| 1 |
34550633 | KMT2A-MAML2 rearrangement emerged and regressed during neuroblastoma therapy without leukemia after 12.8-year follow-up. | 2022 Jan |
2 |
| 2 |
35565244 | Oral Etoposide and Trastuzumab Use for HER2-Positive Metastatic Breast Cancer: A Retrospective Study from the Institut Curie Hospitals. | 2022 Apr 24 |
2 |
| 3 |
35596703 | Functional characterization and clinical significance of super-enhancers in lung adenocarcinoma. | 2022 May 21 |
1 |
| 4 |
35617303 | Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells. | 2022 |
8 |
| 5 |
33446509 | CRISPR/Cas9 Genome Editing of the Human Topoisomerase IIα Intron 19 5' Splice Site Circumvents Etoposide Resistance in Human Leukemia K562 Cells. | 2021 Mar |
3 |
| 6 |
33747282 | Effect of TOP2A and ERCC1 gene polymorphisms on the efficacy and toxicity of cisplatin and etoposide-based chemotherapy in small cell lung cancer patients. | 2021 |
2 |
| 7 |
33941661 | A Role for VCP/p97 in the Processing of Drug-Stabilized TOP2-DNA Covalent Complexes. | 2021 Jul |
1 |
| 8 |
34031359 | Pericentromeric Satellite III transcripts induce etoposide resistance. | 2021 May 24 |
3 |
| 9 |
31836624 | hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase IIα in Human Leukemia K562 Cells with Acquired Resistance to Etoposide. | 2020 Mar |
1 |
| 10 |
32193368 | Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection. | 2020 Mar 19 |
1 |
| 11 |
32414923 | Topoisomerase IIα is essential for maintenance of mitotic chromosome structure. | 2020 Jun 2 |
1 |
| 12 |
31271486 | Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology. | 2019 Oct |
1 |
| 13 |
29514855 | The Novel C-terminal Truncated 90-kDa Isoform of Topoisomerase IIα (TOP2α/90) Is a Determinant of Etoposide Resistance in K562 Leukemia Cells via Heterodimerization with the TOP2α/170 Isoform. | 2018 May |
5 |
| 14 |
27974636 | Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy. | 2017 Jan |
1 |
| 15 |
27974648 | Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform. | 2017 Jan |
9 |
| 16 |
28110185 | Computational analysis of Amsacrine resistance in human topoisomerase II alpha mutants (R487K and E571K) using homology modeling, docking and all-atom molecular dynamics simulation in explicit solvent. | 2017 Mar |
1 |
| 17 |
28611105 | The DNA-Binding Polyamine Moiety in the Vectorized DNA Topoisomerase II Inhibitor F14512 Alters Reparability of the Consequent Enzyme-Linked DNA Double-Strand Breaks. | 2017 Oct |
2 |
| 18 |
25605014 | Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer. | 2015 Feb 20 |
1 |
| 19 |
26421495 | Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells. | 2015 Nov |
1 |
| 20 |
24327541 | The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1. | 2014 Feb |
1 |
| 21 |
24336569 | Genetic screens in human cells using the CRISPR-Cas9 system. | 2014 Jan 3 |
1 |
| 22 |
23163762 | Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor. | 2013 Feb |
1 |
| 23 |
24103454 | MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma. | 2013 Oct 8 |
2 |
| 24 |
22285073 | Expression analysis of TOP2A, MSH2 and MLH1 genes in MCF7 cells at different levels of etoposide resistance. | 2012 Feb |
4 |
| 25 |
22528119 | The polyphenolic ellagitannin vescalagin acts as a preferential catalytic inhibitor of the α isoform of human DNA topoisomerase II. | 2012 Jul |
3 |
| 26 |
22841979 | The structure of DNA-bound human topoisomerase II alpha: conformational mechanisms for coordinating inter-subunit interactions with DNA cleavage. | 2012 Dec 7 |
1 |
| 27 |
20824055 | Topoisomerase II-mediated DNA damage is differently repaired during the cell cycle by non-homologous end joining and homologous recombination. | 2010 Sep 2 |
1 |
| 28 |
19003983 | TOP2A overexpression in hepatocellular carcinoma correlates with early age onset, shorter patients survival and chemoresistance. | 2009 Feb 1 |
1 |
| 29 |
17089011 | DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes. | 2006 Dec |
1 |