Anthracyclines

DNA topoisomerase II alpha ; Homo sapiens







79 Article(s)
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51 20100636 17q12-21 - the pursuit of targeted therapy in breast cancer. 2010 May 1
52 20130985 Association between HER2, TOP2A, and response to anthracycline-based preoperative chemotherapy in high-risk primary breast cancer. 2010 Apr 2
53 20217261 Topoisomerase 2 alpha and the case for individualized breast cancer therapy. 2010 May 1
54 20464479 CEF is superior to CMF for tumours with TOP2A aberrations: a Subpopulation Treatment Effect Pattern Plot (STEPP) analysis on Danish Breast Cancer Cooperative Group Study 89D. 2010 Aug 1
55 20676126 Targeting anthracyclines in early breast cancer: new candidate predictive biomarkers emerge. 2010 Sep 23 1
56 18815879 Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis. 2009 Sep 1
57 19365520 Triple negative breast cancer--current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment. 2009 Mar 3
58 19401546 Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy. 2009 May 6 3
59 19401550 Alterations in the TOP2A and HER2 genes: association with adjuvant anthracycline sensitivity in human breast cancers. 2009 May 6 1
60 19417146 Topoisomerase II{alpha}-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin. 2009 May 2
61 19620488 Outcome of patients with early-stage breast cancer treated with doxorubicin-based adjuvant chemotherapy as a function of HER2 and TOP2A status. 2009 Aug 20 1
62 19914538 Aiming at the target: improved adjuvant medical therapy. 2009 Oct 1
63 19996222 Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer. 2009 Dec 15 2
64 20069504 Evaluation of the predictive value of topoisomerase II alpha in patients with breast carcinoma. 2009 2
65 18258981 HER-2 and topoisomerase II as predictors of response to chemotherapy. 2008 Feb 10 3
66 18332872 Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. 2008 May 1
67 18413646 Phenotypic and genetic characterization of circulating tumor cells by combining immunomagnetic selection and FICTION techniques. 2008 Jul 1
68 18702822 Topoisomerase II alpha gene copy loss has adverse prognostic significance in ERBB2-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts. 2008 Aug 14 1
69 19158039 New understanding of the role of anthracyclines in early-stage breast cancer: patient selection considerations. 2008 Dec 1
70 17260090 Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer. 2007 Dec 2
71 17453369 Amplification of TOP2A and HER-2 genes in breast cancers occurring in patients harbouring BRCA1 germline mutations. 2007 1
72 17922046 HER-2, TOP2A and chromosome 17 alterations in breast cancer. 2007 1
73 16682728 Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. 2006 Jun 1 2
74 16864174 TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer. 2006 1
75 17100565 Simultaneous amplification of HER-2 (ERBB2) and topoisomerase IIalpha (TOP2A) genes--molecular basis for combination chemotherapy in cancer. 2006 Nov 1
76 15628907 Copy number analysis of c-erb-B2 (HER-2/neu) and topoisomerase IIalpha genes in breast carcinoma by quantitative real-time polymerase chain reaction using hybridization probes and fluorescence in situ hybridization. 2005 Jan 2
77 15891995 The incidence of topoisomerase II-alpha genomic alterations in adenocarcinoma of the breast and their relationship to human epidermal growth factor receptor-2 gene amplification: a fluorescence in situ hybridization study. 2005 Apr 1
78 14978790 Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples. 2004 Apr 2
79 15034864 Gene copy mapping of the ERBB2/TOP2A region in breast cancer. 2004 May 1