Quinolones

DNA topoisomerase II alpha ; Homo sapiens







53 Article(s)
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1 31683749 Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents. 2019 Oct 31 1
2 27132191 Detection of amino acid substitutions in the GyrA protein of fluoroquinolone-resistant typhoidal Salmonella isolates using high-resolution mass spectrometry. 2016 May 1
3 26055367 Effect of Qnr on Plasmid Gyrase Toxins CcdB and ParE. 2015 Aug 1
4 26239981 Protective effect of Qnr on agents other than quinolones that target DNA gyrase. 2015 Nov 1
5 26243148 Frequent topoisomerase IV mutations associated with fluoroquinolone resistance in Ureaplasma species. 2015 Nov 1
6 25343976 Squaring up to DNA: pentapeptide repeat proteins and DNA mimicry. 2014 Dec 2
7 22838215 The tip of the iceberg: quinolone-resistance conferred by mutations in gyrA gene in non-typhoidal Salmonella strains. 2012 Jan-Mar 1
8 23008691 Modified ionic liquid cold-induced aggregation dispersive liquid-liquid microextraction combined with spectrofluorimetry for trace determination of ofloxacin in pharmaceutical and biological samples. 2011 1
9 17008172 The worldwide emergence of plasmid-mediated quinolone resistance. 2006 Oct 1
10 17310788 [Ciprofloxacin and antibacterial therapy of respiratory tract infections]. 2006 1
11 12558069 Fluoroquinolones: structure and target sites. 2003 Feb 1
12 12624075 Identification of mycobacterial species by PCR sequencing of quinolone resistance-determining regions of DNA gyrase genes. 2003 Mar 2
13 14502475 On the physical interpretation of QSAR models. 2003 Sep-Oct 2
14 12019094 Quinolone-binding pocket of DNA gyrase: role of GyrB. 2002 Jun 2
15 12582434 [Mechanisms of bacterial resistance to quinolones]. 2002 Mar 1
16 11089230 Quinolone interactions with DNA and DNA gyrase. 2001 1
17 11178337 Advances in DNA gyrase inhibitors. 2001 Feb 1
18 11399091 gyrB-225, a mutation of DNA gyrase that compensates for topoisomerase I deficiency: investigation of its low activity and quinolone hypersensitivity. 2001 Jun 22 1
19 11408214 Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87). 2001 Jul 2
20 11427730 In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites. 2001 Jul 3 1
21 12540265 Targeting DNA gyrase. 2001 Aug 1
22 11053451 DNA gyrase-mediated wrapping of the DNA strand is required for the replication fork arrest by the DNA gyrase-quinolone-DNA ternary complex. 2000 Nov 3 2
23 11097055 The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action. 2000 Aug 1
24 11097062 6-hydroxy derivative as new desfluoroquinolone (DFQ): synthesis and DNA-binding study. 2000 Aug 1
25 11249592 Olamufloxacin. Hokuriku Seiyaku. 2000 Sep 1
26 10377219 Design and synthesis of modified quinolones as antitumoral acridones. 1999 Jun 17 1
27 9703246 Quinolone-resistant mutations of DNA gyrase increase sensitivity to acriflavine. 1998 Jul 1
28 9712890 The DNA gyrase-quinolone complex. ATP hydrolysis and the mechanism of DNA cleavage. 1998 Aug 28 3
29 9717215 Bacterial death by DNA gyrase poisoning. 1998 Jul 1
30 9748648 Bacteriophage T4, a model system for understanding the mechanism of type II topoisomerase inhibitors. 1998 Oct 1 1
31 9207016 DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs. 1997 Jul 15 1
32 9379449 DNA gyrase inhibitory and antimicrobial activities of some diphenic acid monohydroxamides. 1997 Sep 26 1
33 8843280 Mechanism of differential activities of ofloxacin enantiomers. 1996 Aug 2
34 7695300 Effect of pyrimido[1,6-a]benzimidazoles, quinolones, and Ca2+ on the DNA gyrase-mediated cleavage reaction. 1995 Jan 5
35 7853333 Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex. 1995 Feb 3 1
36 7826863 Molecular mechanisms of DNA gyrase inhibition by quinolone antibacterials. 1994 1
37 7868402 Interaction of divalent cations, quinolones and bacteria. 1994 Oct 1
38 7875053 Synthesis and antitumour activities of tetracyclic quinolone antineoplastic agents. 1994 1
39 8137121 On the mechanism of action of quinolone drugs. 1993 Sep 1
40 1319080 Mode of action of new quinolones: the inhibitory activity on DNA gyrase. 1992 1
41 1338309 Synthesis and antitumour activities of quinolone antineoplastic agents. 1992 1
42 1850968 Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases. 1991 Feb 1
43 2162298 Resistance to quinolones in gram-negative microorganisms: mechanisms and prevention. 1990 1
44 2536729 Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes. 1989 Feb 15 1
45 2546584 Mechanism of inhibition of DNA gyrase by quinolone antibacterials: specificity and cooperativity of drug binding to DNA. 1989 May 2 2
46 2546585 Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug--DNA binding model. 1989 May 2 2
47 2549608 Mode of action of the quinolone antimicrobial agents: review of recent information. 1989 Jul-Aug 7
48 2831608 Mode of action of the quinolone antimicrobial agents. 1988 Jan-Feb 1
49 3279489 Specific toxicologic aspects of the quinolones. 1988 Jan-Feb 1
50 3293157 Ciprofloxacin: in vitro activity, mechanism of action, and resistance. 1988 May-Jun 1