Doxorubicin

DNA topoisomerase II alpha ; Homo sapiens







21 Article(s)
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1 35596703 Functional characterization and clinical significance of super-enhancers in lung adenocarcinoma. 2022 May 21 1
2 33904373 Predicting candidate therapeutic drugs for sepsis-induced acute respiratory distress syndrome based on transcriptome profiling. 2021 Dec 2
3 34638362 Expression Patterns of TOP2A and SIRT1 Are Predictive of Survival in Patients with High-Risk Soft Tissue Sarcomas Treated with a Neoadjuvant Anthracycline-Based Chemotherapy. 2021 Sep 29 1
4 32599901 Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma. 2020 Jun 24 1
5 30760286 TOP2A as marker of response to pegylated lyposomal doxorubicin (PLD) in epithelial ovarian cancers. 2019 Feb 13 1
6 31216997 Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms. 2019 Jun 19 1
7 29728799 Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy. 2018 Jul 5
8 28813519 Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors. 2017 2
9 27557643 Treatment of acquired drug resistance in multiple myeloma by combination therapy with XPO1 and topoisomerase II inhibitors. 2016 Aug 24 1
10 26100858 TOP2A gene copy gain predicts response of epithelial ovarian cancers to pegylated liposomal doxorubicin: TOP2A as marker of response to PLD in ovarian cancer. 2015 Sep 1
11 24492650 Loss of protein kinase Cδ/HuR interaction is necessary to doxorubicin resistance in breast cancer cell lines. 2014 Apr 4
12 25406834 Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both topoisomerase II isoforms. 2014 Nov 18 1
13 21768308 Translational control of TOP2A influences doxorubicin efficacy. 2011 Sep 2
14 21188112 Positive response to neoadjuvant cyclophosphamide and doxorubicin in topoisomerase II nonamplified/HER2/neu negative/polysomy 17 absent breast cancer patients. 2010 Aug 20 1
15 19417146 Topoisomerase II{alpha}-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin. 2009 May 6
16 19620488 Outcome of patients with early-stage breast cancer treated with doxorubicin-based adjuvant chemotherapy as a function of HER2 and TOP2A status. 2009 Aug 20 2
17 18574145 Topoisomerase levels determine chemotherapy response in vitro and in vivo. 2008 Jul 1 4
18 16502015 Topoisomerase II-alpha gene deletion is not frequent as its amplification in breast cancer. 2006 Aug 4
19 16935488 Predictive value of HER-2 and Topoisomerase IIalpha in response to primary doxorubicin in breast cancer. 2006 Nov 1
20 17089011 DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes. 2006 Dec 1
21 15765123 Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells. 2005 May 1