| 14 |
26174721 | Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors. | 2015 Sep |
1 |
| 15 |
24309019 | A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation. | 2014 Mar 1 |
1 |
| 16 |
24674625 | The mechanism of negative DNA supercoiling: a cascade of DNA-induced conformational changes prepares gyrase for strand passage. | 2014 Apr |
1 |
| 17 |
24974097 | Reprint of "The mechanism of negative DNA supercoiling: a cascade of DNA-induced conformational changes prepares gyrase for strand passage". | 2014 Aug |
1 |
| 18 |
22343632 | Potassium ions are required for nucleotide-induced closure of gyrase N-gate. | 2012 Mar 30 |
1 |
| 19 |
22977179 | The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle. | 2012 Nov |
1 |
| 20 |
21530019 | Combining molecular docking and QSAR studies for modelling the antigyrase activity of cyclothialidine derivatives. | 2011 Jul |
1 |
| 21 |
21817063 | DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passage. | 2011 Aug 23 |
1 |
| 22 |
21904817 | Exploiting bacterial DNA gyrase as a drug target: current state and perspectives. | 2011 Nov |
1 |
| 23 |
17220464 | Molecular cloning of apicoplast-targeted Plasmodium falciparum DNA gyrase genes: unique intrinsic ATPase activity and ATP-independent dimerization of PfGyrB subunit. | 2007 Mar |
1 |
| 24 |
17228868 | Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. | 2007 Jan 25 |
2 |
| 25 |
17691945 | Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents. | 2007 |
1 |
| 26 |
16397501 | Mechanochemical analysis of DNA gyrase using rotor bead tracking. | 2006 Jan 5 |
1 |
| 27 |
16711736 | Exhaustive de novo design of low-molecular-weight fragments against the ATP-binding site of DNA-gyrase. | 2006 May-Jun |
1 |
| 28 |
16246146 | Coupling ATP hydrolysis to DNA strand passage in type IIA DNA topoisomerases. | 2005 Dec |
1 |
| 29 |
15019780 | Nucleotide binding to DNA gyrase causes loss of DNA wrap. | 2004 Mar 26 |
1 |
| 30 |
11237612 | Locking the ATP-operated clamp of DNA gyrase: probing the mechanism of strand passage. | 2001 Mar 9 |
1 |
| 31 |
11278845 | Atp-bound topoisomerase ii as a target for antitumor drugs. | 2001 May 11 |
2 |
| 32 |
11399091 | gyrB-225, a mutation of DNA gyrase that compensates for topoisomerase I deficiency: investigation of its low activity and quinolone hypersensitivity. | 2001 Jun 22 |
1 |
| 33 |
10782694 | Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors. | 2000 Apr 17 |
2 |
| 34 |
10571989 | Locking the DNA gate of DNA gyrase: investigating the effects on DNA cleavage and ATP hydrolysis. | 1999 Oct 26 |
1 |
| 35 |
9657678 | Identification of a residue involved in transition-state stabilization in the ATPase reaction of DNA gyrase. | 1998 Jul 7 |
1 |
| 36 |
9756859 | Hydrolysis of ATP at only one GyrB subunit is sufficient to promote supercoiling by DNA gyrase. | 1998 Oct 9 |
2 |
| 37 |
9016655 | Probing the role of the ATP-operated clamp in the strand-passage reaction of DNA gyrase. | 1996 Dec 15 |
1 |
| 38 |
7853333 | Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. | 1995 Feb 3 |
1 |
| 39 |
8248233 | Identifying the catalytic residue of the ATPase reaction of DNA gyrase. | 1993 Dec 1 |
1 |
| 40 |
8383523 | The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. | 1993 Mar 16 |
1 |
| 41 |
1657531 | DNA gyrase: structure and function. | 1991 |
1 |
| 42 |
1964556 | Control of DNA structure and gene expression. | 1990 |
1 |
| 43 |
2548859 | DNA gyrase can supercoil DNA circles as small as 174 base pairs. | 1989 Jun |
1 |
| 44 |
2549608 | Mode of action of the quinolone antimicrobial agents: review of recent information. | 1989 Jul-Aug |
1 |
| 45 |
3025451 | Co-operativity and enzymatic activity in polymer-activated enzymes. A one-dimensional piggy-back binding model and its application to the DNA-dependent ATPase of DNA gyrase. | 1986 Jul 20 |
1 |