p-Aminohippuric Acid

solute carrier family 22 member 6 ; Homo sapiens







54 Article(s)
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1 35508593 Determining the Effects of Chronic Kidney Disease on Organic Anion Transporter1/3 Activity Through Physiologically Based Pharmacokinetic Modeling. 2022 May 5 1
2 32234809 Proteasome Inhibitors Bortezomib and Carfilzomib Stimulate the Transport Activity of Human Organic Anion Transporter 1. 2020 Jun 3
3 32344570 Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions. 2020 Apr 24 4
4 32373203 Organic anion transporters also mediate the drug-drug interaction between imipenem and cilastatin. 2020 Mar 1
5 32981893 Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes. 2020 Dec 1
6 29244191 The role of OAT2 (SLC22A7) in the cyclic nucleotide biokinetics of human erythrocytes. 2018 Aug 2
7 27614971 Roles of organic anion transporters (OATs) in renal proximal tubules and their localization. 2017 Mar 4
8 25477469 Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake. 2015 Feb 15 4
9 26640952 The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3. 2015 2
10 24185403 Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate, a uremic toxin. 2014 Oct 1
11 24747579 Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans. 2014 Aug 1 1
12 25002746 Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport. 2014 Sep 2
13 25239859 Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. 2014 Dec 1
14 23255614 Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives. 2013 Feb 15 2
15 23313623 OAT1 and OAT3: targets of drug-drug interaction between entecavir and JBP485. 2013 Mar 12 1
16 22108572 Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3. 2012 Feb 1
17 22169006 Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule. 2012 Mar 1 1
18 22273603 Organic anion transporters involved in the excretion of bestatin in the kidney. 2012 Feb 1
19 22728397 Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3. 2012 Sep 29 4
20 22875277 α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4). 2012 Oct 1
21 22988478 Evaluation of chinese-herbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1. 2012 2
22 21244849 Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6). 2011 Apr 1 1
23 21561794 Interactions of human organic anion transporter 1 (hOAT1) with substances associated with forensic toxicology. 2011 Jul 2
24 21697612 Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction. 2011 2
25 20460822 Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate. 2010 1
26 20877132 Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. 2010 1
27 19394312 Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural. 2009 Aug 15 1
28 19439489 Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites. 2009 Aug 1
29 19643159 Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. 2009 Oct 1 1
30 18930752 Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling. 2008 Dec 15 3
31 17255469 Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices. 2007 Apr 1
32 17312013 Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts. 2007 Jun 1
33 17353191 The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid. 2007 May 4 1
34 17498396 Difference between pharmacokinetics of mycophenolic acid (MPA) in rats and that in humans is caused by different affinities of MRP2 to a glucuronized form. 2007 1
35 17639024 Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons. 2007 Oct 1
36 17920288 Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3). 2007 Dec 2
37 16597690 Uptake of chemically reactive, DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters. 2006 May 1
38 16724555 Interaction of zalcitabine with human organic anion transporter 1. 2006 May 1
39 16997449 Membrane transport function in primary cultures of human proximal tubular cells. 2006 Dec 7 2
40 15644426 Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8). 2005 May 2
41 15870380 The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. 2005 Aug 1
42 15914676 Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). 2005 Aug 6
43 16038872 Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites. 2005 Aug 15 1
44 15039295 Expression studies and functional characterization of renal human organic anion transporter 1 isoforms. 2004 Apr 10
45 12538807 Interaction of cysteine conjugates with human and rabbit organic anion transporter 1. 2003 Feb 9
46 12605306 Transport of organic anions across the basolateral membrane of proximal tubule cells. 2003 1
47 12606766 Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells. 2003 Mar 1
48 12874449 Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. 2003 Aug 4
49 11744606 The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies. 2002 Jan 3
50 11327718 Isolation of a family of organic anion transporters from human liver and kidney. 2001 May 4 1